ES2070087A1 - Indole derivatives - Google Patents
Indole derivativesInfo
- Publication number
- ES2070087A1 ES2070087A1 ES09301804A ES9301804A ES2070087A1 ES 2070087 A1 ES2070087 A1 ES 2070087A1 ES 09301804 A ES09301804 A ES 09301804A ES 9301804 A ES9301804 A ES 9301804A ES 2070087 A1 ES2070087 A1 ES 2070087A1
- Authority
- ES
- Spain
- Prior art keywords
- indole derivatives
- compounds
- useful
- vasodilators
- migraine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000002220 antihypertensive agent Substances 0.000 abstract 1
- 229940030600 antihypertensive agent Drugs 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of formula I, where W, n, m, R1 and R11 are defined in detail in the report. These compounds are potential serotonin (5-HT1) agonists and are useful for the treatment of migraine and other disorders, also being useful as centrally acting antihypertensives and vasodilators.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9301804A ES2070087B1 (en) | 1993-08-13 | 1993-08-13 | DERIVATIVES OF INDOL |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9301804A ES2070087B1 (en) | 1993-08-13 | 1993-08-13 | DERIVATIVES OF INDOL |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2070087A1 true ES2070087A1 (en) | 1995-05-16 |
| ES2070087B1 ES2070087B1 (en) | 1996-02-16 |
Family
ID=8282858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9301804A Expired - Lifetime ES2070087B1 (en) | 1993-08-13 | 1993-08-13 | DERIVATIVES OF INDOL |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2070087B1 (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0313397A1 (en) * | 1987-10-23 | 1989-04-26 | The Wellcome Foundation Limited | Therapeutic heterocyclic compounds |
| EP0438230A2 (en) * | 1990-01-17 | 1991-07-24 | MERCK SHARP & DOHME LTD. | Indole-substituted five-membered heteroaromatic compounds |
| WO1991018897A1 (en) * | 1990-06-07 | 1991-12-12 | The Wellcome Foundation Limited | Therapeutic heterocyclic compounds |
| WO1992006976A1 (en) * | 1990-10-18 | 1992-04-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivative |
| WO1992013856A1 (en) * | 1991-02-12 | 1992-08-20 | Pfizer Inc. | 5-heteroyl indole derivatives |
| WO1993020073A1 (en) * | 1992-04-07 | 1993-10-14 | Pfizer Inc. | Indole derivatives as 5-ht1 agonists |
-
1993
- 1993-08-13 ES ES9301804A patent/ES2070087B1/en not_active Expired - Lifetime
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0313397A1 (en) * | 1987-10-23 | 1989-04-26 | The Wellcome Foundation Limited | Therapeutic heterocyclic compounds |
| EP0438230A2 (en) * | 1990-01-17 | 1991-07-24 | MERCK SHARP & DOHME LTD. | Indole-substituted five-membered heteroaromatic compounds |
| WO1991018897A1 (en) * | 1990-06-07 | 1991-12-12 | The Wellcome Foundation Limited | Therapeutic heterocyclic compounds |
| WO1992006976A1 (en) * | 1990-10-18 | 1992-04-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivative |
| WO1992013856A1 (en) * | 1991-02-12 | 1992-08-20 | Pfizer Inc. | 5-heteroyl indole derivatives |
| WO1993020073A1 (en) * | 1992-04-07 | 1993-10-14 | Pfizer Inc. | Indole derivatives as 5-ht1 agonists |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2070087B1 (en) | 1996-02-16 |
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