ES2112774A1 - Nuevos derivados azolicos con actividad antifungica. - Google Patents
Nuevos derivados azolicos con actividad antifungica.Info
- Publication number
- ES2112774A1 ES2112774A1 ES09502042A ES9502042A ES2112774A1 ES 2112774 A1 ES2112774 A1 ES 2112774A1 ES 09502042 A ES09502042 A ES 09502042A ES 9502042 A ES9502042 A ES 9502042A ES 2112774 A1 ES2112774 A1 ES 2112774A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- atoms
- antifungal activity
- azole derivatives
- new azole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000843 anti-fungal effect Effects 0.000 title abstract 2
- 150000007980 azole derivatives Chemical class 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 125000004429 atom Chemical group 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- -1 polymethylene Polymers 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
COMPUESTOS DE FORMULA I, UTILES COMO ANTIFUNGICOS, EN DONDE AR ES UN GRUPO FENILO OPCIONALMENTE SUSTITUIDO POR UNO O MAS GRUPOS HALOGENO Y/O TRIFLUOROMETILO; R1 ES C1--C4 ALQUILO; R2 ES HIDROGENO O C1-C4 ALQUILO; O BIEN R1 JUNTO CON R2 FORMAN UNA CADENA C2-C4 POLIMETILENO; R3 ES HIDROGENO C1-C4 ALQUILO, C3-C6 CICLOALQUILO, C3-C6 CICLOALQUIL C1-C4 ALQUILO, C1-C4HALOALQUILO O FENIL C1-C4 ALQUILO; A REPRESENTA UN GRUPO HETEROCICLICO DE UNO O DOS ANILLOS CADA UNO DE ELLOS DE 5 A 6 ATOMOS DONDE DE 1 A 4 DE DICHOS ATOMOS SON NITROGENO Y/O OXIGENO Y(O AZUFRE Y QUE PUEDE ESTAR OPCIONALMENTE SUSTITUIDO; Y B REPRESENTA UN GRUPO FENILO O UN GRUPO HETEROCICLICO DE UNO O DOS ANILLOS CADA UNO DE ELLOS DE 5 A 6 ATOMOS DONDE DE 1 A 4 DE DICHOS ATOMOS SON NITROGENO Y/O OXIGENO Y/O AZUFRE, PUDIENDO ESTAR AMBOS GRUPOS OPCIONALMENTE SUSTITUIDOS.
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9502042A ES2112774B1 (es) | 1995-10-20 | 1995-10-20 | Nuevos derivados azolicos con actividad antifungica. |
| JP9507253A JPH10507205A (ja) | 1995-08-02 | 1996-08-02 | 抗真菌活性を有する新規カルボンアミド |
| US08/809,815 US5888941A (en) | 1995-08-02 | 1996-08-02 | Carbozamides with antifungal activity |
| BR9606546A BR9606546A (pt) | 1995-08-02 | 1996-08-02 | Novas carboxamidas com atividade fungicida |
| KR1019970701516A KR970705560A (ko) | 1995-08-02 | 1996-08-02 | 항진균 활성을 갖는 신규한 카르복사미드(new carboxamides with antifungal activity) |
| PCT/EP1996/003419 WO1997005131A1 (en) | 1995-08-02 | 1996-08-02 | New carboxamides with antifungal activity |
| CA002201478A CA2201478A1 (en) | 1995-08-02 | 1996-08-02 | New carboxamides with antifungal activity |
| AU67889/96A AU6788996A (en) | 1995-08-02 | 1996-08-02 | New carboxamides with antifungal activity |
| MX9702380A MX9702380A (es) | 1995-08-02 | 1996-08-02 | Nuevas carboxamidas con actividad antifungica. |
| EP96928404A EP0783502A1 (en) | 1995-08-02 | 1996-08-02 | New carboxamides with antifungal activity |
| ARP960103877A AR004180A1 (es) | 1995-08-02 | 1996-08-05 | Nuevos derivados de pirimidona con actividad antifungica y procedimiento para preparar los mismos. |
| NO971471A NO971471L (no) | 1995-08-02 | 1997-04-01 | Nye karboksamider med fungicid aktivitet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9502042A ES2112774B1 (es) | 1995-10-20 | 1995-10-20 | Nuevos derivados azolicos con actividad antifungica. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2112774A1 true ES2112774A1 (es) | 1998-04-01 |
| ES2112774B1 ES2112774B1 (es) | 1999-05-16 |
Family
ID=8291912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9502042A Expired - Lifetime ES2112774B1 (es) | 1995-08-02 | 1995-10-20 | Nuevos derivados azolicos con actividad antifungica. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2112774B1 (es) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0097469A2 (en) * | 1982-06-18 | 1984-01-04 | Pfizer Limited | Triazole antifungal agents |
| EP0332387A1 (en) * | 1988-03-04 | 1989-09-13 | Sankyo Company Limited | Triazole derivatives, their preparation and their use as fungicides |
| ES2062941A1 (es) * | 1993-03-15 | 1994-12-16 | Uriach & Cia Sa J | Nuevos derivados de azol activos por via oral. |
-
1995
- 1995-10-20 ES ES9502042A patent/ES2112774B1/es not_active Expired - Lifetime
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0097469A2 (en) * | 1982-06-18 | 1984-01-04 | Pfizer Limited | Triazole antifungal agents |
| EP0332387A1 (en) * | 1988-03-04 | 1989-09-13 | Sankyo Company Limited | Triazole derivatives, their preparation and their use as fungicides |
| ES2062941A1 (es) * | 1993-03-15 | 1994-12-16 | Uriach & Cia Sa J | Nuevos derivados de azol activos por via oral. |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2112774B1 (es) | 1999-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
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