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ES2016441A6 - Un procedimiento para producir 1,1 -ciclobutanodicarboxilato (2-aminometilpirrolidin) platino ii, y sus derivados opticamente activos. - Google Patents

Un procedimiento para producir 1,1 -ciclobutanodicarboxilato (2-aminometilpirrolidin) platino ii, y sus derivados opticamente activos.

Info

Publication number
ES2016441A6
ES2016441A6 ES8901207A ES8901207A ES2016441A6 ES 2016441 A6 ES2016441 A6 ES 2016441A6 ES 8901207 A ES8901207 A ES 8901207A ES 8901207 A ES8901207 A ES 8901207A ES 2016441 A6 ES2016441 A6 ES 2016441A6
Authority
ES
Spain
Prior art keywords
aminomethylpyrrolidine
optically active
active derivatives
platinum
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8901207A
Other languages
English (en)
Inventor
Masahiro Kato
Horohito Shimizu
Tadao Michishita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES2016441A6 publication Critical patent/ES2016441A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/04—Saturated compounds having a carboxyl group bound to a three or four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

UN PROCEDIMIENTO PARA PRODUCIR 1,1-CICLOBUTANODICARBOXILATO (2-AMINOMETILPIRROLIDIN)PLATINO II, Y SUS DERIVADOS OPTICAMENTE ACTIVOS. COMPRENDE: A) HACER REACCIONAR MSI2PTXSI6 (M = SODIO O POTASIO Y X = ATOMO DE HALOGENO) CON 2-AMINOMETILPIRROLIDINA SEGUIDAMENTE CON OXALATO DE PLATA, DESPUES CON LA SAL DE CALCIO DE ACIDO 1,1-CICLOBUTANODICARBOXILICO PARA PRODUCIR (1); O B) HACER REACCIONAR MSI2PTXSI6 (M = SODIO O POTASIO Y X = ATOMO DE HALOGENOS) CON 2-AMINOMETILPIRROLIDINA Y DESPUES CON LA SAL DE PLATA DEL ACIDO 1,1-CICLOBUTANODICARBOXILICO SEGUIDO DE REDUCCION PARA DARA (1); O C) HACER REACCIONAR 2-AMINOMETILPIRROLIDINA CON KSI2PTCLSI4 SEGUIDAMENTE, CON LA SAL DE PLATA DEL ACIDO 1,1-CICLOBUTANODICARBOXILICO PARA DAR (1). EL COMPUESTO (1) Y SUS DERIVADOS OPTICAMENTE ACTIVOS SON UTILES COMO AGENTES ANTICANCEROSOS.
ES8901207A 1988-04-07 1989-04-06 Un procedimiento para producir 1,1 -ciclobutanodicarboxilato (2-aminometilpirrolidin) platino ii, y sus derivados opticamente activos. Expired - Lifetime ES2016441A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8559588 1988-04-07
JP8559488 1988-04-07

Publications (1)

Publication Number Publication Date
ES2016441A6 true ES2016441A6 (es) 1990-11-01

Family

ID=26426606

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8901207A Expired - Lifetime ES2016441A6 (es) 1988-04-07 1989-04-06 Un procedimiento para producir 1,1 -ciclobutanodicarboxilato (2-aminometilpirrolidin) platino ii, y sus derivados opticamente activos.

Country Status (4)

Country Link
KR (1) KR950000982B1 (es)
AT (1) AT392273B (es)
ES (1) ES2016441A6 (es)
HU (1) HU203558B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042364A1 (es) * 1991-06-05 1993-12-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas.
ES2056721A1 (es) * 1991-06-05 1994-10-01 Ferrer Int Mejoras en el objeto de la patente de invencion n{ 9101355 que se refiere a procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134103A (en) * 1983-01-21 1984-08-08 Tanabe Seiyaku Co Novel organic platinum complex and process for the preparation thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042364A1 (es) * 1991-06-05 1993-12-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas.
ES2056721A1 (es) * 1991-06-05 1994-10-01 Ferrer Int Mejoras en el objeto de la patente de invencion n{ 9101355 que se refiere a procedimiento de obtencion de nuevos derivados de platino con aminopirrolidinas.

Also Published As

Publication number Publication date
AT392273B (de) 1991-02-25
KR890016054A (ko) 1989-11-28
KR950000982B1 (ko) 1995-02-06
ATA81689A (de) 1990-08-15
HUT51639A (en) 1990-05-28
HU203558B (en) 1991-08-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040503