ES2097688A1 - HEXAHIDROAZEPINONAS AND TETRAHIDROBENZAZEPINONAS SUBSTITUTED. - Google Patents
HEXAHIDROAZEPINONAS AND TETRAHIDROBENZAZEPINONAS SUBSTITUTED.Info
- Publication number
- ES2097688A1 ES2097688A1 ES09301579A ES9301579A ES2097688A1 ES 2097688 A1 ES2097688 A1 ES 2097688A1 ES 09301579 A ES09301579 A ES 09301579A ES 9301579 A ES9301579 A ES 9301579A ES 2097688 A1 ES2097688 A1 ES 2097688A1
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- tetrahidrobenzazepinonas
- hexahidroazepinonas
- tetrahydrobenzazepinones
- hexahydroazepinones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- HRVRAYIYXRVAPR-UHFFFAOYSA-N 1,3,4,5-tetrahydro-1-benzazepin-2-one Chemical class N1C(=O)CCCC2=CC=CC=C21 HRVRAYIYXRVAPR-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- JBKVHLHDHHXQEQ-UHFFFAOYSA-N epsilon-caprolactam Chemical class O=C1CCCCCN1 JBKVHLHDHHXQEQ-UHFFFAOYSA-N 0.000 abstract 2
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Substituted hexahydroazepinones and tetrahydrobenzazepinones This invention relates to new substituted hexahydroazepinones and tetrahydrobenzazepinones of formula I and II where R1, Z1, Z2, Y1 and Y2 are as defined in the description and new intermediates used in the synthesis of these compounds. These compounds are useful in the treatment and prevention of gastrointestinal problems, pain and anxiety disturbances. <IMAGE>
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09301579A ES2097688A1 (en) | 1993-07-14 | 1993-07-14 | HEXAHIDROAZEPINONAS AND TETRAHIDROBENZAZEPINONAS SUBSTITUTED. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09301579A ES2097688A1 (en) | 1993-07-14 | 1993-07-14 | HEXAHIDROAZEPINONAS AND TETRAHIDROBENZAZEPINONAS SUBSTITUTED. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2097688A1 true ES2097688A1 (en) | 1997-04-01 |
Family
ID=8282549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09301579A Withdrawn ES2097688A1 (en) | 1993-07-14 | 1993-07-14 | HEXAHIDROAZEPINONAS AND TETRAHIDROBENZAZEPINONAS SUBSTITUTED. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2097688A1 (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767756A (en) * | 1987-07-17 | 1988-08-30 | E. R. Squibb & Sons, Inc. | 3-substituted benzazepines |
| EP0322779A2 (en) * | 1987-12-29 | 1989-07-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzolactam compounds and pharmaceutical uses thereof |
| EP0487207A1 (en) * | 1990-10-22 | 1992-05-27 | Merck & Co. Inc. | Benzolactam analogs as antagonists of CCK |
| WO1993015059A1 (en) * | 1992-01-27 | 1993-08-05 | Pfizer Inc. | 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists |
-
1993
- 1993-07-14 ES ES09301579A patent/ES2097688A1/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767756A (en) * | 1987-07-17 | 1988-08-30 | E. R. Squibb & Sons, Inc. | 3-substituted benzazepines |
| EP0322779A2 (en) * | 1987-12-29 | 1989-07-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzolactam compounds and pharmaceutical uses thereof |
| EP0487207A1 (en) * | 1990-10-22 | 1992-05-27 | Merck & Co. Inc. | Benzolactam analogs as antagonists of CCK |
| WO1993015059A1 (en) * | 1992-01-27 | 1993-08-05 | Pfizer Inc. | 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19970401 Kind code of ref document: A1 Effective date: 19970401 |
|
| FA2A | Application withdrawn |
Effective date: 19970611 |