[go: up one dir, main page]

ES2130969A1 - Biomembranes for the extemporaneous encapsulation of tetracaine. - Google Patents

Biomembranes for the extemporaneous encapsulation of tetracaine.

Info

Publication number
ES2130969A1
ES2130969A1 ES09602755A ES9602755A ES2130969A1 ES 2130969 A1 ES2130969 A1 ES 2130969A1 ES 09602755 A ES09602755 A ES 09602755A ES 9602755 A ES9602755 A ES 9602755A ES 2130969 A1 ES2130969 A1 ES 2130969A1
Authority
ES
Spain
Prior art keywords
tetracaine
encapsulation
biomembranes
extemporaneous
vesicles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09602755A
Other languages
Spanish (es)
Other versions
ES2130969B1 (en
Inventor
Licas Francisco Molina
Buso Ofelia Vila
Alejano Juan Figueruelo
Florence Bele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitat de Valencia
Original Assignee
Universitat de Valencia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitat de Valencia filed Critical Universitat de Valencia
Priority to ES9602755A priority Critical patent/ES2130969B1/en
Publication of ES2130969A1 publication Critical patent/ES2130969A1/en
Application granted granted Critical
Publication of ES2130969B1 publication Critical patent/ES2130969B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Cosmetics (AREA)

Abstract

Biomembranes for the extemporaneous encapsulation of tetracaine. The procedure for the extemporaneous encapsulation of tetracaine in biomembranes is based on the preparation of large multilamellar liposomes with the incorporation of vitamin F or natural oils in the membranes. The vesicles are then ruptured in an aqueous solution of tetracaine salt, using the osmotic properties of the vesicles, the restructuring of which allows the encapsulation of the tetracaine. Said procedure is characterized by allowing the encapsulation of tetracaine and of other water-soluble active principles in an extemporaneous form, starting from the biomembranes and a solution of a tetracaine salt, or other water-soluble active principles. The practical application of the present invention consists in the topical use of the preparation in lotions, gels or creams for obtaining a local effect of greater efficacy and lower toxicity than conventional preparations.
ES9602755A 1997-02-24 1997-02-24 BIOMEMBRANES FOR EXTEMPORANEOUS ENCAPSULATION OF TETRACAINE. Expired - Fee Related ES2130969B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9602755A ES2130969B1 (en) 1997-02-24 1997-02-24 BIOMEMBRANES FOR EXTEMPORANEOUS ENCAPSULATION OF TETRACAINE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9602755A ES2130969B1 (en) 1997-02-24 1997-02-24 BIOMEMBRANES FOR EXTEMPORANEOUS ENCAPSULATION OF TETRACAINE.

Publications (2)

Publication Number Publication Date
ES2130969A1 true ES2130969A1 (en) 1999-07-01
ES2130969B1 ES2130969B1 (en) 2000-02-16

Family

ID=8297173

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9602755A Expired - Fee Related ES2130969B1 (en) 1997-02-24 1997-02-24 BIOMEMBRANES FOR EXTEMPORANEOUS ENCAPSULATION OF TETRACAINE.

Country Status (1)

Country Link
ES (1) ES2130969B1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244118A1 (en) * 1986-04-29 1987-11-04 Pharmetrix Corporation Controlled release drug delivery system for the peridontal pocket
WO1994005265A1 (en) * 1992-09-10 1994-03-17 Children's Medical Center Corporation Biodegradable polymer matrices for sustained delivery of local anesthetic agents
WO1996034599A1 (en) * 1995-05-01 1996-11-07 Children's Medical Center Corporation Prolonged nerve blockage by the combination of local anesthetics and glucocorticoids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244118A1 (en) * 1986-04-29 1987-11-04 Pharmetrix Corporation Controlled release drug delivery system for the peridontal pocket
WO1994005265A1 (en) * 1992-09-10 1994-03-17 Children's Medical Center Corporation Biodegradable polymer matrices for sustained delivery of local anesthetic agents
WO1996034599A1 (en) * 1995-05-01 1996-11-07 Children's Medical Center Corporation Prolonged nerve blockage by the combination of local anesthetics and glucocorticoids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ADRIENN GESZTES et al. Topical Anesthesia of the Skin by Liposome-Encapsulated tetracaine. ANASTH ANALG 1988; 67: paginas 1079-1081 *

Also Published As

Publication number Publication date
ES2130969B1 (en) 2000-02-16

Similar Documents

Publication Publication Date Title
DE69923181D1 (en) TEMPERATURE SENSITIVE LIPOSOMAL FORMULATION
FI940993A0 (en) Cosmetic salicylic acid delivery system and method for its preparation
AU4711296A (en) Method for loading lipid vesicles
CA2256960A1 (en) High glycerin containing anti-microbial cleansers
BR0314354A (en) Formation for lipophilic people
DK0734252T3 (en) Vincaalkaloid vesicles with increased efficiency and tumor targeting properties
BR9915008A (en) Shampoo composition, and process for preparing it
WO2003032941A3 (en) Cosmetic and/or dermatological active ingredient combination
DK0949909T3 (en) Single-dose, foil-shaped administration form, which disintegrates rapidly upon contact with liquid and contains active substance and especially flavoring
ITMI20020189A1 (en) COMPOSITION FOR PHARMACEUTICAL OR DIETARY USE TO COUNTER HAIR LOSS
ATE260643T1 (en) SYSTEM FOR ADMINISTRATION OF MACROMOLECULAR ACTIVE AGENTS BASED ON MEMBRANE MIMETIC AMPHIPHILS IN AEROSOL FORM
SE9800729L (en) New topical formulation I
NO953580D0 (en) Topical preparation for inhibiting hair growth
EP1216695B8 (en) O/W Emulsions comprising a copolymer of ammonium acryloyl dimethyl taurate and vinylpyrrolidone
WO2002060394A3 (en) Revitalising active complex for the skin
DK1135193T3 (en) Liposome-based tumor therapy agent containing tamoxifen
ES2130969A1 (en) Biomembranes for the extemporaneous encapsulation of tetracaine.
YU49313B (en) A LIPOSOMIC PREPARATION CONTAINING SELEGILIN AND / OR ITS
WO2003011241A8 (en) Utilization of creatinine and/or creatinine derivatives in cosmetic and dermatological preparations
EA199900750A1 (en) AQUEOUS PHARMACEUTICAL COMPOSITION, INCLUDING THE ACTIVE INGREDIENT, IN THE HIGHEST DEGREE IN THE WATER
SE9800730L (en) New topical formulation II
TR200102778T2 (en) Liposome preparations
DE3878696D1 (en) LIPOSOME, THEIR PRODUCTION AND USE AS A VECTOR OF MEDICINAL PRODUCTS.
EP0717980A3 (en) Use of guanidine-imidazole derivatives to assist hair growth stimulation
DE60123419D1 (en) LIQUID MEDICINAL PREPARATIONS FOR THE ORAL ADMINISTRATION OF PROMOTIONAL, BID TREATING MEDICINAL PRODUCTS

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19990701

Kind code of ref document: A1

Effective date: 19990701

FD2A Announcement of lapse in spain

Effective date: 20170531