ES2039272T3 - Sales opticamente activas a base de un tiazolidin-4-carboxilato sustituido y 3-cloro-2-hidroxipropiltrimetilamonio, su preparacion y empleo. - Google Patents
Sales opticamente activas a base de un tiazolidin-4-carboxilato sustituido y 3-cloro-2-hidroxipropiltrimetilamonio, su preparacion y empleo.Info
- Publication number
- ES2039272T3 ES2039272T3 ES198888113190T ES88113190T ES2039272T3 ES 2039272 T3 ES2039272 T3 ES 2039272T3 ES 198888113190 T ES198888113190 T ES 198888113190T ES 88113190 T ES88113190 T ES 88113190T ES 2039272 T3 ES2039272 T3 ES 2039272T3
- Authority
- ES
- Spain
- Prior art keywords
- optically active
- preparation
- carboxylate
- chlorine
- active salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical class OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 title 1
- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- LTVDFSLWFKLJDQ-UHFFFAOYSA-N α-tocopherolquinone Chemical compound CC(C)CCCC(C)CCCC(C)CCCC(C)(O)CCC1=C(C)C(=O)C(C)=C(C)C1=O LTVDFSLWFKLJDQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/40—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
LA PATENTE AFECTA A LA PRODUCCION DE SALES OPTICAMENTE ACTIVAS DE FORMULA GENERAL DE LAS QUE SE PUEDE OBTENER MEDIANTE SEPARACION DE ACIDOS EL 3 - CLORO - 2 - HIDROXIPROPILTRIMETILAMONIOCLORURO OPTICAMENTE ACTIVO. LA FORMA L(-) DE ESTE COMPUESTO ES UN ELEMENTO VALIOSO PARA LA SINTESIS DE L(-)CARNITINA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873735757 DE3735757A1 (de) | 1987-10-22 | 1987-10-22 | Optisch aktive salze aus einem substituierten thiazolidin-4-carboxylat und 3-chlor-2-hydroxypropyltrimethylammonium, deren herstellung und verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2039272T3 true ES2039272T3 (es) | 1993-09-16 |
Family
ID=6338854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888113190T Expired - Lifetime ES2039272T3 (es) | 1987-10-22 | 1988-08-13 | Sales opticamente activas a base de un tiazolidin-4-carboxilato sustituido y 3-cloro-2-hidroxipropiltrimetilamonio, su preparacion y empleo. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4914208A (es) |
| EP (1) | EP0312726B1 (es) |
| JP (1) | JPH01135747A (es) |
| AT (1) | ATE74598T1 (es) |
| DE (2) | DE3735757A1 (es) |
| ES (1) | ES2039272T3 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4015573A1 (de) * | 1990-05-15 | 1991-11-21 | Degussa | Optisch aktive salze aus einem substituierten thiazolidin-4-carboxylat und 3-cyano-2-hydroxypropyltrimethylammonium, deren herstellung und verwendung |
| DE4111913A1 (de) * | 1991-04-12 | 1992-10-15 | Degussa | Verfahren zur herstellung von l-carnitin aus d,l-carnitinnitrilsalzen |
| US6083966A (en) * | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
| CA2344913A1 (en) * | 1998-09-21 | 2000-03-30 | University Of Florida Research Foundation, Inc. | Antimalarial agents |
| AU2003263948A1 (en) * | 2002-08-22 | 2004-03-11 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| US20040044220A1 (en) * | 2002-08-22 | 2004-03-04 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| AU2003270473A1 (en) * | 2003-09-09 | 2005-04-27 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
| PL1866296T3 (pl) | 2005-04-04 | 2017-05-31 | University Of Florida Research Foundation, Inc. | Polieterowe analogi desferritiocyny |
| US8324397B2 (en) | 2007-03-15 | 2012-12-04 | University Of Florida Research Foundation, Inc. | Desferrithiocin polyether analogues |
| ES2761200T3 (es) | 2011-12-16 | 2020-05-19 | Univ Florida | Usos de análogos de 4'-desferritiocina |
| CN102807495A (zh) * | 2012-08-22 | 2012-12-05 | 中国林业科学研究院林产化学工业研究所 | 3-氯-2-羟丙基二甲基脱氢枞基氯化铵及其制备方法 |
| EP3071201A4 (en) | 2013-11-22 | 2017-04-26 | University of Florida Research Foundation, Inc. | Desferrithiocin analogs and uses thereof |
| AU2016255770A1 (en) | 2015-04-27 | 2017-11-16 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947464A (en) * | 1972-07-28 | 1976-03-30 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Salts of phenylpropanolamine with thiazolidine carboxylic acids |
| CH658857A5 (de) * | 1984-04-04 | 1986-12-15 | Lonza Ag | Optisch aktives di-(3-chlor-2-oxy-propyltrimethylammonium)-tartrat. |
| JPH0692188B2 (ja) * | 1986-01-08 | 1994-11-16 | 三菱油化株式会社 | 水性インク記録用シ−ト |
-
1987
- 1987-10-22 DE DE19873735757 patent/DE3735757A1/de not_active Withdrawn
-
1988
- 1988-08-13 EP EP88113190A patent/EP0312726B1/de not_active Expired - Lifetime
- 1988-08-13 ES ES198888113190T patent/ES2039272T3/es not_active Expired - Lifetime
- 1988-08-13 DE DE8888113190T patent/DE3869898D1/de not_active Expired - Lifetime
- 1988-08-13 AT AT88113190T patent/ATE74598T1/de not_active IP Right Cessation
- 1988-10-17 US US07/262,722 patent/US4914208A/en not_active Expired - Fee Related
- 1988-10-20 JP JP63263039A patent/JPH01135747A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0312726A1 (de) | 1989-04-26 |
| DE3869898D1 (de) | 1992-05-14 |
| JPH01135747A (ja) | 1989-05-29 |
| US4914208A (en) | 1990-04-03 |
| DE3735757A1 (de) | 1989-05-03 |
| ATE74598T1 (de) | 1992-04-15 |
| EP0312726B1 (de) | 1992-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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