ES2070778A1 - Composicion de liposomas y su procedimiento de obtencion. - Google Patents
Composicion de liposomas y su procedimiento de obtencion.Info
- Publication number
- ES2070778A1 ES2070778A1 ES09302111A ES9302111A ES2070778A1 ES 2070778 A1 ES2070778 A1 ES 2070778A1 ES 09302111 A ES09302111 A ES 09302111A ES 9302111 A ES9302111 A ES 9302111A ES 2070778 A1 ES2070778 A1 ES 2070778A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- liposomes
- obtaining
- liposome composition
- aqueous phase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002502 liposome Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 239000002537 cosmetic Substances 0.000 abstract 2
- 239000003995 emulsifying agent Substances 0.000 abstract 2
- 239000000839 emulsion Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 235000003441 saturated fatty acids Nutrition 0.000 abstract 1
- 150000004671 saturated fatty acids Chemical class 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
COMPOSICION DE LIPOSOMAS Y SU PROCEDIMIENTO DE OBTENCION. COMPOSICIONES COSMETICAS Y FARMACEUTICAS DE FASE EXTERNA ACUOSA CONTENIENDO LIPOSOMAS FOSFOLIPIDICOS CARGADOS O NO, OTROS PRINCIPIOS ACTIVOS Y EMULSIONANTES NO IONICOS DEL TIPO DE ESTERES DE GLICERINA Y DE POLIETILENGLICOL DE ACIDOS GRASOS SATURADOS, EN UNA RELACION EMULSIONANTES/FOSFOLIPIDOS 80-150/1 EN PESO, Y UN PROCEDIMIENTO QUE PERMITE DISPERSAR LOS LIPOSOMAS, SIN QUE ESTOS SEAN SOLUBILIZADOS, PERMANECIENDO ESTABLES DURANTE EL PROCESO Y EN LA EMULSION OBTENIDA, EL CUAL SE CARACTERIZA POR PREPARAR INICIALMENTE LA EMULSION DE FASE EXTERNA ACUOSA, ADICIONAR SOBRE ESTA LOS PRINCIPIOS ACTIVOS COSMETICOS Y LOS ADITIVOS A UNA TEMPERATURA ENTRE 30 Y 65GC Y, FINALMENTE, INCORPORAR LA SUSPENSION DE LIPOSOMAS A UNA TEMPERATURA ENTRE 20 Y 40GC Y A UNA VELOCIDAD DE AGITACION MENOR DE 50 R.P.M.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9302111A ES2070778B1 (es) | 1993-10-07 | 1993-10-07 | Composicion de liposomas y su procedimiento de obtencion. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9302111A ES2070778B1 (es) | 1993-10-07 | 1993-10-07 | Composicion de liposomas y su procedimiento de obtencion. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2070778A1 true ES2070778A1 (es) | 1995-06-01 |
| ES2070778B1 ES2070778B1 (es) | 1995-12-16 |
Family
ID=8283253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9302111A Expired - Fee Related ES2070778B1 (es) | 1993-10-07 | 1993-10-07 | Composicion de liposomas y su procedimiento de obtencion. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2070778B1 (es) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES478056A1 (es) * | 1978-02-24 | 1980-04-16 | Papahadjopoulos Demetrios | Procedimiento de fabricacion de capsulas lipidicas que con- tienen uno o varios materiales biologicamente activos. |
| EP0270460A2 (fr) * | 1986-12-05 | 1988-06-08 | The Liposome Company, Inc. | Microcristaux comportant une substance active présentant une affinité pour les phospholipides et au moins un phospholipide, procédé de préparation |
| FR2608942A1 (fr) * | 1986-12-31 | 1988-07-01 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules |
| US5093198A (en) * | 1987-06-19 | 1992-03-03 | Temple University | Adjuvant-enhanced sustained release composition and method for making |
-
1993
- 1993-10-07 ES ES9302111A patent/ES2070778B1/es not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES478056A1 (es) * | 1978-02-24 | 1980-04-16 | Papahadjopoulos Demetrios | Procedimiento de fabricacion de capsulas lipidicas que con- tienen uno o varios materiales biologicamente activos. |
| EP0270460A2 (fr) * | 1986-12-05 | 1988-06-08 | The Liposome Company, Inc. | Microcristaux comportant une substance active présentant une affinité pour les phospholipides et au moins un phospholipide, procédé de préparation |
| FR2608942A1 (fr) * | 1986-12-31 | 1988-07-01 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules |
| US5093198A (en) * | 1987-06-19 | 1992-03-03 | Temple University | Adjuvant-enhanced sustained release composition and method for making |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2070778B1 (es) | 1995-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20141120 |