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EP1218030A4 - METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF GRAFT REJECTS USING THERMAL SHOCK PROTEINS - Google Patents

METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF GRAFT REJECTS USING THERMAL SHOCK PROTEINS

Info

Publication number
EP1218030A4
EP1218030A4 EP00961701A EP00961701A EP1218030A4 EP 1218030 A4 EP1218030 A4 EP 1218030A4 EP 00961701 A EP00961701 A EP 00961701A EP 00961701 A EP00961701 A EP 00961701A EP 1218030 A4 EP1218030 A4 EP 1218030A4
Authority
EP
European Patent Office
Prior art keywords
prevention
compositions
treatment
methods
thermal shock
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP00961701A
Other languages
German (de)
French (fr)
Other versions
EP1218030A1 (en
Inventor
Pramod K Srivastava
Rajiv Y Chandawarkar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordham University
Original Assignee
Fordham University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordham University filed Critical Fordham University
Publication of EP1218030A1 publication Critical patent/EP1218030A1/en
Publication of EP1218030A4 publication Critical patent/EP1218030A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6043—Heat shock proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/622—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier non-covalent binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP00961701A 1999-09-10 2000-09-08 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF GRAFT REJECTS USING THERMAL SHOCK PROTEINS Withdrawn EP1218030A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39365299A 1999-09-10 1999-09-10
US393652 1999-09-10
PCT/US2000/024711 WO2001017554A1 (en) 1999-09-10 2000-09-08 Methods and compositions for the treatment and prevention of graft rejection using heat shock proteins

Publications (2)

Publication Number Publication Date
EP1218030A1 EP1218030A1 (en) 2002-07-03
EP1218030A4 true EP1218030A4 (en) 2004-09-15

Family

ID=23555669

Family Applications (1)

Application Number Title Priority Date Filing Date
EP00961701A Withdrawn EP1218030A4 (en) 1999-09-10 2000-09-08 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF GRAFT REJECTS USING THERMAL SHOCK PROTEINS

Country Status (4)

Country Link
EP (1) EP1218030A4 (en)
AU (1) AU7361900A (en)
CA (1) CA2383213A1 (en)
WO (1) WO2001017554A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495347B1 (en) 1999-07-08 2002-12-17 Stressgen Biotechnologies Corporation Induction of a Th1-like response in vitro
PL359930A1 (en) 2000-06-26 2004-09-06 Stressgen Biotechnologies Corporation Human papilloma virus treatment
EP1357940A4 (en) 2001-02-05 2004-03-17 Stressgen Biotechnologies Corp Hepatitis b virus treatment
WO2003096967A2 (en) 2002-05-21 2003-11-27 Yeda Research And Development Co. Ltd. Dna vaccines encoding heat shock proteins
AU2002952492A0 (en) 2002-11-06 2002-11-21 Cbio Limited Chaperonin 10 immunosuppression
US7745578B2 (en) * 2003-07-07 2010-06-29 The General Hospital Corporation Fugetactic proteins, compositions and methods of use
EP2428801B1 (en) 2006-03-14 2014-05-07 Oregon Health and Science University Methods for detecting a mycobacterium tuberculosis infection
EP2918598B1 (en) 2007-02-28 2019-01-30 The Govt. Of U.S.A. As Represented By The Secretary Of The Department Of Health And Human Services Brachyury polypeptides and methods for use
CA3004867C (en) 2008-06-26 2020-09-15 Orphazyme Aps Use of hsp70 as a regulator of enzymatic activity
WO2010099472A2 (en) 2009-02-27 2010-09-02 The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services Spanx-b polypeptides and their use
CN102462841A (en) * 2010-11-09 2012-05-23 中国科学院微生物研究所 Method for promoting immunological activity of gp96 protein and application thereof
JP2013544263A (en) 2010-11-30 2013-12-12 オルファザイム エーピーエス Method for increasing intracellular activity of Hsp70
EP2895191B1 (en) 2012-09-14 2019-06-05 The U.S.A. as represented by the Secretary, Department of Health and Human Services Brachyury protein, adenoviral vectors encoding brachyury protein, and their use
BR102014002362A8 (en) 2014-01-30 2018-04-17 Uniao Brasileira De Educacao E Assistencia Mantenedora Da Puc Rs method of immunomodulation and / or preservation of ex vivo organs, compositions, process and uses
JP6678676B2 (en) 2014-09-15 2020-04-08 オーファザイム エー／エス Arimoclomol formulation
EP4137150A1 (en) 2015-08-03 2023-02-22 The United States of America, as represented by the Secretary, Department of Health and Human Services Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use
EP3442530A1 (en) 2016-04-13 2019-02-20 Orphazyme A/S Heat shock proteins and cholesterol homeostasis
PT3448382T (en) 2016-04-29 2020-11-20 Orphazyme As C/O Cobis As Arimoclomol for treating glucocerebrosidase associated disorders
IL303026A (en) 2020-11-19 2023-07-01 Zevra Denmark As Processes for preparing arimoclomol citrate and its intermediates

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891653A (en) * 1995-12-29 1999-04-06 Attfield; Derrick Cecil Method of suppressing graft rejection by means of stress proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891653A (en) * 1995-12-29 1999-04-06 Attfield; Derrick Cecil Method of suppressing graft rejection by means of stress proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DUQUESNOY R J ET AL: "Evidence for heat shock protein immunity in a rat cardiac allograft model of chronic rejection", TRANSPLANTATION 15 JAN 1999 UNITED STATES, vol. 67, no. 1, 15 January 1999 (1999-01-15), pages 156 - 164, XP008032921, ISSN: 0041-1337 *
QIAN J ET AL: "Expression of stress proteins and lymphocyte reactivity in heterotopic cardiac allografts undergoing cellular rejection", TRANSPLANT IMMUNOLOGY 1995 UNITED KINGDOM, vol. 3, no. 2, 1995, pages 114 - 123, XP002288908, ISSN: 0966-3274 *
RIZZO MONICA ET AL: "Increased expression of HDJ-2 (heat shock protein 40) and heat shock protein 70 in biopsy specimens of transplanted human lungs", JOURNAL OF HEART AND LUNG TRANSPLANTATION, vol. 17, no. 3, March 1998 (1998-03-01), pages 241 - 249, XP008032559, ISSN: 1053-2498 *
See also references of WO0117554A1 *

Also Published As

Publication number Publication date
AU7361900A (en) 2001-04-10
WO2001017554A9 (en) 2002-09-26
CA2383213A1 (en) 2001-03-15
WO2001017554A1 (en) 2001-03-15
EP1218030A1 (en) 2002-07-03

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