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ES2055659A1 - Procedimiento para la preparacion de compuestos farmaceuticos que reducen selectivamente el nivel de lipidos de la sangre - Google Patents

Procedimiento para la preparacion de compuestos farmaceuticos que reducen selectivamente el nivel de lipidos de la sangre

Info

Publication number
ES2055659A1
ES2055659A1 ES09202518A ES9202518A ES2055659A1 ES 2055659 A1 ES2055659 A1 ES 2055659A1 ES 09202518 A ES09202518 A ES 09202518A ES 9202518 A ES9202518 A ES 9202518A ES 2055659 A1 ES2055659 A1 ES 2055659A1
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
preparation
blood
lipid level
composition selectively
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09202518A
Other languages
English (en)
Other versions
ES2055659B1 (es
Inventor
Mate Dr Hidvegi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES2055659A1 publication Critical patent/ES2055659A1/es
Application granted granted Critical
Publication of ES2055659B1 publication Critical patent/ES2055659B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS FARMACEUTICOS QUE REDUCEN SELECTIVAMENTE EL NIVEL DE LIPIDOS DE LA SANGRE. LA INVENCION SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION DE UN COMPUESTO FARMACEUTICO QUE REBAJA DE FORMA SELECTIVA EL NIVEL DE LIPIDOS EN LA SANGRE, EN BASE A UN EXTRACTO DE LA SEMILLA, DE LA RAIZ, DEL TALLO Y/O DE LA HOJA DE ALFALFA. DE ACUERDO CON EL PROCEDIMIENTO LA INVENCION, LA EXTRACCION SE REALIZA CON AGUA O UNA SOLUCION ACUOSA A UNA TEMPERATURA MINIMA DE 40GC Y UN PH MAXIMO DE 8, SEGUN EL CUAL EL EXTRACTO OBTENIDO ES TRANSFORMADO SOLO O JUNTO CON POLISACARIDOS PRACTICA O COMPLETAMENTE INDIGERIBLES Y, OPCIONALMENTE, CON PORTADORES DE USO NORMAL EN LA INDUSTRIA FARMACEUTICA, PARA OBTENER UN COMPUESTO FARMACEUTICO. EL COMPUESTO DE ACUERDO CON ESTA INVENCION NO CONTIENE NI CANAVANINAS (QUE ES UN AMINOACIDO TOXICO) NI CUMESTROL (CON EFECTO HORMONAL).
ES09202518A 1991-12-12 1992-12-11 Procedimiento para la preparacion de compuestos farmaceuticos que reducen selectivamente el nivel de lipidos en la sangre Expired - Lifetime ES2055659B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU913928A HU208256B (en) 1991-12-12 1991-12-12 Process for producing pharmaceutical compositions suitable for the selective reduction of lipoid level of blood

Publications (2)

Publication Number Publication Date
ES2055659A1 true ES2055659A1 (es) 1994-08-16
ES2055659B1 ES2055659B1 (es) 1995-03-01

Family

ID=10966105

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09202518A Expired - Lifetime ES2055659B1 (es) 1991-12-12 1992-12-11 Procedimiento para la preparacion de compuestos farmaceuticos que reducen selectivamente el nivel de lipidos en la sangre

Country Status (25)

Country Link
US (1) US5277910A (es)
JP (1) JPH05286865A (es)
KR (1) KR930012033A (es)
CN (1) CN1074123A (es)
AT (1) ATA243992A (es)
AU (1) AU657822B2 (es)
BE (1) BE1006341A3 (es)
CA (1) CA2085215A1 (es)
CZ (1) CZ363492A3 (es)
DE (1) DE4242149A1 (es)
DK (1) DK148092A (es)
ES (1) ES2055659B1 (es)
FI (1) FI925633L (es)
FR (1) FR2684877B1 (es)
GB (1) GB2262230B (es)
GR (1) GR920100548A (es)
HU (1) HU208256B (es)
IL (1) IL104067A0 (es)
IT (1) IT1256652B (es)
LU (1) LU88200A1 (es)
MX (1) MX9207222A (es)
NL (1) NL9202144A (es)
PL (1) PL296972A1 (es)
SE (1) SE9203744L (es)
ZA (1) ZA929622B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU208256B (en) * 1991-12-12 1993-09-28 Mate Hidvegi Process for producing pharmaceutical compositions suitable for the selective reduction of lipoid level of blood
WO1995000158A1 (en) * 1993-06-25 1995-01-05 Bio-Sphere Technology Dietary supplement incorporating beta-sitosterol and pectin
US5674496A (en) * 1993-10-20 1997-10-07 New Mexico Tech Research Foundation Animal repellent
US6814962B1 (en) * 1994-06-02 2004-11-09 Aventis Pharma S.A. Recombinant viruses and their use for treatment of atherosclerosis and other forms of coronary artery disease and method, reagent, and kit for evaluating susceptibility to same
US5516528A (en) * 1995-01-13 1996-05-14 Wake Forest University Dietary phytoestrogen in estrogen replacement therapy
US6193766B1 (en) * 1996-06-27 2001-02-27 Barto/Jordan Company, Inc. Alfalfa extract fuel additive for reducing pollutant emissions
US6086882A (en) * 1997-08-06 2000-07-11 National Institute For Pharmaceutical Research Phytodrug for management of peptic ulcer and methods of preparing and using same
US5786343A (en) * 1997-03-05 1998-07-28 Immudyne, Inc. Phagocytosis activator compositions and their use
GB2327607B8 (en) * 1997-07-31 2005-03-30 Litton Internat Company Ltd A process for producing a herbal extract composition
DE19750453A1 (de) * 1997-11-14 1999-05-27 Henkel Kgaa Verwendung von Wirkstoffmischungen zur Herstellung von hypocholesterinämischen Mitteln
US6232351B1 (en) 1998-05-22 2001-05-15 Amway Corporation Co-processed botanical plant composition
US6150399A (en) * 1998-06-30 2000-11-21 Abbott Laboratories Soy-based nutritional products
DE19857816C2 (de) 1998-12-15 2001-02-01 Bionorica Arzneimittel Gmbh Fließfähige, pressfertige Arzneimittelvorprodukte für Tabletten, Pellets und Dragees, sowie Verfahren zu deren Herstellung
FR2794616B1 (fr) * 1999-06-11 2001-09-07 Tekory S A R L Supplement alimentaire naturel destine a diminuer le taux de cholesterol plasmatique et procede pour le preparer
US6503543B1 (en) 2000-05-26 2003-01-07 Craig J. Hudson Tryptophan source from plants and uses therefor
US6866874B2 (en) 2000-05-26 2005-03-15 Susan P. Hudson Tryptophan source from plants and uses therefor
US20020119928A1 (en) * 2000-10-27 2002-08-29 Mcanalley Bill H. Dietary supplement compositions
US7815946B1 (en) * 2001-04-05 2010-10-19 Diakron Pharmaceuticals, Inc. Anti-diabetic and cholesterol lowering preparation from fenugreek seeds
JP5110673B2 (ja) * 2001-07-10 2012-12-26 丸善製薬株式会社 リパーゼ阻害剤
FR2854769B1 (fr) * 2003-05-16 2009-07-17 Alfalis Utilisation d'un extrait soluble de luzerne pour freiner la prise de poids chez les mammiferes
WO2008006224A1 (en) 2006-07-13 2008-01-17 Medicago, Inc Medicagenic acid saponin and uses thereof
US20090226549A1 (en) 2008-03-06 2009-09-10 Kenneth John Hughes Herbal extracts and flavor systems for oral products and methods of making the same
WO2012004227A1 (en) * 2010-07-06 2012-01-12 Unilever Plc Malvidin for promoting hair growth
KR20200040583A (ko) 2018-10-10 2020-04-20 (주)아모레퍼시픽 코티존 환원효소 저해용 조성물
CN114853918B (zh) * 2022-04-26 2023-03-31 沈阳化工大学 一种具有抗氧化降脂活性的紫花苜蓿根部多糖制备方法
CN115490584B (zh) * 2022-09-28 2023-07-14 厦门中药厂有限公司 Megastigmane类化合物及其制备方法和应用

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449760A (en) * 1965-10-22 1969-06-10 Nat Res Dev Extraction of sapogenins from vegetable materials
FR2187328A1 (en) * 1972-06-13 1974-01-18 Froment Pier E De Non-saponified lucerne extract - useful in dermatology cosmetology and as aid to cicatrisation
GB1378278A (en) * 1972-03-31 1974-12-27 Pacific Chem Ind Co Total saponin extracts from panax ginseng c a meyer and process for the production thereof
US3901875A (en) * 1972-03-31 1975-08-26 Pacific Chem Ind Co Extraction of ginseng saponin
US4594412A (en) * 1983-03-23 1986-06-10 Osaka Chemical Laboratory Co., Ltd. Method of isolating soyasaponins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780183A (en) * 1971-01-25 1973-12-18 Edwards G Wheeler Plant protein product and process
SU624634A1 (ru) * 1975-09-25 1978-09-25 Харьковский Научно-Исследовательский Химико-Фармацевтический Институт Способ получени ингибитора,обладающего антифибринолитическим и противовоспалительным действием
JPS59166055A (ja) * 1983-03-11 1984-09-19 Osaka Chem Lab 牧草を原料とする食品
JPS646987A (en) * 1987-06-30 1989-01-11 Ricoh Kk Controlling method for toner concentration of developer for electrophotographic device
FR2669225B1 (fr) * 1990-11-21 1993-11-12 Lvmh Recherche Gie Utilisation de saponines de medicago pour la preparation de compositions cosmetiques ou pharmaceutiques, notamment dermatologiques.
HU208256B (en) * 1991-12-12 1993-09-28 Mate Hidvegi Process for producing pharmaceutical compositions suitable for the selective reduction of lipoid level of blood

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449760A (en) * 1965-10-22 1969-06-10 Nat Res Dev Extraction of sapogenins from vegetable materials
GB1378278A (en) * 1972-03-31 1974-12-27 Pacific Chem Ind Co Total saponin extracts from panax ginseng c a meyer and process for the production thereof
US3901875A (en) * 1972-03-31 1975-08-26 Pacific Chem Ind Co Extraction of ginseng saponin
FR2187328A1 (en) * 1972-06-13 1974-01-18 Froment Pier E De Non-saponified lucerne extract - useful in dermatology cosmetology and as aid to cicatrisation
US4594412A (en) * 1983-03-23 1986-06-10 Osaka Chemical Laboratory Co., Ltd. Method of isolating soyasaponins

Also Published As

Publication number Publication date
NL9202144A (nl) 1993-07-01
ZA929622B (en) 1995-09-26
GB2262230B (en) 1995-10-11
MX9207222A (es) 1993-06-01
BE1006341A3 (fr) 1994-07-26
FR2684877A1 (fr) 1993-06-18
US5277910A (en) 1994-01-11
ITMI922842A1 (it) 1994-06-11
FI925633A7 (fi) 1993-06-13
CN1074123A (zh) 1993-07-14
CA2085215A1 (en) 1993-06-13
SE9203744L (sv) 1993-06-13
GB2262230A (en) 1993-06-16
AU3005492A (en) 1993-06-17
IL104067A0 (en) 1993-05-13
DK148092A (da) 1993-06-13
DE4242149A1 (es) 1993-06-17
HU913928D0 (en) 1992-02-28
PL296972A1 (en) 1993-08-23
FI925633L (fi) 1993-06-13
FI925633A0 (fi) 1992-12-11
KR930012033A (ko) 1993-07-20
GR920100548A (el) 1993-08-31
FR2684877B1 (fr) 1994-12-30
HU208256B (en) 1993-09-28
ES2055659B1 (es) 1995-03-01
GB9225866D0 (en) 1993-02-03
CZ363492A3 (en) 1993-09-15
AU657822B2 (en) 1995-03-23
IT1256652B (it) 1995-12-12
JPH05286865A (ja) 1993-11-02
ATA243992A (de) 2000-02-15
SE9203744D0 (sv) 1992-12-11
LU88200A1 (fr) 1993-04-15
ITMI922842A0 (it) 1992-12-11
DK148092D0 (da) 1992-12-09

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Legal Events

Date Code Title Description
FA2A Application withdrawn

Effective date: 19950920