ES2023778A6 - Process for preparing alkaline salts of omeprazole - Google Patents
Process for preparing alkaline salts of omeprazoleInfo
- Publication number
- ES2023778A6 ES2023778A6 ES9003174A ES9003174A ES2023778A6 ES 2023778 A6 ES2023778 A6 ES 2023778A6 ES 9003174 A ES9003174 A ES 9003174A ES 9003174 A ES9003174 A ES 9003174A ES 2023778 A6 ES2023778 A6 ES 2023778A6
- Authority
- ES
- Spain
- Prior art keywords
- omeprazole
- alkaline salts
- preparing alkaline
- formula
- alkaline salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical class N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 title abstract 4
- 229960000381 omeprazole Drugs 0.000 title abstract 4
- 159000000011 group IA salts Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Process for obtaining an alkaline salt of omeprazole of formula I < IMAGE > (M=Li, Na or K), in which omeprazole is caused to react with an alkaline salt of an active methylene of formula [Z - CH - Z'] M+ where Z and Z' are strong acceptor groups, which may or may not be the same, and M has the meaning indicated above. These salts have a lesser degree of decomposition and greater solubility than omeprazole, which is a very effective drug for the treatment of gastric ulcers.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003174A ES2023778A6 (en) | 1990-12-12 | 1990-12-12 | Process for preparing alkaline salts of omeprazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9003174A ES2023778A6 (en) | 1990-12-12 | 1990-12-12 | Process for preparing alkaline salts of omeprazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2023778A6 true ES2023778A6 (en) | 1992-02-01 |
Family
ID=8270014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9003174A Expired - Lifetime ES2023778A6 (en) | 1990-12-12 | 1990-12-12 | Process for preparing alkaline salts of omeprazole |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2023778A6 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1186602A3 (en) * | 1997-06-26 | 2002-03-27 | AstraZeneca AB | Omeprazole sodium salt and its use as anti-ulcer agent |
-
1990
- 1990-12-12 ES ES9003174A patent/ES2023778A6/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1186602A3 (en) * | 1997-06-26 | 2002-03-27 | AstraZeneca AB | Omeprazole sodium salt and its use as anti-ulcer agent |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted |
Owner name: ESTEVE QUIMICA, S.A. |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20110225 |