ES2043619T3 - Adhesivo para administracion percutanea. - Google Patents
Adhesivo para administracion percutanea.Info
- Publication number
- ES2043619T3 ES2043619T3 ES87106969T ES87106969T ES2043619T3 ES 2043619 T3 ES2043619 T3 ES 2043619T3 ES 87106969 T ES87106969 T ES 87106969T ES 87106969 T ES87106969 T ES 87106969T ES 2043619 T3 ES2043619 T3 ES 2043619T3
- Authority
- ES
- Spain
- Prior art keywords
- adhesive
- hydrophylic
- skin
- solid
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000853 adhesive Substances 0.000 title abstract 4
- 230000001070 adhesive effect Effects 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 230000015556 catabolic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000001766 physiological effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/58—Adhesives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/10—Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/71—Monoisocyanates or monoisothiocyanates
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
- C09J175/04—Polyurethanes
- C09J175/08—Polyurethanes from polyethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN ADHESIVO PARA ADMINISTRACION PERCUTANEA QUE TIENE UNA CAPA QUE CONTIENE MEDICAMENTO, COMPUESTA DE UN COMPONENTE BASE QUE COMPRENDE PRINCIPALMENTE UN POLIMERO ANFIFILICO SENSIBLE AL CALOR Y AL AGUA Y UN MEDICAMENTO INCORPORADO EN EL COMPONENTE BASE. EL COMPUESTO ANFIFILICO TIENE UNA ESTRUCTURA AFILADA HIDROFOBICA-HIDROFILICA CARACTERISTICA, Y SE PUEDEN DISOLVER O DISPERSAR EN EL DE MODO ESTABLE VARIOS MEDICAMENTOS DE AMPLIO CAMPO LIQUIDOS O SOLIDOS, LIPOFILICOS (HIDROFOBICOS) O HIDROFILICOS.EL MEDICAMENTO PERMANECE ESTABLE EN LA CAPA QUE LE CONTIENE, SIN QUE SE LIBERE O DIFUNDA MIENTRAS LOS ADHESIVOS ESTAN ALMACENADOS, Y POR APLICACION A LA PIEL EL MEDICAMENTO SE LIBERA GRADUALMENTE Y DIFUNDE EN LA PIEL CON GRAN APROVECHAMIENTO EN UNA MUESTRA CONTROLADA ESPECIFICAMENTE. EL ADHESIVO PRESENTE ES ESPECIALMENTE ADECUADO PARA PRESENTACION ENDERMICA DE UNA PEQUEÑA CANTIDAD DE UNA SUSTANCIA DE ACTIVIDAD FISIOLOGICA ELEVADA QUE ES INESTABLE Y SE DESCOMPONE FACILMENTE POR EL CALOR O EL AGUA.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10863386 | 1986-05-14 | ||
| JP8377287A JPH0725666B2 (ja) | 1986-05-14 | 1987-04-07 | 経皮投与用貼付剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2043619T3 true ES2043619T3 (es) | 1994-01-01 |
Family
ID=26424811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES87106969T Expired - Lifetime ES2043619T3 (es) | 1986-05-14 | 1987-05-14 | Adhesivo para administracion percutanea. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US4997656A (es) |
| EP (1) | EP0245858B1 (es) |
| DE (1) | DE3780700T2 (es) |
| ES (1) | ES2043619T3 (es) |
| GR (1) | GR3005989T3 (es) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2099273C (en) * | 1991-11-02 | 2000-03-28 | Yasuo Shikinami | Pressure sensitive adhesives for transdermal absorption formulations |
| US5384333A (en) * | 1992-03-17 | 1995-01-24 | University Of Miami | Biodegradable injectable drug delivery polymer |
| JP3382638B2 (ja) * | 1992-07-17 | 2003-03-04 | コニシ株式会社 | 粘着テープ |
| US5681579A (en) * | 1993-03-22 | 1997-10-28 | E.R. Squibb & Sons, Inc. | Polymeric support wound dressing |
| US5773490A (en) * | 1993-06-24 | 1998-06-30 | Takiron Co., Ltd. | Pressure sensitive adhesive for transdermal absorption formulations |
| JP3168367B2 (ja) * | 1993-07-30 | 2001-05-21 | タキロン株式会社 | 相分離した膜 |
| US5723145A (en) * | 1993-09-30 | 1998-03-03 | Takiron Co., Ltd. | Transdermal absorption preparation |
| CN1115964A (zh) * | 1993-09-30 | 1996-01-31 | 多喜兰株式会社 | 经皮吸收制剂 |
| US6298558B1 (en) * | 1994-10-31 | 2001-10-09 | The Gillette Company | Skin engaging member |
| US5676972A (en) * | 1995-02-16 | 1997-10-14 | The University Of Akron | Time-release delivery matrix composition and corresponding controlled-release compositions |
| US5730721A (en) * | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
| KR100622332B1 (ko) * | 1999-04-01 | 2006-09-13 | 알자 코포레이션 | 폴리우레탄 약물 리저버를 함유하는 경피 약물 수송 장치 |
| FR2792545B1 (fr) * | 1999-04-20 | 2001-06-01 | Oreal | Composition foisonnee, son procede de fabrication et son utilisation notamment comme composition cosmetique |
| US7470738B2 (en) * | 2001-12-27 | 2008-12-30 | Sanyo Chemical Industries, Ltd. | Non-aqueous absorbent and use thereof |
| US20040137039A1 (en) * | 2002-07-22 | 2004-07-15 | Trustees Of Stevens Institute Of Technology | Methods for controlled release of molecules from layered polymer films |
| US20050008828A1 (en) * | 2002-07-25 | 2005-01-13 | Trustees Of Stevens Institute Of Technology | Patterned polymer microgel and method of forming same |
| EP1567559A4 (en) * | 2002-11-12 | 2008-04-16 | Polymer Technology Group Inc | REGULATION OF MOLECULAR POLYMER SURFACE ARCHITECTURE USING AMPHIPATHIC TERMINAL GROUPS |
| US20060014003A1 (en) * | 2003-07-24 | 2006-01-19 | Libera Matthew R | Functional nano-scale gels |
| CA2541974A1 (en) * | 2003-10-02 | 2005-04-14 | Trustees Of Stevens Institute Of Technology | Capsules of multilayered neutral polymer films associated by hydrogen bonding |
| US20070009582A1 (en) * | 2003-10-07 | 2007-01-11 | Madsen Niels J | Composition useful as an adhesive and use of such a composition |
| EP1962867B1 (en) * | 2005-12-06 | 2013-06-19 | Covidien LP | Biocompatible surgical compositions |
| WO2007067624A2 (en) | 2005-12-06 | 2007-06-14 | Tyco Healthcare Group Lp | Bioabsorbable compounds and compositions containing them |
| JP2009518129A (ja) | 2005-12-06 | 2009-05-07 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 生体吸収性外科用組成物 |
| JP5088894B2 (ja) * | 2005-12-06 | 2012-12-05 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 生体適合性組織封止剤および接着剤 |
| JP2009518519A (ja) * | 2005-12-06 | 2009-05-07 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 官能化ポリエチレングリコールのカルボジイミド架橋 |
| US20070135566A1 (en) * | 2005-12-08 | 2007-06-14 | Tyco Healthcare Group Lp | Viscosity-reduced sprayable compositions |
| CA2630327C (en) | 2005-12-08 | 2015-05-26 | Tyco Healthcare Group Lp | Biocompatible surgical compositons |
| WO2007067764A2 (en) * | 2005-12-08 | 2007-06-14 | Tyco Healthcare Group Lp | Biocompatible surgical compositions |
| US8093039B2 (en) * | 2007-04-10 | 2012-01-10 | The Trustees Of The Stevens Institute Of Technology | Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells |
| US8207264B2 (en) * | 2008-07-11 | 2012-06-26 | Tyco Healthcare Group Lp | Functionalized inclusion complexes as crosslinkers |
| FI20095084A0 (fi) * | 2009-01-30 | 2009-01-30 | Pekka Vallittu | Komposiitti ja sen käyttö |
| EP2438908A1 (en) | 2010-10-11 | 2012-04-11 | Vectum Pharma, S.L. | Anchoring compositions for topical applications |
| RU2014128291A (ru) * | 2011-12-12 | 2016-02-10 | Агратек Интернешнл, Инк. | Гемостатический агент, способ остановки кровотечения и назальный спрей |
| WO2013103514A1 (en) | 2012-01-04 | 2013-07-11 | The Trustees Of The Stevens Institute Of Technology | Clay-containing thin films as carriers of absorbed molecules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH616694A5 (en) * | 1974-06-27 | 1980-04-15 | Ciba Geigy Ag | Process for the preparation of crosslinked, water-insoluble, hydrophilic copolymers |
| GB1551620A (en) * | 1976-12-13 | 1979-08-30 | Ici Ltd | Delivery means for biologically active agents |
| US4235988A (en) * | 1976-12-13 | 1980-11-25 | Imperial Chemical Industries Limited | Delivery means for biologically active agents |
| GB1551563A (en) * | 1977-09-19 | 1979-08-30 | Robinson G W | Board to play a ball and cue game with cue ball position indicators |
| JPH0739457B2 (ja) * | 1986-05-14 | 1995-05-01 | タキロン株式会社 | 両親媒性セグメントポリウレタン |
-
1987
- 1987-05-14 ES ES87106969T patent/ES2043619T3/es not_active Expired - Lifetime
- 1987-05-14 DE DE8787106969T patent/DE3780700T2/de not_active Expired - Lifetime
- 1987-05-14 EP EP87106969A patent/EP0245858B1/en not_active Expired
-
1989
- 1989-03-23 US US07/356,618 patent/US4997656A/en not_active Expired - Lifetime
-
1992
- 1992-10-15 GR GR920402308T patent/GR3005989T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3780700T2 (de) | 1993-02-04 |
| EP0245858A2 (en) | 1987-11-19 |
| DE3780700D1 (de) | 1992-09-03 |
| EP0245858A3 (en) | 1990-04-11 |
| GR3005989T3 (es) | 1993-06-07 |
| US4997656A (en) | 1991-03-05 |
| EP0245858B1 (en) | 1992-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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