EP0770094A4 - MODIFIED G PROTEIN-BINDING RECEPTORS - Google Patents

MODIFIED G PROTEIN-BINDING RECEPTORS

Info

Publication number: EP0770094A4
Authority: EP; European Patent Office
Prior art keywords: protein; modified; binding receptors; receptors; binding
Prior art date: 1994-06-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

EP95922156A

Other languages

German (de)

French (fr)

Other versions

EP0770094A1 (en

Inventor

Catherine D Strader

Candelore Maria-Luisa Rios

Xiaoming Guan

Richard Dixon

George Mcallister

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-29

Filing date

1995-06-02

Publication date

1999-05-19

1995-06-02 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

1997-05-02 Publication of EP0770094A1 publication Critical patent/EP0770094A1/en

1999-05-19 Publication of EP0770094A4 publication Critical patent/EP0770094A4/en

Status Withdrawn legal-status Critical Current

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Neurology (AREA)
Food Science & Technology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

EP95922156A 1994-06-29 1995-06-02 MODIFIED G PROTEIN-BINDING RECEPTORS Withdrawn EP0770094A4 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US26798794A	1994-06-29	1994-06-29
US26814794A	1994-06-29	1994-06-29
US267987		1994-06-29
PCT/US1995/006900 WO1996000739A1 (en)	1994-06-29	1995-06-02	Modified g-protein coupled receptors
US268147		1999-03-15

Publications (2)

Publication Number	Publication Date
EP0770094A1 EP0770094A1 (en)	1997-05-02
EP0770094A4 true EP0770094A4 (en)	1999-05-19

Family

ID=26952801

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EP95922156A Withdrawn EP0770094A4 (en)	1994-06-29	1995-06-02	MODIFIED G PROTEIN-BINDING RECEPTORS

Country Status (4)

Country	Link
EP (1)	EP0770094A4 (en)
JP (1)	JPH10502245A (en)
CA (1)	CA2193809A1 (en)
WO (1)	WO1996000739A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9606126D0 (en) *	1996-03-22	1996-05-22	British Biotech Pharm	Biosensors
WO2000012705A2 (en) *	1998-09-01	2000-03-09	Basf Aktiengesellschaft	Methods for improving the function of heterologous g protein-coupled receptors
US7094593B1 (en)	1998-09-01	2006-08-22	Basf Aktiengesellschaft	Method for improving the function of heterologous G protein-coupled receptors
WO2001087976A2 (en) *	2000-05-12	2001-11-22	3-Dimensional Pharmaceuticals, Inc.	Gpcr 4-helix and 5-helix bundles
EP2533046A1 (en)	2003-04-24	2012-12-12	Tyratech, Inc.	Screening method for compositions for controlling insects

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992001810A1 (en) *	1990-07-19	1992-02-06	Lerner Michael R	Methods of identifying compounds that act as agonists or antagonists for proteins involved in signal transduction

1995
- 1995-06-02 WO PCT/US1995/006900 patent/WO1996000739A1/en not_active Ceased
- 1995-06-02 EP EP95922156A patent/EP0770094A4/en not_active Withdrawn
- 1995-06-02 CA CA 2193809 patent/CA2193809A1/en not_active Abandoned
- 1995-06-02 JP JP8503165A patent/JPH10502245A/en active Pending

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992001810A1 (en) *	1990-07-19	1992-02-06	Lerner Michael R	Methods of identifying compounds that act as agonists or antagonists for proteins involved in signal transduction

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JIN H. ET AL.: "Characterization of the human 5-hydroxytryptamine 1B receptor", J. BIOL. CHEM., vol. 267, no. 9, 25 March 1992 (1992-03-25), pages 5735 - 5738, XP002096624 *
See also references of WO9600739A1 *
STRADER C.D. ET AL.: "Mutations that uncouple the beta-adrenergic receptor from Gs and increase agonist affinity.", J. BIOL. CHEM., vol. 262, no. 34, 5 December 1987 (1987-12-05), pages 16439 - 16443, XP002096623 *

Also Published As

Publication number	Publication date
JPH10502245A (en)	1998-03-03
WO1996000739A1 (en)	1996-01-11
EP0770094A1 (en)	1997-05-02
CA2193809A1 (en)	1996-01-11

Publication	Publication Date	Title
EP0791009A4 (en)	2003-03-05	MODIFIED NEUROPEPTIDE RECEPTORS
DE69635284D1 (en)	2006-02-23	NEW SUBSTITUTED NAPTHOPYRANEES
DE69635700D1 (en)	2006-03-30	NEW ENDOGLUKANASE
DE69512092D1 (en)	1999-10-14	JOINT MECHANISM
DE69536102D1 (en)	2010-10-21	NEW STREPTOGRAMINES
BR9607192A (en)	1997-11-11	Flexible tubular packaging
DE59801623D1 (en)	2001-11-08	Saddle stitcher
KR950030275U (en)	1995-11-20	Folding bicycle control
DE59504066D1 (en)	1998-12-03	HIGHLY RESISTANT MOLDED PARTS
EP0770094A4 (en)	1999-05-19	MODIFIED G PROTEIN-BINDING RECEPTORS
FIU960326U0 (en)	1996-05-29	A piston mechanism
DE69622801D1 (en)	2002-09-12	NEW CARBAPEN DERIVATIVES
EP0873409A4 (en)	2001-04-18	EQUIN RHINOVIRUS PROTEINS 1
EP0797446A4 (en)	2004-10-20	PROTEINS ASSOCIATED WITH CD40
FR2731733B1 (en)	1997-06-06	HAND PORTABLE PARPAING
FI972407A7 (en)	1997-06-06	Configuration mechanism
DE59602851D1 (en)	1999-09-30	Folding cylinder
DE69816638D1 (en)	2003-08-28	FLEXIBLE LENS
NO944204D0 (en)	1994-11-04	A choke
FIU960240U0 (en)	1996-04-15	A stop mechanism
NO962858D0 (en)	1996-07-05	Pose Binding Machine
DK23695A (en)	1996-09-08	A joint mechanism
FI945565A0 (en)	1994-11-25	A hand
KR970018515U (en)	1997-05-26	Rod material connecting mechanism
KR960036656U (en)	1996-12-16	Work stepping paper

Legal Events

Date	Code	Title	Description
1997-03-14	PUAI	Public reference made under article 153(3) epc to a published international application that has entered the european phase	Free format text: ORIGINAL CODE: 0009012
1997-05-02	17P	Request for examination filed	Effective date: 19970129
1997-05-02	AK	Designated contracting states	Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
1999-05-06	RHK1	Main classification (correction)	Ipc: C12N 15/63
1999-05-19	A4	Supplementary search report drawn up and despatched	Effective date: 19990401
1999-05-19	AK	Designated contracting states	Kind code of ref document: A4 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
2001-12-05	17Q	First examination report despatched	Effective date: 20011023
2002-09-21	STAA	Information on the status of an ep patent application or granted ep patent	Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN
2002-11-06	18D	Application deemed to be withdrawn	Effective date: 20020503