EP0118179A1 - Blisterverpackung - Google Patents
Blisterverpackung Download PDFInfo
- Publication number
- EP0118179A1 EP0118179A1 EP84300419A EP84300419A EP0118179A1 EP 0118179 A1 EP0118179 A1 EP 0118179A1 EP 84300419 A EP84300419 A EP 84300419A EP 84300419 A EP84300419 A EP 84300419A EP 0118179 A1 EP0118179 A1 EP 0118179A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- blister
- sheet
- strip pack
- lidding
- pack
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000010410 layer Substances 0.000 claims description 16
- 239000000123 paper Substances 0.000 claims description 15
- 239000000853 adhesive Substances 0.000 claims description 12
- 230000001070 adhesive effect Effects 0.000 claims description 10
- 239000002184 metal Substances 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 8
- 238000000576 coating method Methods 0.000 claims description 6
- 239000004816 latex Substances 0.000 claims description 5
- 229920000126 latex Polymers 0.000 claims description 5
- 239000012790 adhesive layer Substances 0.000 claims description 4
- 230000001464 adherent effect Effects 0.000 claims description 3
- 238000001771 vacuum deposition Methods 0.000 claims description 3
- 235000013311 vegetables Nutrition 0.000 claims description 3
- 239000004411 aluminium Substances 0.000 claims description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical group [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 2
- 229910052782 aluminium Inorganic materials 0.000 claims description 2
- 239000011086 glassine Substances 0.000 claims description 2
- 238000003475 lamination Methods 0.000 claims description 2
- 239000000203 mixture Substances 0.000 description 7
- 229920001169 thermoplastic Polymers 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000012856 packing Methods 0.000 description 4
- 239000004831 Hot glue Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000007850 degeneration Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000011121 hardwood Substances 0.000 description 2
- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 229920000915 polyvinyl chloride Polymers 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 229910021653 sulphate ion Inorganic materials 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 229920001131 Pulp (paper) Polymers 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 239000011088 parchment paper Substances 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/04—Articles or materials wholly enclosed in single sheets or wrapper blanks
- B65D75/20—Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/22—Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding the sheet or blank being recessed to accommodate contents
- B65D75/24—Articles or materials wholly enclosed in single sheets or wrapper blanks in sheets or blanks doubled around contents and having their opposed free margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding the sheet or blank being recessed to accommodate contents and formed with several recesses to accommodate a series of articles or quantities of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
- B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
Definitions
- This invention relates to a blister pack of the kind which can be used for packing various kinds of articles, and which is particularly although not exclusively applicable for packing medicines in the form of tablets, capsules or the like.
- blister pack consists of a polyvinyl chloride sheet which has been formed by heat and pressure into blisters.
- the articles to be packed are then placed in the blisters and a lidding sheet of aluminium foil applied over the flat surface of the blister sheet to seal the blisters.
- the lidding sheet is sealed to the blister sheet by various means, for example a hot melt adhesive in a heat sealing process. Because of the nature of the pack and the manufacturing process, it is only practicable to manufacture such packs under factory conditions. As a result: production is limited to the packaging of standard packs, for example aspirin tablets.
- the object of the present invention is to provide a blister pack incorporating a low cost lidding sheet which can be applied without the use of specialised apparatus, and which is cheap to produce.
- a blister or strip pack comprises a blister sheet which is formed to provide one or more blister cavities and a lidding sheet of paper adhered thereto to seal said cavity or cavities.
- the lidding sheet is preferably made from papers such as glassine; greaseproof, tracing or vegetable parchment which exhibit high burst and low tear resistance characteristics. Where it is desirable to heighten resistance to moisture transmission, this can be achieved by suitable treatment during manufacture of the paper or by applying coatings subsequently. Certain adhesives with which the paper may be coated for adhesion to the blister sheet may also provide this barrier property.
- the adhesion between the paper lidding and the blister sheet is such that the paper tears rather than peels from the blister sheet.
- the residual ruptured lidding fragments remaining when one blister has been opened tear off if attempts are made to peel them back to open another blister.
- the lidding sheet and the blister sheet are both provided with coatings of mutually adherent high tack dry latex adhesive. A layer of such adhesive will only adhere to another layer of the same adhesive, thus obviating the necessity to'provide protective release sheets.
- the lidding sheet and the blister sheet are both provided with coatings of high tack self-adhesive, each carrying a release sheet which can be stripped from the adhesive layer when the pack is to be assembled.
- the pack components do.not require factory conditions for assembly and can be put together by, for example, a pharmacist in a shop or hospital and used for packing tablets in a programmed dosage form.
- the lidding sheet may carry indicia and may be printed or typed upon prior to assembly so that dosage instructions specific to the patient can be set out on the pack.
- the lidding sheet of the invention may of course be used in a factory context if required.
- a hot melt adhesive is applied so that the lidding may be heat sealed, for example to polyvinyl chloride blister packs.
- a suitably coated lidding sheet according to the invention can be used with many forms of blister sheet material, for example a sheet material made from a blend of cellulose and synthetic wood pulp fibres as set forth in the Applicants co-pending EPA No. filed 24.01.1984 Ref W .87 corresponding to United Kingdom Patent Application No. 83 03600 filed 9th February 1983.
- the lidding paper can embody a metal layer. This can be provided either by lamination or vacuum deposition and it may for example be of aluminium. Where such a metallic layer is provided, a similar layer may be provided on the blister sheet.
- the blister sheet may be provided with any number of blister cavities appropriate to the number of articles to be packed.
- a blister sheet 1 is made from a mixture of cellulosic and fibrillated synthetic thermoplastic fibres as set forth in the Applicants co-pending EPA No. filed 24.01.1984 Ref W.87
- the synthetic fibres used are those sold under the Trade name SWP by Crown Zellerbach Corporation.
- the proportion of fibrillated thermoplastic polymer desirable in the paper sheet will vary with the deptch and configuration of the blister cavities to be formed.
- the thermoplastic polymer therefore is between 75% and 80% and is made up from approximately 75% fibrillated fibres and 25% particulate material.
- the remainder of the blend comprises the cellulosic and staple fibre material and this can be hardwood sulphate pulp.
- pigement such as titanium dioxide is also included.
- An alternative blend of materials suitable for the construction shown in Figures 1 and 2 comprises a blend of synthetic thermoplastic fibre material of the kind sold under the Trade name PULPEX EA by Solvay et Cie.
- high translucencey is achieved by including thermoplastic polymer amounting to about 85% of the blend, the remainder aqain being hardwood sulphate pulp.
- at least 60% of the thermoplastic polymer is in fibrillated form, the remainder being particulate.
- the sheet may be formed on a conventional papermaking machine and when it is to be made up into a blister sheet it is moulded by thermal deformation to provide blisters 2.
- the blister sheet 1 has coated thereon a layer of high tack dry latex adhesive 3 and contains within its blisters 3 drug tablets 4.
- a lidding sheet 5 carries thereon a layer 6 of the same high tack dry latex adhesive.
- the adhesive layers 3 and 6 are mutually adhesive but will not adhere to any other surface.
- The are sealed together at the locations 7 between the blisters so that each tablet 4 is isolated.
- the lidding sheet 5 is made of paper, and preferably of a paper having high burst and low tear resistance characteristics. This ensures that inadvertent rupture of the lidding sheet is minimised whilst ensuring that after intentional rupture, it will tear easily to release a selected tablet.
- Such papers are examplified by glassinge, greaseproof, tracing and vegetable parchment papers, burst and tear characteristics for which are set out in the following table
- FIG 3 shows a modification of the embodiment of Figures 1 and 2 particularly suited for packing articles 10 which are susceptible to ultra violet and/or hygroscopic degeneration.
- the construction and assembly of the blister pack is generally as described above with-reference to Figures 1 and 2 and where appropriate, the various parts are designated by the same reference numerals.
- the outer surfaces of the blister and lidding sheets 1 and 5 are provided with metal layers in 11 and 12 respectively.
- the metal layers are provided by vacuum deposition.
- the provision of a metal layer has a further advantage in that it renders both the blister pack and lidding sheet opaque and thus conceals the contents from children who might otherwise identify them as sweets or candies.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Chemical & Material Sciences (AREA)
- Composite Materials (AREA)
- Packages (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8303600 | 1983-02-09 | ||
| GB838303600A GB8303600D0 (en) | 1983-02-09 | 1983-02-09 | Blister sheet |
| GB8309231 | 1983-04-05 | ||
| GB8309231 | 1983-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP0118179A1 true EP0118179A1 (de) | 1984-09-12 |
Family
ID=26285178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP84300419A Withdrawn EP0118179A1 (de) | 1983-02-09 | 1984-01-24 | Blisterverpackung |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0118179A1 (de) |
| AU (1) | AU2420684A (de) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2174070A (en) * | 1985-04-15 | 1986-10-29 | Boxall Company | Blister packs |
| GB2242134B (en) * | 1990-03-02 | 1994-10-19 | Glaxo Group Ltd | Inhalation device |
| US5622166A (en) * | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
| EP1157682A1 (de) * | 2000-05-25 | 2001-11-28 | Cilag AG | Blisterpackung für Topiramattabletten |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| US6792945B2 (en) | 1990-03-02 | 2004-09-21 | Glaxo Group Limited | Inhalation device |
| US7225808B2 (en) | 1990-03-02 | 2007-06-05 | Glaxo Group Limited | Inhalation device |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4653644A (en) * | 1984-06-18 | 1987-03-31 | Degesch Gmbh | Package for toxic fumigant material in pellet or tablet form and method of making same |
| US4911304A (en) * | 1989-03-20 | 1990-03-27 | Merck & Co., Inc. | Sandwich blister package for tablets and similar articles |
| AUPN673895A0 (en) * | 1995-11-23 | 1995-12-14 | Cruse, Peter Alan | A dispenser for toothpicks |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3202277A (en) * | 1964-03-19 | 1965-08-24 | Lewi William | Dual seal package |
| DE1276993B (de) * | 1955-10-13 | 1968-09-05 | Feldmuehle Ag | Gegen Licht und Wasserdampf weitgehend undurchlaessiges Verpackungsmaterial auf Zellulosebasis |
| US3630346A (en) * | 1970-06-01 | 1971-12-28 | Lilly Co Eli | Components for making a strip package |
| DE3029253A1 (de) * | 1980-08-01 | 1982-03-11 | Dixie-Union Verpackungen Gmbh, 8960 Kempten | Kindersichere arzneimittelverpackung |
-
1984
- 1984-01-24 EP EP84300419A patent/EP0118179A1/de not_active Withdrawn
- 1984-02-06 AU AU24206/84A patent/AU2420684A/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1276993B (de) * | 1955-10-13 | 1968-09-05 | Feldmuehle Ag | Gegen Licht und Wasserdampf weitgehend undurchlaessiges Verpackungsmaterial auf Zellulosebasis |
| US3202277A (en) * | 1964-03-19 | 1965-08-24 | Lewi William | Dual seal package |
| US3630346A (en) * | 1970-06-01 | 1971-12-28 | Lilly Co Eli | Components for making a strip package |
| DE3029253A1 (de) * | 1980-08-01 | 1982-03-11 | Dixie-Union Verpackungen Gmbh, 8960 Kempten | Kindersichere arzneimittelverpackung |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2174070A (en) * | 1985-04-15 | 1986-10-29 | Boxall Company | Blister packs |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| US7225808B2 (en) | 1990-03-02 | 2007-06-05 | Glaxo Group Limited | Inhalation device |
| US5860419A (en) * | 1990-03-02 | 1999-01-19 | Glaxo Group Limited | Inhalation device |
| US5873360A (en) * | 1990-03-02 | 1999-02-23 | Glaxo Group Limited | Inhalation device |
| US6032666A (en) * | 1990-03-02 | 2000-03-07 | Glaxo Group Limited | Inhalation device |
| US7389775B2 (en) | 1990-03-02 | 2008-06-24 | Glaxo Group Limited | Inhalation device |
| US5590645A (en) * | 1990-03-02 | 1997-01-07 | Glaxo Group Limited | Inhalation device |
| GB2242134B (en) * | 1990-03-02 | 1994-10-19 | Glaxo Group Ltd | Inhalation device |
| US6792945B2 (en) | 1990-03-02 | 2004-09-21 | Glaxo Group Limited | Inhalation device |
| US5622166A (en) * | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
| WO2001089445A1 (en) * | 2000-05-25 | 2001-11-29 | Cilag Ag | Blister package for topiramate tablets |
| AU777753B2 (en) * | 2000-05-25 | 2004-10-28 | Cilag A.G. | Blister package for topiramate tablets |
| EP1157682A1 (de) * | 2000-05-25 | 2001-11-28 | Cilag AG | Blisterpackung für Topiramattabletten |
| EP1284711B2 (de) † | 2000-05-25 | 2012-03-28 | Cilag AG | Verfahren zur herstellung einer blisterpackung für topiramattabletten |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2420684A (en) | 1984-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| AK | Designated contracting states |
Designated state(s): BE DE FR GB IT LU NL |
|
| 17P | Request for examination filed |
Effective date: 19841002 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
| 18D | Application deemed to be withdrawn |
Effective date: 19851015 |
|
| RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SCHWARTZ, GERHARD THOMAS Inventor name: INGLIS, BRUCE REYNOLDS |