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ES2092714T3 - Derivados de indol. - Google Patents

Derivados de indol.

Info

Publication number
ES2092714T3
ES2092714T3 ES93105695T ES93105695T ES2092714T3 ES 2092714 T3 ES2092714 T3 ES 2092714T3 ES 93105695 T ES93105695 T ES 93105695T ES 93105695 T ES93105695 T ES 93105695T ES 2092714 T3 ES2092714 T3 ES 2092714T3
Authority
ES
Spain
Prior art keywords
group
indol
derivatives
alkyl
formile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93105695T
Other languages
English (en)
Inventor
Masaji Kasai
Hitoshi Arai
Hiroshi Nishikawa
Takehiro Ogasa
Masahiko Kinugawa
Shinji Tomioka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of ES2092714T3 publication Critical patent/ES2092714T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

UN DERIVADO DE INDOL REPRESENTADO POR LA FORMULA (I): DONDE R1 ES UN GRUPO ALKOXIMETILO INFERIOR O UN GRUPO FORMILO, R2 ES UN GRUPO ALKILO INFERIOR, R3 ES UN ATOMO DE HIDROGENO O UN GRUPO ALKILO INFERIOR Y R4 ES UN ATOMO DE HIDROGENO O UN GRUPO ALKILO INFERIOR, QUE ES UTIL COMO UN INTERMEDIARIO PARA LA SINTESIS DE UN COMPUESTO, 5 ETILQUE TIENE UNA ACTIVIDAD ANITUMORAL.
ES93105695T 1992-04-07 1993-04-06 Derivados de indol. Expired - Lifetime ES2092714T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8527692 1992-04-07

Publications (1)

Publication Number Publication Date
ES2092714T3 true ES2092714T3 (es) 1996-12-01

Family

ID=13854045

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93105695T Expired - Lifetime ES2092714T3 (es) 1992-04-07 1993-04-06 Derivados de indol.

Country Status (9)

Country Link
US (1) US5344938A (es)
EP (1) EP0565059B1 (es)
JP (1) JPH0616628A (es)
AT (1) ATE140919T1 (es)
CA (1) CA2093304A1 (es)
DE (1) DE69303847T2 (es)
DK (1) DK0565059T3 (es)
ES (1) ES2092714T3 (es)
GR (1) GR3021427T3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5669657A (en) * 1994-12-13 1997-09-23 Hori Glass Co., Ltd. Sunroof assembly for motor vehicle
CN1326521C (zh) * 2002-09-13 2007-07-18 成都地奥制药集团有限公司 3－吲哚醛及其衍生物具有抑制体外肿瘤细胞的作用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302874B1 (en) * 1986-04-17 1992-12-02 SPECKAMP, Willem Nico Indoloquinone compounds

Also Published As

Publication number Publication date
DE69303847D1 (de) 1996-09-05
JPH0616628A (ja) 1994-01-25
ATE140919T1 (de) 1996-08-15
US5344938A (en) 1994-09-06
DK0565059T3 (da) 1996-10-14
DE69303847T2 (de) 1997-03-13
EP0565059A1 (en) 1993-10-13
CA2093304A1 (en) 1993-10-08
GR3021427T3 (en) 1997-01-31
EP0565059B1 (en) 1996-07-31

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