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ES2001031A6 - Un procedimiento para la preparacion de penicilinas que contienen un grupo oximino - Google Patents

Un procedimiento para la preparacion de penicilinas que contienen un grupo oximino

Info

Publication number
ES2001031A6
ES2001031A6 ES8600563A ES8600563A ES2001031A6 ES 2001031 A6 ES2001031 A6 ES 2001031A6 ES 8600563 A ES8600563 A ES 8600563A ES 8600563 A ES8600563 A ES 8600563A ES 2001031 A6 ES2001031 A6 ES 2001031A6
Authority
ES
Spain
Prior art keywords
beta
alpha
preparation
acid derivatives
penicillanic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8600563A
Other languages
English (en)
Inventor
Michael John Pearson
Richard Leonard Elliott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858518869A external-priority patent/GB8518869D0/en
Priority claimed from GB868610910A external-priority patent/GB8610910D0/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES2001031A6 publication Critical patent/ES2001031A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE DESCRIBE UN PROCEDIMIENTO PARA LA PREPARACION DE PENICILINAS QUE CONTIENEN UN GRUPO OXIMINO, DE FORMULA (I) O UNA SAL FARMACEUTICAMENTE ACEPTABLE O UN ESTER HIDROLIZABLE IN VIVO DEL MISMO: DONDE R1 ES HIDROGENO O UN GRUPO PROTECTOR DEL AMINO Y R ES METILO SUSTITUIDO; ALQUILO, ALQUENILO O ALQUIILO C2-12 OPCIONALMENTE SUSTITUIDO; CARBOCICLILO; ARILO O HETEROCICLILO, QUE COMPRENDE LA ACILACION DE UN COMPUESTO DE FORMULA (IV) O UNA SAL DEL MISMO. DONDE EL GRUPO AMINO ESTA OPCIONALMENTE SUSTITUIDO CON UN GRUPO QUE PERMITE QUE TENGA LUGAR LA ACILACION CON UN AGENTE ACILANTE DERIVADO DE UN ACIDO DE FORMULA (V) CUYAS DEFINICIONES DE Y, R Y R3 SE ENCUENTRAN EN LA DESCRIPCION. LOS COMPUESTOS ASI OBTENIDOS POSEEN PROPIEDADES ANTIBACTERIANAS Y SON UTILES EN EL TRATAMIENTO DE INFECCIONES BACTERIANAS EN EL HOMBRE Y EN LOS ANIMALES, CAUSADAS POR UNA GRAN VARIEDAD DE ORGANISMOS.
ES8600563A 1985-07-25 1986-07-24 Un procedimiento para la preparacion de penicilinas que contienen un grupo oximino Expired ES2001031A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858518869A GB8518869D0 (en) 1985-07-25 1985-07-25 Compounds
GB868610910A GB8610910D0 (en) 1986-05-03 1986-05-03 Compounds

Publications (1)

Publication Number Publication Date
ES2001031A6 true ES2001031A6 (es) 1988-04-16

Family

ID=26289559

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8600563A Expired ES2001031A6 (es) 1985-07-25 1986-07-24 Un procedimiento para la preparacion de penicilinas que contienen un grupo oximino

Country Status (9)

Country Link
US (1) US4816452A (es)
EP (1) EP0210815A3 (es)
AU (1) AU598199B2 (es)
CA (1) CA1283097C (es)
DK (1) DK353286A (es)
ES (1) ES2001031A6 (es)
GR (1) GR861966B (es)
NZ (1) NZ216946A (es)
PT (1) PT83048B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0867676A (ja) * 1994-03-30 1996-03-12 Eisai Kagaku Kk 保護アミノチアゾリル酢酸誘導体
HUP9601096A2 (hu) * 1996-04-26 1998-01-28 János Aradi Anti-HIV-aktivitással rendelkező gyógynövényalapú gyógyászati és gyógyhatású készítmény,és vegyületek
IT1295935B1 (it) 1997-10-30 1999-05-28 Acs Dobfar Spa Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
US20050245498A1 (en) * 2002-05-14 2005-11-03 Shoichet Brian K Sterically-awkward beta-lactamase inhibitors
ES2422603T3 (es) * 2007-05-31 2013-09-12 Shionogi & Co Compuestos oxiimino y el uso de estos
KR102254394B1 (ko) * 2020-07-16 2021-05-24 솔브레인 주식회사 박막 형성용 성장 억제제, 이를 이용한 박막 형성 방법 및 이로부터 제조된 반도체 기판

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399087A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Penicillin compounds
US3936443A (en) * 1974-05-03 1976-02-03 Glaxo Laboratories Limited Penicillin antibiotics
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
US4376203A (en) * 1976-01-23 1983-03-08 Roussell Uclaf Novel 3-acetoxymethyl-7-(iminoacetamido)-cephalosporanic acid derivatives
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
DE2923339A1 (de) * 1979-06-08 1980-12-18 Bayer Ag Penicillin-1,1-dioxide, ihre herstellung und ihre verwendung als arzneimittel
US4443444A (en) * 1980-08-11 1984-04-17 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4507487A (en) * 1982-09-23 1985-03-26 Bristol-Myers Company Chemical compounds
AU586215B2 (en) * 1985-01-21 1989-07-06 Nippon Pharmaceutical Development Institute Company Limited Novel ```-lactam antibiotics

Also Published As

Publication number Publication date
EP0210815A3 (en) 1988-04-20
DK353286D0 (da) 1986-07-24
AU6046686A (en) 1987-01-29
US4816452A (en) 1989-03-28
NZ216946A (en) 1990-03-27
EP0210815A2 (en) 1987-02-04
GR861966B (en) 1986-11-26
DK353286A (da) 1987-01-26
PT83048A (en) 1986-08-01
AU598199B2 (en) 1990-06-21
PT83048B (pt) 1988-10-14
CA1283097C (en) 1991-04-16

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-07-24