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ES2092971T3 - Procedimiento para la purificacion de acido hialuronico y fraccion de acido hialuronico puro para utilizacion oftalmologica. - Google Patents

Procedimiento para la purificacion de acido hialuronico y fraccion de acido hialuronico puro para utilizacion oftalmologica.

Info

Publication number
ES2092971T3
ES2092971T3 ES92908628T ES92908628T ES2092971T3 ES 2092971 T3 ES2092971 T3 ES 2092971T3 ES 92908628 T ES92908628 T ES 92908628T ES 92908628 T ES92908628 T ES 92908628T ES 2092971 T3 ES2092971 T3 ES 2092971T3
Authority
ES
Spain
Prior art keywords
hyaluronic acid
fraction
purification
procedure
pure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92908628T
Other languages
English (en)
Other versions
ES2092971T1 (es
Inventor
Aurelio Romeo
Silvana Lorenzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11389548&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2092971(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of ES2092971T1 publication Critical patent/ES2092971T1/es
Application granted granted Critical
Publication of ES2092971T3 publication Critical patent/ES2092971T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

SE PRESENTA UNA FRACCION ALTAMENTE PURA DE ACIDO HIALURONICO QUE TIENE ACCION ANTIINFLAMATORIA Y EVITA LAS COMPLICACIONES POSTOPERATORIAS EN LA CIRUGIA OCULAR. TAMBIEN SE PRESENTA UN PROCESO PARA LA PREPARACION DE ACIDO HIALURONICO EN UNA SAL DE AMONIO CUATERNARIO CORRESPONDIENTE, SIGUIENDO PROCEDIMIENTOS DE PURIFICACION, RECONVIRTIENDO LA SAL DE AMONIO CUATERNARIO EN SAL DE SODIO DE ACIDO HIALURONICO.
ES92908628T 1991-04-19 1992-04-16 Procedimiento para la purificacion de acido hialuronico y fraccion de acido hialuronico puro para utilizacion oftalmologica. Expired - Lifetime ES2092971T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD910077A IT1247175B (it) 1991-04-19 1991-04-19 Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico.

Publications (2)

Publication Number Publication Date
ES2092971T1 ES2092971T1 (es) 1996-12-16
ES2092971T3 true ES2092971T3 (es) 2000-01-01

Family

ID=11389548

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92908628T Expired - Lifetime ES2092971T3 (es) 1991-04-19 1992-04-16 Procedimiento para la purificacion de acido hialuronico y fraccion de acido hialuronico puro para utilizacion oftalmologica.

Country Status (24)

Country Link
US (1) US5559104A (es)
EP (1) EP0535200B1 (es)
JP (1) JP2580458B2 (es)
KR (1) KR0178544B1 (es)
AT (1) ATE186307T1 (es)
AU (1) AU653022B2 (es)
BR (1) BR9205240A (es)
CA (1) CA2084875C (es)
CZ (1) CZ282248B6 (es)
DE (1) DE69230242T2 (es)
DK (1) DK0535200T3 (es)
ES (1) ES2092971T3 (es)
FI (1) FI104973B (es)
GR (1) GR3032434T3 (es)
HU (1) HU215193B (es)
IL (2) IL101611A (es)
IT (1) IT1247175B (es)
NO (1) NO305520B1 (es)
PL (1) PL168477B1 (es)
RU (1) RU2128666C1 (es)
SG (1) SG46515A1 (es)
SK (1) SK280191B6 (es)
UA (1) UA27229C2 (es)
WO (1) WO1992018543A1 (es)

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IT1274984B (it) * 1994-12-09 1997-07-29 Technopharma Sa Soluzioni viscosizzate con ialuronato di sodio per l'uso come fluido maschera nella fotocheratectomia terapeutica mediante laser a accimeri
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IT1287967B1 (it) 1996-10-17 1998-09-10 Fidia Spa In Amministrazione S Preparazioni farmaceutiche per uso anestetico locale
IT1291452B1 (it) 1997-04-14 1999-01-11 Fidia Advanced Biopolymers Srl Rivestimento a base di acido ialuronico e suoi derivati per la protezione di parti elettroniche da agenti esterni
US6919076B1 (en) 1998-01-20 2005-07-19 Pericor Science, Inc. Conjugates of agents and transglutaminase substrate linking molecules
US6958148B1 (en) 1998-01-20 2005-10-25 Pericor Science, Inc. Linkage of agents to body tissue using microparticles and transglutaminase
IL139354A (en) 1998-05-29 2005-08-31 Bone Care Internat Inc Method for making hydroxy-25 ene-vitamin d compounds
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RU2147876C1 (ru) * 1999-07-08 2000-04-27 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Фармацевтическая композиция для обезболивания в офтальмологии
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KR20140024863A (ko) * 2011-03-02 2014-03-03 덴키 가가쿠 고교 가부시기가이샤 히알루론산 또는 히알루론산염을 포함하는 수용액
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RU2477138C1 (ru) * 2011-11-02 2013-03-10 Общество с ограниченной ответственностью Научно-производственное предприятие "Тульская индустрия ЛТД" Способ получения заполняющего материала для пластической хирургии и инструментальной косметологии, заполняющий материал и способ введения заполняющего материала в проблемную зону
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CN111228653A (zh) 2018-11-13 2020-06-05 格莱科米拉治疗公司 用电离辐射加强癌症治疗的方法
IT201900019724A1 (it) * 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”
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Also Published As

Publication number Publication date
ITPD910077A0 (it) 1991-04-19
PL297297A1 (en) 1993-09-06
CZ282248B6 (cs) 1997-06-11
CA2084875A1 (en) 1992-10-20
FI925756A0 (fi) 1992-12-18
EP0535200B1 (en) 1999-11-03
KR0178544B1 (ko) 1999-04-01
IT1247175B (it) 1994-12-12
UA27229C2 (uk) 2000-08-15
EP0535200A1 (en) 1993-04-07
HU9204012D0 (en) 1993-03-29
ITPD910077A1 (it) 1992-10-19
WO1992018543A1 (en) 1992-10-29
IL113453A0 (en) 1995-07-31
US5559104A (en) 1996-09-24
JPH05508183A (ja) 1993-11-18
ES2092971T1 (es) 1996-12-16
IL101611A (en) 1996-06-18
RU2128666C1 (ru) 1999-04-10
KR930700557A (ko) 1993-03-15
ATE186307T1 (de) 1999-11-15
PL168477B1 (pl) 1996-02-29
JP2580458B2 (ja) 1997-02-12
DE69230242D1 (de) 1999-12-09
NO924873L (no) 1993-02-19
NO924873D0 (no) 1992-12-16
NO305520B1 (no) 1999-06-14
DK0535200T3 (da) 2000-05-08
HUT63186A (en) 1993-07-28
SK377192A3 (en) 1995-06-07
SG46515A1 (en) 1998-02-20
IL113453A (en) 1995-07-31
HU215193B (hu) 1998-10-28
AU1576692A (en) 1992-11-17
FI104973B (fi) 2000-05-15
SK280191B6 (sk) 1999-09-10
BR9205240A (pt) 1993-08-31
CZ377192A3 (en) 1993-05-12
DE69230242T2 (de) 2000-06-21
AU653022B2 (en) 1994-09-15
GR3032434T3 (en) 2000-05-31
FI925756L (fi) 1992-12-18
CA2084875C (en) 1998-01-06

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