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ES2018959A6 - Metodo de delineacion de cromosomas humanos individuales en celulas metafasicas e interfasicas mediante hibridacion de suspension in situ. - Google Patents

Metodo de delineacion de cromosomas humanos individuales en celulas metafasicas e interfasicas mediante hibridacion de suspension in situ.

Info

Publication number
ES2018959A6
ES2018959A6 ES8903888A ES8903888A ES2018959A6 ES 2018959 A6 ES2018959 A6 ES 2018959A6 ES 8903888 A ES8903888 A ES 8903888A ES 8903888 A ES8903888 A ES 8903888A ES 2018959 A6 ES2018959 A6 ES 2018959A6
Authority
ES
Spain
Prior art keywords
uses therefor
chromosomes
hybridization
situ suppression
situ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8903888A
Other languages
English (en)
Inventor
David C Ward
Peter Lichter
Thomas Cremer
Laura Manuelidis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23036299&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2018959(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yale University filed Critical Yale University
Publication of ES2018959A6 publication Critical patent/ES2018959A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE DELINEACION DE CROMOSOMAS HUMANOS INDIVIDUALES EN CELULAS METAFASICAS E INTERFASICAS MEDIANTE HIBRIDACION DE SUPRESION IN SITU, EN CONCRETO PARA DECORAR ESPECIFICAMENTE CROMOSOMAS DE MAMIFEROS SELECCIONADOS Y PARA DETECTAR, IDENTIFICAR Y/O CUANTIFICAR CROMOSOMAS INDIVIDUALES SELECCIONADOS. COMPRENDE LLEVAR A CABO UNA HIDRIDACION CROMOSOMICA DE SUPRESION IN SITU. EL METODO ES DE APLICACION EN EL ANALISIS DE CELULAS RESPECTO A LA PRESENCIA DE CROMOSOMAS, FRAGMENTOS CROMOSOMICOS O ABERRACIONES CROMOSOMICAS.
ES8903888A 1988-11-15 1989-11-15 Metodo de delineacion de cromosomas humanos individuales en celulas metafasicas e interfasicas mediante hibridacion de suspension in situ. Expired - Lifetime ES2018959A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27160988A 1988-11-15 1988-11-15

Publications (1)

Publication Number Publication Date
ES2018959A6 true ES2018959A6 (es) 1991-05-16

Family

ID=23036299

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8903888A Expired - Lifetime ES2018959A6 (es) 1988-11-15 1989-11-15 Metodo de delineacion de cromosomas humanos individuales en celulas metafasicas e interfasicas mediante hibridacion de suspension in situ.

Country Status (10)

Country Link
EP (1) EP0444115B2 (es)
JP (2) JP3871066B2 (es)
CN (1) CN1046392A (es)
AT (1) ATE141957T1 (es)
AU (1) AU4642089A (es)
CA (1) CA2003051C (es)
DE (1) DE68927059T3 (es)
ES (1) ES2018959A6 (es)
IL (1) IL92323A (es)
WO (1) WO1990005789A1 (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985549A (en) * 1985-10-22 1999-11-16 University Of Massachusetts Non-isotopic in-situ hybridization method for detection of nucleic acids
US6280929B1 (en) 1986-01-16 2001-08-28 The Regents Of The University Of California Method of detecting genetic translocations identified with chromosomal abnormalities
US7115709B1 (en) 1986-01-16 2006-10-03 The Regents Of The University Of California Methods of staining target chromosomal DNA employing high complexity nucleic acid probes
US6475720B1 (en) 1986-01-16 2002-11-05 The Regents Of The University Of California Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
US5756696A (en) 1986-01-16 1998-05-26 Regents Of The University Of California Compositions for chromosome-specific staining
US6872817B1 (en) 1986-01-16 2005-03-29 The Regents Of The Univ. Of California Method of staining target interphase chromosomal DNA
US5447841A (en) 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5721098A (en) * 1986-01-16 1998-02-24 The Regents Of The University Of California Comparative genomic hybridization
US6242184B1 (en) 1988-10-18 2001-06-05 University Of Massachusetts In-situ hybridization of single-copy and multiple-copy nucleic acid sequences
US6919211B1 (en) 1989-06-07 2005-07-19 Affymetrix, Inc. Polypeptide arrays
US6955915B2 (en) 1989-06-07 2005-10-18 Affymetrix, Inc. Apparatus comprising polymers
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US8592155B2 (en) 1989-07-19 2013-11-26 The Regents Of The University Of California Method of detecting genetic deletions identified with chromosomal abnormalities
AU647741B2 (en) * 1989-12-01 1994-03-31 Regents Of The University Of California, The Methods and compositions for chromosome-specific staining
US6277569B1 (en) 1990-09-20 2001-08-21 Vysis, Inc. Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization
US5512433A (en) * 1990-11-08 1996-04-30 Vysis, Inc. Methods and compounds for labeling DNA with xanthine and lower alkyl substituted xanthine derivatives and reagents for the in situ detection of chromosomes
AU9178491A (en) * 1990-12-13 1992-07-08 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
US5538869A (en) * 1990-12-13 1996-07-23 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
CA2060267A1 (en) * 1991-02-22 1992-08-23 Joe W. Gray Chromosome specific staining to detect genetic rearrangements
US6025126A (en) 1991-10-28 2000-02-15 Arch Development Corporation Methods and compositions for the detection of chromosomal aberrations
US6849462B1 (en) 1991-11-22 2005-02-01 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US7534567B2 (en) 1992-03-04 2009-05-19 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
US5856097A (en) * 1992-03-04 1999-01-05 The Regents Of The University Of California Comparative genomic hybridization (CGH)
ES2161715T3 (es) 1992-03-04 2001-12-16 Univ California Hibridacion genomica comparativa (hgc).
EP0635067A1 (en) * 1992-04-09 1995-01-25 Ig Laboratories Inc. Probes for detecting common liveborn chromosomal aneuploidies
AU5355594A (en) * 1992-10-09 1994-05-09 Oncor, Inc. Methods for the detection of chromosome structural abnormalities by (in situ) hybridization to fixed tissue
US6277606B1 (en) 1993-11-09 2001-08-21 Cold Spring Harbor Laboratory Representational approach to DNA analysis
US5436142A (en) * 1992-11-12 1995-07-25 Cold Spring Harbor Laboratory Methods for producing probes capable of distingushing variant genomic sequences
US5472842A (en) * 1993-10-06 1995-12-05 The Regents Of The University Of California Detection of amplified or deleted chromosomal regions
US7323298B1 (en) 1994-06-17 2008-01-29 The Board Of Trustees Of The Leland Stanford Junior University Microarray for determining the relative abundances of polynuceotide sequences
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US7049424B2 (en) 1996-07-15 2006-05-23 The Regents Of The University Of California Genes from the 20Q13 amplicon and their uses
US5801021A (en) * 1995-10-20 1998-09-01 The Regents Of The University Of California Amplifications of chromosomal region 20q13 as a prognostic indicator in breast cancer
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
US5792610A (en) * 1996-05-01 1998-08-11 Biorad Laboratories, Inc. Method for conducting multiparametric fluorescence in situ hybridization
US5759781A (en) * 1995-12-22 1998-06-02 Yale University Multiparametric fluorescence in situ hybridization
US6007994A (en) 1995-12-22 1999-12-28 Yale University Multiparametric fluorescence in situ hybridization
EP0878552A1 (en) 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US6043039A (en) * 1998-02-17 2000-03-28 Applied Spectral Imaging Method of and composite for in situ fluorescent hybridization
WO1999057309A1 (en) 1998-05-04 1999-11-11 Dako A/S Method and probes for the detection of chromosome aberrations
DE10037506A1 (de) * 2000-08-01 2002-02-14 Giesing Michael Verfahren zum Nachweis von Nukleinsäuren mittels Hybridisierung, Verwendung dieses Verfahrens und entsprechender Analysekit sowie Nukleinsäure-Oligomere und deren Verwendung
US6956695B2 (en) 2001-03-19 2005-10-18 Ikonisys, Inc. System and method for increasing the contrast of an image produced by an epifluorescence microscope
US7585964B2 (en) 2001-05-14 2009-09-08 Cancer Genetics, Inc. Methods of analyzing chromosomal translocations using fluorescence in situ hybridization (FISH)
JP2005524384A (ja) 2001-09-24 2005-08-18 ボストン　プローブス，インコーポレイテッド ゲノム核酸におけるランダム分布反復配列への検出可能なプローブ結合の抑制に関する方法、キットおよび組成物
AU2003277153A1 (en) 2002-09-27 2004-04-19 The General Hospital Corporation Microfluidic device for cell separation and uses thereof
WO2005079474A2 (en) 2004-02-17 2005-09-01 The Regents Of The University Of California Detection of nucleic acid sequence differences by comparative genomic hybridization
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
EP3109324B1 (de) * 2015-06-23 2018-09-19 ZytoVision GmbH Verfahren zur detektion von chromosomenaberrationen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0261172A1 (en) * 1986-02-21 1988-03-30 Whitehead Institute For Biomedical Research Y-specific dna hybridization probes and uses therefor
NZ221410A (en) * 1986-08-12 1989-11-28 Univ Australian Sex determination in ruminants using y-chromosome specific polynucleotides
US5064948A (en) * 1988-02-12 1991-11-12 The United States Of America As Represented By The Department Of Energy Chromosome specific repetitive dna sequences

Also Published As

Publication number Publication date
JP3871066B2 (ja) 2007-01-24
EP0444115A1 (en) 1991-09-04
DE68927059D1 (de) 1996-10-02
JP2005245452A (ja) 2005-09-15
DE68927059T3 (de) 2001-05-10
CA2003051C (en) 2004-03-02
AU4642089A (en) 1990-06-12
EP0444115B2 (en) 2000-12-13
WO1990005789A1 (en) 1990-05-31
DE68927059T2 (de) 1997-01-30
IL92323A0 (en) 1990-07-26
JPH04502855A (ja) 1992-05-28
CN1046392A (zh) 1990-10-24
IL92323A (en) 1995-10-31
ATE141957T1 (de) 1996-09-15
EP0444115B1 (en) 1996-08-28
CA2003051A1 (en) 1990-05-15

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2009-11-15

FD1A Patent lapsed

Effective date: 20100803