ES2165910T3 - Administracion nasal y ocular de cetamina para el tratamiento del dolor y para la desintoxicacion. - Google Patents
Administracion nasal y ocular de cetamina para el tratamiento del dolor y para la desintoxicacion.Info
- Publication number
- ES2165910T3 ES2165910T3 ES95913499T ES95913499T ES2165910T3 ES 2165910 T3 ES2165910 T3 ES 2165910T3 ES 95913499 T ES95913499 T ES 95913499T ES 95913499 T ES95913499 T ES 95913499T ES 2165910 T3 ES2165910 T3 ES 2165910T3
- Authority
- ES
- Spain
- Prior art keywords
- pain
- nasal
- cetamine
- detoxification
- ocular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000001784 detoxification Methods 0.000 title 1
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 abstract 1
- 229960003299 ketamine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
ESTA INVENCION SE HALLA REFERIDA AL TRATAMIENTO DEL DOLOR CRONICO SIN NECESIDAD DE USAR NARCOTICOS Y AL AUTOTRATAMIENTO DE LOS PACIENTES AMBULATORIOS, TENIENDO INTERES TAMBIEN PARA FACILITAR LA DESINTOXICACION Y TRATAMIENTO DE LA ADICION A CIERTAS SUBSTANCIAS. POR TANTO SE TRATA DE UNA INVENCION DIRIGIDA EN LINEAS GENERALES A TRATAR EL DOLOR MEDIANTE LA ADMINISTRACION VIA NASAL DE UNA DOSIS DE KETAMINA PARA ALIVIAR EL DOLOR EN UN SUJETO QUE LO PADEZCA. ASIMISMO TIENE UTILIDAD PARA FACILITAR LA DESINTOXICACION Y TRATAMIENTO DE LOS SUJETOS ADICTOS A CIERTAS SUBSTANCIAS MEDIANTE LA ADMINISTRACION A ESTOS PACIENTES DE UNA DOSIS DE KETAMINA VIA NASAL UTIL PARA LA DESINTOXICACION Y EL TRATAMIENTO DE ADICIONES. EN UNA VERSION ULTERIOR SE FACILITA LA ADMINISTRACION PULMONAR DE KETAMINA MEDIANTE INHALACION. LA ADMINISTRACION VIA NASAL PRESENTA LA VENTAJA DE QUE EL PACIENTE PUEDE AUTOADMINISTRARSE EL MEDICAMENTO DE FORMA AMBULATORIA PARA TRATAR EL DOLOR O LA ADICION A UNA SUBSTANCIA. ADEMAS ES IMPORTANTE EL HECHO DE QUE LA ADMINISTRACION DE KETAMINA MEDIANTE SPRAYS NASALES O INHALADORES ES GENERALMENTE BIEN ACEPTADA SOCIALMENTE. ASI, POR EJEMPLO, UN PACIENTE QUE SUFRIA UN INSOPORTABLE DOLOR DE VESICULA QUE ERA INTRATABLE, CONSIGUIO CONTROLAR ESTE ATAQUE DE DOLOR CON LA ADMINISTRACION DE UNA DOSIS DE 16 A 32 MG DE KETAMINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/201,756 US5543434A (en) | 1994-02-25 | 1994-02-25 | Nasal administration of ketamine to manage pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2165910T3 true ES2165910T3 (es) | 2002-04-01 |
Family
ID=22747152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95913499T Expired - Lifetime ES2165910T3 (es) | 1994-02-25 | 1995-02-24 | Administracion nasal y ocular de cetamina para el tratamiento del dolor y para la desintoxicacion. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5543434A (es) |
| EP (1) | EP0751766B1 (es) |
| JP (1) | JP4729148B2 (es) |
| AT (1) | ATE206913T1 (es) |
| CA (1) | CA2184077C (es) |
| DE (1) | DE69523295T2 (es) |
| DK (1) | DK0751766T3 (es) |
| ES (1) | ES2165910T3 (es) |
| MX (1) | MX9603633A (es) |
| PT (1) | PT751766E (es) |
| WO (1) | WO1995022965A2 (es) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5679714A (en) * | 1995-06-07 | 1997-10-21 | Weg; Stuart L. | Administration of ketamine for detoxification and treatment of tobacco addiction |
| ATE245024T1 (de) * | 1995-02-24 | 2003-08-15 | Stuart L Weg | Anwendung von ketamin zur entgiftung |
| US5496537A (en) * | 1995-03-23 | 1996-03-05 | Henry; Richard A. | Propofol hydrofluorocarbon propellant formulations |
| CA2230690C (en) * | 1995-08-30 | 2008-12-23 | Stuart L. Weg | Administration of ketamine to manage pain and to reduce drug dependency |
| US6197830B1 (en) * | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| US5976573A (en) * | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
| US6248789B1 (en) | 1996-08-29 | 2001-06-19 | Stuart L. Weg | Administration of ketamine to manage pain and to reduce drug dependency |
| GB9707934D0 (en) * | 1997-04-18 | 1997-06-04 | Danbiosyst Uk | Improved delivery of drugs to mucosal surfaces |
| US20040034107A1 (en) * | 1999-02-11 | 2004-02-19 | Mse Pharmazeutika Gmbh | Ubiquinone Qn for the treatment of pain |
| EP1103256A1 (de) * | 1999-11-26 | 2001-05-30 | Claudius Dr. med. Böck | Verwendung von Ketamin zur Behandlung von neuroendokriner Immundysfunktion und algogenem Psychosyndrom |
| WO2002011778A1 (en) * | 2000-05-10 | 2002-02-14 | University Of Kentucky Research Foundation | System and method for intranasal administration of opioids |
| US20060083691A1 (en) * | 2000-05-10 | 2006-04-20 | Wermeling Daniel P | Intranasal opioid compositions, delivery devices and methods of using same |
| US6610271B2 (en) * | 2000-05-10 | 2003-08-26 | University Of Kentucky Research Foundation | System and method for intranasal administration of lorazepam |
| US20040115133A1 (en) * | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
| ES2302742T5 (es) * | 2000-07-31 | 2011-10-10 | Nycomed Danmark Aps | Pulverizador nasal para suministrar una composición farmacéutica. |
| WO2002013886A2 (en) * | 2000-08-15 | 2002-02-21 | University Of Kentucky Research Foundation | Programmable multi-dose intranasal drug delivery device |
| US20020106407A1 (en) * | 2000-12-11 | 2002-08-08 | Dennis Coleman | Method and apparatus for treating breakthrough pain |
| US20040176359A1 (en) * | 2001-02-20 | 2004-09-09 | University Of Kentucky Research Foundation | Intranasal Benzodiazepine compositions |
| US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
| US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
| US6805853B2 (en) * | 2001-11-09 | 2004-10-19 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
| US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
| US7090830B2 (en) | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
| US7585493B2 (en) | 2001-05-24 | 2009-09-08 | Alexza Pharmaceuticals, Inc. | Thin-film drug delivery article and method of use |
| JP4357842B2 (ja) * | 2001-05-24 | 2009-11-04 | アレックザ ファーマシューティカルズ, インコーポレイテッド | 所定の吸入ルートによるアルプラゾラム、エスタゾラム、ミダゾラムまたはトリアゾラムの送出 |
| JP2005503425A (ja) * | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
| US7766013B2 (en) | 2001-06-05 | 2010-08-03 | Alexza Pharmaceuticals, Inc. | Aerosol generating method and device |
| CN1551770A (zh) | 2001-07-06 | 2004-12-01 | ������ҩ������˾ | 羟吗啡酮控释制剂 |
| US8329216B2 (en) | 2001-07-06 | 2012-12-11 | Endo Pharmaceuticals Inc. | Oxymorphone controlled release formulations |
| BR0205722A (pt) * | 2001-07-06 | 2005-04-05 | Penwest Pharmaceuticals Compan | Formulação de liberação prolongada e método para o tratamento de um paciente que sofre de dor |
| WO2003026743A2 (en) * | 2001-09-26 | 2003-04-03 | Penwest Pharmaceuticals Company | Opioid formulations having reduced potential for abuse |
| WO2003051367A1 (en) * | 2001-12-18 | 2003-06-26 | Alexza Molecular Delivery Corporation | Parental analgesic formulations comprising fentanyl and a cannabinoid receptor agonist |
| US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| US7273889B2 (en) * | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| CA2506615A1 (en) | 2002-11-18 | 2004-06-03 | Yaupon Therapeutics, Inc. | Analgesic uses of norketamine and ketamine/norketamine prodrugs |
| US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
| US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
| GB0300531D0 (en) * | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
| US20040213828A1 (en) * | 2003-04-23 | 2004-10-28 | Smith David J. | Pain relief lollipop compositions and methods |
| EP1625334B9 (en) | 2003-05-21 | 2012-07-25 | Alexza Pharmaceuticals, Inc. | Percussively ignited self-contained heating unit |
| JP2007509115A (ja) * | 2003-10-21 | 2007-04-12 | ソセイ・アール・アンド・ディー・リミテッド | オピエートの増強のための非オピエートの使用 |
| GB0400804D0 (en) | 2004-01-14 | 2004-02-18 | Innoscience Technology Bv | Pharmaceutical compositions |
| US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
| WO2006022714A1 (en) | 2004-08-12 | 2006-03-02 | Alexza Pharmaceuticals, Inc. | Aerosol drug delivery device incorporating percussively activated heat packages |
| GB0523031D0 (en) * | 2005-11-11 | 2005-12-21 | Yaupon Therapeutics | Enhancement of morphine analgesia by s(-)-norketamine |
| US20070212414A1 (en) * | 2006-03-08 | 2007-09-13 | Penwest Pharmaceuticals Co. | Ethanol-resistant sustained release formulations |
| WO2007111880A2 (en) * | 2006-03-22 | 2007-10-04 | Mount Sinai School Of Medicine | Intranasal administration of ketamine to treat depression |
| US20080275030A1 (en) * | 2007-01-19 | 2008-11-06 | Sveinbjorn Gizurarson | Methods and Compositions for the Delivery of a Therapeutic Agent |
| WO2008112661A2 (en) | 2007-03-09 | 2008-09-18 | Alexza Pharmaceuticals, Inc. | Heating unit for use in a drug delivery device |
| WO2009103150A1 (en) * | 2008-02-20 | 2009-08-27 | Kevin David Smith | Method for treating migraine headaches |
| US20110038807A1 (en) * | 2009-08-14 | 2011-02-17 | Demitri Papolos | Compositions and methods for treating bipolar disorder |
| KR20150096370A (ko) | 2012-08-23 | 2015-08-24 | 스튜어트 엘. 웨그 | 항불안제 조성물, 제형 및 사용방법 |
| CN111643449A (zh) | 2013-03-15 | 2020-09-11 | 詹森药业有限公司 | S-盐酸氯胺酮的药物组合物 |
| CA2909357C (en) | 2013-04-12 | 2022-02-22 | Icahn School Of Medicine At Mount Sinai | Use of ketamine to treat post-traumatic stress disorder |
| PL3043785T3 (pl) | 2013-09-13 | 2022-02-28 | National University Corporation Chiba University | Zastosowanie R-ketaminy i jej soli jako środków farmaceutycznych |
| CN106714789A (zh) | 2014-08-13 | 2017-05-24 | 詹森药业有限公司 | 用于治疗抑郁症的方法 |
| JP2017528483A (ja) | 2014-09-15 | 2017-09-28 | ヤンセン ファーマシューティカ エヌ.ベー. | Val66Met(SNP rs6265)遺伝子型特異的投薬レジメン及びうつ病の治療のための方法 |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| US20200297734A1 (en) | 2015-06-19 | 2020-09-24 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| AU2016280161B2 (en) * | 2015-06-19 | 2019-02-21 | Harrow Ip, Llc | Pharmaceutical compositions for anesthesiological applications |
| US10179136B2 (en) | 2015-06-19 | 2019-01-15 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US10555952B2 (en) | 2015-06-19 | 2020-02-11 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US10391102B2 (en) | 2015-06-19 | 2019-08-27 | Melt Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US10166240B2 (en) | 2015-06-19 | 2019-01-01 | Imprimis Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for anesthesiological applications |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| BR112020012473A2 (pt) | 2017-12-22 | 2020-11-24 | Janssen Pharmaceuticals, Inc. | escetamina para o tratamento da depressão |
| WO2019152873A1 (en) | 2018-02-02 | 2019-08-08 | Alexza Pharmaceuticals, Inc. | Electrical condensation aerosol device |
| EP3753557B1 (en) | 2018-02-15 | 2025-11-05 | National University Corporation Chiba University | Preventive or therapeutic agent and pharmaceutical composition for inflammatory diseases or bone diseases |
| JP2021523228A (ja) | 2018-05-04 | 2021-09-02 | パーセプション ニューロサイエンス,インコーポレイティド | 物質乱用の治療方法 |
| US11154537B2 (en) | 2018-08-10 | 2021-10-26 | Eleusis Therapeutics Us, Inc. | Method of treatment for ketamine infusion |
| BR112021017457A2 (pt) | 2019-03-05 | 2021-11-16 | Janssen Pharmaceuticals Inc | Escetamina para o tratamento de depressão |
| EP3976012B1 (en) | 2019-05-31 | 2024-03-20 | Afyx Therapeutics A/S | Intranasal administration of ketamine to cluster headache patients |
| US11160799B2 (en) * | 2019-10-22 | 2021-11-02 | Cessatech A/S | Pediatric combination |
| EP4093388A1 (en) | 2020-01-22 | 2022-11-30 | Seelos Therapeutics, Inc. | Reducing side effects of nmda antagonists |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4334526A (en) * | 1979-05-24 | 1982-06-15 | Hamacher Edward N | Method for administering a dissociative, unconscious type of anesthesia |
| US5132114A (en) * | 1985-05-01 | 1992-07-21 | University Of Utah Research Foundation | Compositions and methods of manufacture of compressed powder medicaments |
| US4671953A (en) * | 1985-05-01 | 1987-06-09 | University Of Utah Research Foundation | Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics |
| US5112804A (en) * | 1987-04-01 | 1992-05-12 | Temple University Of The Commonwealth System Of Higher Education | Pharmaceutical composition and method of intranasal administration |
| GB9202464D0 (en) * | 1992-02-05 | 1992-03-18 | Danbiosyst Uk | Composition for nasal administration |
-
1994
- 1994-02-25 US US08/201,756 patent/US5543434A/en not_active Expired - Lifetime
-
1995
- 1995-02-24 DK DK95913499T patent/DK0751766T3/da active
- 1995-02-24 PT PT95913499T patent/PT751766E/pt unknown
- 1995-02-24 JP JP52250695A patent/JP4729148B2/ja not_active Expired - Fee Related
- 1995-02-24 ES ES95913499T patent/ES2165910T3/es not_active Expired - Lifetime
- 1995-02-24 EP EP95913499A patent/EP0751766B1/en not_active Expired - Lifetime
- 1995-02-24 DE DE69523295T patent/DE69523295T2/de not_active Expired - Lifetime
- 1995-02-24 AT AT95913499T patent/ATE206913T1/de active
- 1995-02-24 CA CA002184077A patent/CA2184077C/en not_active Expired - Fee Related
- 1995-02-24 WO PCT/US1995/002418 patent/WO1995022965A2/en not_active Ceased
-
1996
- 1996-08-23 MX MX9603633A patent/MX9603633A/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DK0751766T3 (da) | 2002-02-11 |
| WO1995022965A2 (en) | 1995-08-31 |
| MX9603633A (es) | 1998-01-31 |
| US5543434A (en) | 1996-08-06 |
| EP0751766A1 (en) | 1997-01-08 |
| CA2184077C (en) | 2007-12-11 |
| EP0751766B1 (en) | 2001-10-17 |
| DE69523295D1 (de) | 2001-11-22 |
| ATE206913T1 (de) | 2001-11-15 |
| DE69523295T2 (de) | 2002-07-11 |
| PT751766E (pt) | 2002-04-29 |
| JPH10500664A (ja) | 1998-01-20 |
| WO1995022965A3 (en) | 1995-12-21 |
| JP4729148B2 (ja) | 2011-07-20 |
| CA2184077A1 (en) | 1995-08-31 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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