[go: up one dir, main page]

ES2156725B1 - DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING. - Google Patents

DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Info

Publication number
ES2156725B1
ES2156725B1 ES9900954A ES9900954A ES2156725B1 ES 2156725 B1 ES2156725 B1 ES 2156725B1 ES 9900954 A ES9900954 A ES 9900954A ES 9900954 A ES9900954 A ES 9900954A ES 2156725 B1 ES2156725 B1 ES 2156725B1
Authority
ES
Spain
Prior art keywords
fused
derivatives
dioxides
procedure
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9900954A
Other languages
Spanish (es)
Other versions
ES2156725A1 (en
Inventor
Gil Ana Martinez
Ayuso-Gontan Carmen Gil
Castro Ana Morera
Martin M Concepcion Perez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Priority to ES9900954A priority Critical patent/ES2156725B1/en
Priority to AU44063/00A priority patent/AU4406300A/en
Priority to PCT/ES2000/000165 priority patent/WO2000068216A1/en
Publication of ES2156725A1 publication Critical patent/ES2156725A1/en
Application granted granted Critical
Publication of ES2156725B1 publication Critical patent/ES2156725B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Derivados de dióxidos N,N- y N,X-disustituidos de 1,2,6- tiadiazina fusionadas y procedimiento de obtención. La invención se dirige a los compuestos de fórmula general I, II y III y a su procedimiento de obtención, que se realiza en dos etapas, primeramente los compuestos III y después se obtienen los I y II. Estos compuestos tienen posible aplicación en el campo de las infecciones vírales oportunistas en pacientes inmunocomprometidos.Derivatives of fused N, N- and N, X-disubstituted 1,2,6-thiadiazine dioxides and obtaining procedure. The invention is directed to the compounds of general formula I, II and III and their method of production, which is carried out in two stages, firstly compounds III and then I and II are obtained. These compounds have possible application in the field of opportunistic viral infections in immunocompromised patients.

ES9900954A 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING. Expired - Fee Related ES2156725B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ES9900954A ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.
AU44063/00A AU4406300A (en) 1999-05-07 2000-05-05 Fused 1,2,6-thiadiazine -LTiGTn,nLT/iGT and LTiGTn,xLT/iGT-disubstituted dioxidederivatives and corresponding production method
PCT/ES2000/000165 WO2000068216A1 (en) 1999-05-07 2000-05-05 Fused 1,2,6-thiadiazine -n,n and n,x-disubstituted dioxide derivatives and corresponding production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9900954A ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Publications (2)

Publication Number Publication Date
ES2156725A1 ES2156725A1 (en) 2001-07-01
ES2156725B1 true ES2156725B1 (en) 2002-03-01

Family

ID=8308292

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9900954A Expired - Fee Related ES2156725B1 (en) 1999-05-07 1999-05-07 DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.

Country Status (3)

Country Link
AU (1) AU4406300A (en)
ES (1) ES2156725B1 (en)
WO (1) WO2000068216A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0608928D0 (en) 2006-05-08 2006-06-14 Angeletti P Ist Richerche Bio Therapeutic agents
WO2008073958A2 (en) 2006-12-12 2008-06-19 Wyeth Substituted benzothiadiazinedioxide derivatives and methods of their use
AU2008277440A1 (en) 2007-07-17 2009-01-22 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa Macrocyclic indole derivatives for the treatment of hepatitis C infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2656290A1 (en) * 1976-12-11 1978-06-15 Basf Ag BENZOTHIADIAZINE COMPOUNDS
AU2074699A (en) * 1998-01-26 1999-08-09 Yamanouchi Pharmaceutical Co., Ltd. Novel benzene-fused heterocyclic derivatives or salts thereof

Also Published As

Publication number Publication date
AU4406300A (en) 2000-11-21
WO2000068216A1 (en) 2000-11-16
ES2156725A1 (en) 2001-07-01

Similar Documents

Publication Publication Date Title
CY1109886T1 (en) New compounds as anti-inflammatory, immunomodulatory and anti-hypoplastic agents
CY1105797T1 (en) N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBIOTICS
EA200100826A1 (en) 16-HALOGEN DERIVATIVES OF EPOTHILON, METHOD OF THEIR PRODUCTION AND THEIR APPLICATION IN PHARMACEUTICS
MEP58108A (en) Lactam-containing compounds and their derivatives X Factor Inhibitors
CY1111317T1 (en) 4-PHENYLOPYRIDINE DERIVATIVE AND USE OF THIS AS COMPETITIVE RECEPTORS OF NK-1
ECSP056111A (en) DERIVATIVES OF 2-ACILAMINO-4-FENILTIAZOL, ITS PREPARATION AND APPLICATION IN THERAPEUTICS
ATE556059T1 (en) PYRAZOLE DERIVATIVES FOR THE TREATMENT OF HIV
EA200100412A1 (en) SUBSTITUTED 3-CYANOHINOLINES AS PROTEINTHYROSINKINASE INHIBITORS
CY1114214T1 (en) Lys-Pro-Thr KAI Lys-Pro AS COMPONENTS THAT INFLUENCE INFLAMMATION
EA200600621A1 (en) DERIVATIVES OF TETRAHYDRONAPTALINE, METHOD OF THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY MEANS
CY1110258T1 (en) Substituted C-cyclohexylmethylamine derivatives
ECSP045258A (en) SUBSTITUTED HYDROXIETILAMINS
DE60135919D1 (en) FARNESYL TRANSFERASE-INHIBITING 6-HETEROCYCLYLMETHYL-CHINOLINE AND CHINAZOLE DERIVATIVES
IS6174A (en) New derivatives and analogues of galantamine
DE60121461D1 (en) CONDENSED PYRIDOINDOL DERIVATIVES
ATE345349T1 (en) PURINE DERIVATIVES
SE0203825D0 (en) Novel fused heterocycles and uses thereof
EA200300392A1 (en) Derivatives of piperazine with a bridge connection
MX9306666A (en) NEW AZETIDINONES SUBSTITUTED AS ANTI-INFLAMMATORY AND ANTI-DEGENERATIVE AGENTS.
DE60201084D1 (en) PRODUCTION OF CYCLIC ESTEROLIGOMERS
CY1105939T1 (en) BENZOTHIAZINE AND BENZOTHEADIAZINE DERIVATIVES, METHOD OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
ES2156725B1 (en) DERIVATIVES OF DIOXIDES N, N- AND N, X-DISUSTITUTES OF 1,2,6-TIADIAZINE FUSED AND PROCEDURE OF OBTAINING.
ES2189730T3 (en) AZA-INDOLINIC POLICY DERIVATIVES, THEIR PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
DE60028816D1 (en) Production of unipolar components
CY1107485T1 (en) 3-THYMOMYTHYPYRAZOLES AS PARASIDICIDES

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 20010701

Kind code of ref document: A1

Effective date: 20010701

FD2A Announcement of lapse in spain

Effective date: 20180807