ES2119588A1 - Novel application of polymeric membranes in the dispensing of pharmaceutical solutions containing quaternary ammonium compounds as preservatives, and corresponding metering container - Google Patents
Novel application of polymeric membranes in the dispensing of pharmaceutical solutions containing quaternary ammonium compounds as preservatives, and corresponding metering containerInfo
- Publication number
- ES2119588A1 ES2119588A1 ES09401260A ES9401260A ES2119588A1 ES 2119588 A1 ES2119588 A1 ES 2119588A1 ES 09401260 A ES09401260 A ES 09401260A ES 9401260 A ES9401260 A ES 9401260A ES 2119588 A1 ES2119588 A1 ES 2119588A1
- Authority
- ES
- Spain
- Prior art keywords
- preservatives
- dispensing
- metering container
- quaternary ammonium
- ammonium compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012528 membrane Substances 0.000 title abstract 4
- 239000003755 preservative agent Substances 0.000 title abstract 2
- 239000003186 pharmaceutical solution Substances 0.000 title 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 title 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 238000011458 pharmacological treatment Methods 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
Landscapes
- Closures For Containers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Said application is characterized in that arranged suitably in the dropper of the metering container, the aforesaid membranes are used to achieve the selective passage of essentially all the active product and the selective retention of essentially all the preservative during the pharmacological treatment. The membrane 5 is coupled between the sets of cylinders 6 and 7 of the parts 3 and 4 of the dropper, remaining in a movable position (Figure 3) by virtue of the existence of a certain clearance between said sets of cylinders or, alternatively, in the fixed position (Figure 4), owing to the lack of said clearance or alternatively, in a fixed position, but with the membrane suitably treated so that it has a small zone or patch which allows the passage of air 8 represents the conduit for exit to the outside.
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19940201823 EP0631770B1 (en) | 1993-06-25 | 1994-06-23 | New use of polymeric membranes in the dispensing of pharmaceutical solutions that contain quaternary ammonium compounds as preservatives and corresponding dose dispensor |
| AT94201823T ATE168553T1 (en) | 1993-06-25 | 1994-06-23 | NEW USE OF POLYMERIC MEMBRANES FOR DISPENSING PHARMACEUTICAL SOLUTIONS CONTAINING QUARTERNARY AMMONIUM PRESERVATIVE COMPOUNDS AND CORRESPONDING DOSAGE CONTAINER |
| FI943066A FI108514B (en) | 1993-06-25 | 1994-06-23 | Use of polymer membranes in the distribution of pharmaceutical solutions containing quaternary ammonium compounds as preservatives |
| DE69411816T DE69411816T2 (en) | 1993-06-25 | 1994-06-23 | New use of polymeric membranes for dispensing pharmaceutical solutions containing quaternary ammonium compounds used as preservatives and corresponding dosing containers |
| CA 2126703 CA2126703C (en) | 1993-06-25 | 1994-06-24 | Use of polymeric membranes in the dispensing of pharmaceutical solutions that contain quaternary ammonium compounds as preservatives and corresponding dose dispenser |
| CN94108914A CN1105230A (en) | 1993-06-25 | 1994-06-24 | Novel use of polymer films for dispensing of liquid medicines containing quaternary ammonium compounds used as preservatives and corresponding dosage dispensers |
| US08/265,409 US5588559A (en) | 1993-06-25 | 1994-06-24 | Use of polymeric membranes in the dispensing of pharmaceutical solutions that contain quaternary ammonium compounds as preservatives and corresponding dose dispenser |
| JP14473294A JP2736227B2 (en) | 1993-06-25 | 1994-06-27 | Dispenser for administration of medicinal solutions containing preservatives |
| AU66007/94A AU671743B2 (en) | 1993-06-25 | 1994-06-27 | New use of polymeric membranes in the dispensing of pharmaceutical solutions that contain quaternary ammonium compounds as preservatives and corresponding dose dispensor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9301443A ES2064286B1 (en) | 1993-06-25 | 1993-06-25 | NEW APPLICATION OF POLYMERIC MEMBRANES IN THE DISPENSATION OF PHARMACEUTICAL SOLUTIONS CONTAINING QUATERNARY AMMONIUM COMPOUNDS AS CONSERVATIVES AND THE CORRESPONDING DISPENSER CONTAINER. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2119588A1 true ES2119588A1 (en) | 1998-10-01 |
| ES2119588B1 ES2119588B1 (en) | 1999-09-16 |
Family
ID=8282359
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9301443A Expired - Fee Related ES2064286B1 (en) | 1993-06-25 | 1993-06-25 | NEW APPLICATION OF POLYMERIC MEMBRANES IN THE DISPENSATION OF PHARMACEUTICAL SOLUTIONS CONTAINING QUATERNARY AMMONIUM COMPOUNDS AS CONSERVATIVES AND THE CORRESPONDING DISPENSER CONTAINER. |
| ES9401260A Expired - Fee Related ES2119588B1 (en) | 1993-06-25 | 1994-06-09 | IMPROVEMENTS INTRODUCED IN THE INVENTION PATENT N-P 9301443/0, BY: NEW APPLICATION OF POLYMERIC MEMBRANES IN THE DISPENSATION OF PHARMACEUTICAL SOLUTIONS CONTAINING QUATERNARY AMMONIUM COMPOUNDS AS CONSERVATIVES, AND CORRESPONDING DOSAGE CONTAINER. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9301443A Expired - Fee Related ES2064286B1 (en) | 1993-06-25 | 1993-06-25 | NEW APPLICATION OF POLYMERIC MEMBRANES IN THE DISPENSATION OF PHARMACEUTICAL SOLUTIONS CONTAINING QUATERNARY AMMONIUM COMPOUNDS AS CONSERVATIVES AND THE CORRESPONDING DISPENSER CONTAINER. |
Country Status (2)
| Country | Link |
|---|---|
| ES (2) | ES2064286B1 (en) |
| RU (1) | RU94022242A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3045906A1 (en) * | 2016-12-02 | 2018-06-07 | University Of Florida Research Foundation, Inc. | Preservative removal from eye drops |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4463880A (en) * | 1982-04-30 | 1984-08-07 | The Regents Of The University Of California | Medicine drop dispenser with anti-bacterial filter |
| US5074440A (en) * | 1990-07-16 | 1991-12-24 | Alcon Laboratories, Inc. | Container for dispensing preservative-free preparations |
| WO1993010015A1 (en) * | 1991-11-15 | 1993-05-27 | Bystrom Steven R | Preservative free sterile fluid dispensing system |
-
1993
- 1993-06-25 ES ES9301443A patent/ES2064286B1/en not_active Expired - Fee Related
-
1994
- 1994-06-09 ES ES9401260A patent/ES2119588B1/en not_active Expired - Fee Related
- 1994-06-25 RU RU94022242/14A patent/RU94022242A/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4463880A (en) * | 1982-04-30 | 1984-08-07 | The Regents Of The University Of California | Medicine drop dispenser with anti-bacterial filter |
| US5074440A (en) * | 1990-07-16 | 1991-12-24 | Alcon Laboratories, Inc. | Container for dispensing preservative-free preparations |
| WO1993010015A1 (en) * | 1991-11-15 | 1993-05-27 | Bystrom Steven R | Preservative free sterile fluid dispensing system |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2064286A1 (en) | 1995-01-16 |
| ES2119588B1 (en) | 1999-09-16 |
| ES2064286B1 (en) | 1995-09-01 |
| RU94022242A (en) | 1996-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19981001 Kind code of ref document: A1 Effective date: 19981001 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20190611 |