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ES2155528T3 - Procedimiento y dispositivo para la rapida separacion y/o conversion de sustratos. - Google Patents

Procedimiento y dispositivo para la rapida separacion y/o conversion de sustratos.

Info

Publication number
ES2155528T3
ES2155528T3 ES95931184T ES95931184T ES2155528T3 ES 2155528 T3 ES2155528 T3 ES 2155528T3 ES 95931184 T ES95931184 T ES 95931184T ES 95931184 T ES95931184 T ES 95931184T ES 2155528 T3 ES2155528 T3 ES 2155528T3
Authority
ES
Spain
Prior art keywords
substrates
conversion
procedure
compact porous
carrier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95931184T
Other languages
English (en)
Inventor
Djuro Josic
Primoz Koselj
Ales Podgronik
Ales Strancar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Bia Separations doo
Original Assignee
Bia Separations doo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bia Separations doo filed Critical Bia Separations doo
Application granted granted Critical
Publication of ES2155528T3 publication Critical patent/ES2155528T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28042—Shaped bodies; Monolithic structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6069—Construction of the column body with compartments or bed substructure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1892—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns the sorbent material moving as a whole, e.g. continuous annular chromatography, true moving beds or centrifugal chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/32—Control of physical parameters of the fluid carrier of pressure or speed
    • G01N2030/324—Control of physical parameters of the fluid carrier of pressure or speed speed, flow rate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/386—Radial chromatography, i.e. with mobile phase traversing radially the stationary phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/527—Physical parameters structural properties sorbent material in form of a membrane
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Surface Acoustic Wave Elements And Circuit Networks Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

UN PROCEDIMIENTO PARA LA CONVERSION DE SUSTRATOS TANTO PARA PROPOSITOS ANALITICOS COMO PREPARATIVOS EN UN REACTOR DE FLUJO CONTINUO Y CRUZADO QUE TIENE DISCOS POROSOS COMPACTOS Y/O TUBOS POROSOS COMPACTOS COMO PORTADOR PARA REACCION DE CONVERSION O SEPARACIONES PREPARATIVAS; DICHOS DISCOS POROSOS COMPACTOS Y/O TUBOS POROSOS COMPACTOS SON MODIFICADOS CON SUSTANCIAS QUE SON CAPACES DE UNIRSE ESPECIFICAMENTE Y/O CONVERTIR DICHOS SUSTRATOS MEDIANTE DISTRIBUCION DE LAS MUESTRAS A CONVERTIR Y/O PREPARATIVAMENTE SEPARADAS Y RECOGER LOS SUSTRATOS CONVERTIDOS Y/O SEPARADOS PREFERIBLEMENTE EN UN VOLUMEN BAJO, EN DONDE LA DISTRIBUCION DE LA MUESTRA NO AFECTA AL PORTADOR DE FORMA ADVERSA.
ES95931184T 1994-08-23 1995-08-22 Procedimiento y dispositivo para la rapida separacion y/o conversion de sustratos. Expired - Lifetime ES2155528T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94113105 1994-08-23

Publications (1)

Publication Number Publication Date
ES2155528T3 true ES2155528T3 (es) 2001-05-16

Family

ID=8216224

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95931184T Expired - Lifetime ES2155528T3 (es) 1994-08-23 1995-08-22 Procedimiento y dispositivo para la rapida separacion y/o conversion de sustratos.

Country Status (7)

Country Link
US (2) US5972218A (es)
EP (2) EP0777725B1 (es)
AT (1) ATE200303T1 (es)
DE (1) DE69520586T2 (es)
DK (1) DK0777725T3 (es)
ES (1) ES2155528T3 (es)
WO (1) WO1996006158A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0777725B1 (en) * 1994-08-23 2001-04-04 Bia Separations D.O.O. Process and device for the rapid separation and/or conversion of substrates
JP4109418B2 (ja) * 1998-02-27 2008-07-02 ビーアイエー セパレイションズ ディーオーオー 新規なクロマトグラフィー装置
DE19833738A1 (de) * 1998-07-27 2000-02-03 Michael Giesing Verfahren zur Isolierung von Krebszellen aus zellhaltigen Körperflüssigkeiten sowie Sets zur Durchführung dieses Verfahrens
US20040002081A1 (en) * 2001-12-18 2004-01-01 Boehringer Ingelheim International Gmbh And Bia Separations D.O.O. Method and device for isolating and purifying a polynucleotide of interest on a manufacturing scale
US20040104156A1 (en) * 2002-11-26 2004-06-03 Kolesinski Henry S. Chromatographic separation processes and apparatus
AU2003298894A1 (en) * 2002-11-26 2004-06-18 Prime Separations, Incorporated Chromatographic separation processes and apparatus
US20090078628A1 (en) * 2007-09-20 2009-03-26 Stetson Development, Inc. Pool filtration system
WO2009140408A2 (en) 2008-05-13 2009-11-19 University Of Kansas Metal abstraction peptide (map) tag and associated methods
WO2013106337A1 (en) 2012-01-09 2013-07-18 Sanofi Pasteur Biologics, Llc Purification of flaviviruses
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
EP2705899A1 (en) 2012-09-07 2014-03-12 Fluigent A microfluidic system comprising a homogenizing component
US11353433B2 (en) 2016-08-26 2022-06-07 Puridify Ltd. Chromatography system
JP2022513594A (ja) 2018-11-06 2022-02-09 アルヘル プロジェクティランジェ イン インゼニリング ディー．オー．オー． 乳、初乳及び酸性又は甘性ホエーから高度に精製されたラクトフェリン及びラクトペルオキシダーゼを製造する方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3308558A (en) * 1964-05-14 1967-03-14 Michael D Orlando Environmental chamber
US3483990A (en) * 1967-03-06 1969-12-16 Beckman Instruments Inc Dialyzer apparatus
FR2129164A5 (es) * 1971-03-17 1972-10-27 Rhone Poulenc Sa
CA1056746A (en) * 1974-09-06 1979-06-19 Chung J. Lai Biologically active membrane material
IT1087106B (it) * 1977-10-13 1985-05-31 Snam Progetti Reattore radiale per catalisi enzimatica
US4202774A (en) * 1978-05-24 1980-05-13 Dorr-Oliver Incorporated Flow distributor for fluid bed biological reactor
DE2967343D1 (en) * 1978-09-06 1985-02-14 Fujisawa Pharmaceutical Co Immobilized enzyme column
US4963264A (en) * 1985-06-10 1990-10-16 The Standard Oil Company Process for selective dialysis using polymeric affinity adsorbents and size selective membranes
GB2201904B (en) * 1987-02-14 1990-12-19 Domnick Hunter Filters Ltd Device for liquid chromatography or immobilised enzyme reaction
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
JP2543728B2 (ja) * 1987-11-13 1996-10-16 株式会社ミドリ十字 返還用自己血の処理装置
DE3811099A1 (de) * 1988-03-31 1989-10-12 Biometra Biomedizinische Analy Verfahren zum nachweis von verbindungen, die katalysiert durch oxidase elektronen aufnehmen oder abgeben koennen
DK162191C (da) * 1989-09-15 1992-02-17 Eskofot As Filter til filtrering af vaesker
US5310526A (en) * 1990-10-30 1994-05-10 The Dow Chemical Company Chemical sensor
US5183569A (en) * 1991-12-16 1993-02-02 Paradigm Biotechnologies Partnership Filtration apparatus and process
EP0777725B1 (en) * 1994-08-23 2001-04-04 Bia Separations D.O.O. Process and device for the rapid separation and/or conversion of substrates

Also Published As

Publication number Publication date
US5972218A (en) 1999-10-26
EP0777725A1 (en) 1997-06-11
WO1996006158A1 (en) 1996-02-29
US6319401B1 (en) 2001-11-20
EP1101817A1 (en) 2001-05-23
DE69520586T2 (de) 2001-11-15
DK0777725T3 (da) 2001-08-06
DE69520586D1 (de) 2001-05-10
ATE200303T1 (de) 2001-04-15
EP0777725B1 (en) 2001-04-04

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