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EP1624060A3 - Control of gene expression - Google Patents

Control of gene expression Download PDF

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Publication number
EP1624060A3
EP1624060A3 EP05013010A EP05013010A EP1624060A3 EP 1624060 A3 EP1624060 A3 EP 1624060A3 EP 05013010 A EP05013010 A EP 05013010A EP 05013010 A EP05013010 A EP 05013010A EP 1624060 A3 EP1624060 A3 EP 1624060A3
Authority
EP
European Patent Office
Prior art keywords
expression
gene expression
organism
organ
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP05013010A
Other languages
German (de)
French (fr)
Other versions
EP1624060A2 (en
EP1624060B1 (en
Inventor
Michael Wayne Graham
Robert Norman Rice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commonwealth Scientific and Industrial Research Organization CSIRO
Original Assignee
Commonwealth Scientific and Industrial Research Organization CSIRO
Benitec Australia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25645735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1624060(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from AUPP2499A external-priority patent/AUPP249998A0/en
Priority claimed from AUPP2492A external-priority patent/AUPP249298A0/en
Application filed by Commonwealth Scientific and Industrial Research Organization CSIRO, Benitec Australia Ltd filed Critical Commonwealth Scientific and Industrial Research Organization CSIRO
Publication of EP1624060A2 publication Critical patent/EP1624060A2/en
Publication of EP1624060A3 publication Critical patent/EP1624060A3/en
Application granted granted Critical
Publication of EP1624060B1 publication Critical patent/EP1624060B1/en
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

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    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable or repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.
EP05013010A 1998-03-20 1999-03-19 Control of gene expression Revoked EP1624060B1 (en)

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AUPP2499A AUPP249998A0 (en) 1998-03-20 1998-03-20 Gene expression I
AUPP2492A AUPP249298A0 (en) 1998-03-20 1998-03-20 Synthetic genes and genetic constructs comprising same I
EP99910039A EP1071762A4 (en) 1998-03-20 1999-03-19 GENE EXPRESSION CONTROL

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EP99910039A Division EP1071762A4 (en) 1998-03-20 1999-03-19 GENE EXPRESSION CONTROL
EP99910039.9 Division 1999-03-19

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EP1624060A2 EP1624060A2 (en) 2006-02-08
EP1624060A3 true EP1624060A3 (en) 2006-04-26
EP1624060B1 EP1624060B1 (en) 2011-09-28

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EP05013010A Revoked EP1624060B1 (en) 1998-03-20 1999-03-19 Control of gene expression
EP99910039A Ceased EP1071762A4 (en) 1998-03-20 1999-03-19 GENE EXPRESSION CONTROL
EP07008204.5A Expired - Lifetime EP1857549B1 (en) 1998-03-20 1999-03-19 Control of gene expression
EP04015041A Revoked EP1555317B1 (en) 1998-03-20 1999-03-19 Synthetic genes and genetic constructs comprising the same
EP10183258.2A Expired - Lifetime EP2302057B1 (en) 1998-03-20 1999-03-19 Control of gene expression

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EP99910039A Ceased EP1071762A4 (en) 1998-03-20 1999-03-19 GENE EXPRESSION CONTROL
EP07008204.5A Expired - Lifetime EP1857549B1 (en) 1998-03-20 1999-03-19 Control of gene expression
EP04015041A Revoked EP1555317B1 (en) 1998-03-20 1999-03-19 Synthetic genes and genetic constructs comprising the same
EP10183258.2A Expired - Lifetime EP2302057B1 (en) 1998-03-20 1999-03-19 Control of gene expression

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AT (2) ATE526406T1 (en)
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