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EE9500080A - Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon - Google Patents

Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Info

Publication number
EE9500080A
EE9500080A EE9500080A EE9500080A EE9500080A EE 9500080 A EE9500080 A EE 9500080A EE 9500080 A EE9500080 A EE 9500080A EE 9500080 A EE9500080 A EE 9500080A EE 9500080 A EE9500080 A EE 9500080A
Authority
EE
Estonia
Prior art keywords
preparation
pharmaceutical composition
composition containing
erythromycin derivatives
erythromycin
Prior art date
Application number
EE9500080A
Other languages
English (en)
Other versions
EE04498B1 (et
Inventor
Agouridas Constantin
Benedetti Yannick
Chantot Jean-Fran�Ois
Denis Alexis
Le Martret Odile
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of EE9500080A publication Critical patent/EE9500080A/et
Publication of EE04498B1 publication Critical patent/EE04498B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EE9500080A 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon EE04498B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
PCT/FR1995/000441 WO1995027720A1 (fr) 1994-04-08 1995-04-06 Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
EE9500080A true EE9500080A (et) 1996-12-16
EE04498B1 EE04498B1 (et) 2005-06-15

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9500080A EE04498B1 (et) 1994-04-08 1995-04-06 Erütromütsiini derivaadid, nende valmistamismeetod ja neid sisaldav farmatseutiline kompositsioon

Country Status (49)

Country Link
US (2) US5656607A (et)
EP (1) EP0676409B1 (et)
JP (1) JP3000023B2 (et)
KR (1) KR100317148B1 (et)
CN (1) CN1059445C (et)
AP (1) AP587A (et)
AT (1) ATE234853T1 (et)
AU (1) AU684939B2 (et)
BG (1) BG61916B1 (et)
BR (1) BR9506147A (et)
CA (1) CA2164638C (et)
CO (1) CO4370097A1 (et)
CZ (1) CZ296005B6 (et)
DE (1) DE69529934T2 (et)
DK (1) DK0676409T3 (et)
DZ (1) DZ1869A1 (et)
EE (1) EE04498B1 (et)
ES (1) ES2189820T3 (et)
FI (1) FI111264B (et)
FR (1) FR2718450B1 (et)
GB (1) GB2288174A (et)
GE (1) GEP19991836B (et)
HR (1) HRP950217B1 (et)
HU (1) HU215396B (et)
IL (1) IL112954A (et)
IS (1) IS1865B (et)
JO (1) JO1850B1 (et)
LV (1) LV11182B (et)
MA (1) MA23501A1 (et)
MD (1) MD663G2 (et)
MY (1) MY114672A (et)
NO (1) NO308361B1 (et)
NZ (1) NZ284498A (et)
OA (1) OA10200A (et)
PE (1) PE2896A1 (et)
PL (1) PL180837B1 (et)
PT (1) PT676409E (et)
RO (1) RO115634B1 (et)
RU (1) RU2141965C1 (et)
SA (1) SA97170757A (et)
SI (1) SI0676409T1 (et)
SK (1) SK284079B6 (et)
SV (1) SV1995000018A (et)
TN (1) TNSN95026A1 (et)
TW (1) TW316908B (et)
UA (1) UA44705C2 (et)
WO (1) WO1995027720A1 (et)
YU (1) YU49221B (et)
ZA (1) ZA952059B (et)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2745289B1 (fr) * 1996-02-28 1998-05-29 Roussel Uclaf Nouveaux derives de l'acide 1(2h) quinoleine carboxylique, leur procede de preparation et leur application a la synthese de produits doues de proprietes antibiotiques
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
DK0922050T3 (da) * 1996-05-07 2003-11-24 Abbott Lab 3-Descladinose-2,3-anhydroerythromycin-derivater
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
KR100576988B1 (ko) * 1996-09-04 2006-05-10 아보트 러보러터리즈 항균 활성을 지닌 6-o-치환된 케톨라이드
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
AU4472897A (en) * 1997-03-10 1998-09-29 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
AU6932098A (en) * 1997-05-09 1998-12-08 Pfizer Products Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
KR20010013660A (ko) * 1997-06-11 2001-02-26 실버스타인 아써 에이. 9-옥심 에리트로마이신 유도체
FR2771008B1 (fr) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
ATE298761T1 (de) * 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
DE69933897T2 (de) 1998-12-10 2007-03-15 Pfizer Products Inc., Groton Carbamat- und Carbazatketolid-Antibiotika
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
EP1171447A2 (en) 1999-04-16 2002-01-16 Ortho-McNeil Pharmaceutical, Inc. Ketolide antibacterials
NZ515027A (en) * 1999-04-16 2004-01-30 Kosan Biosciences Inc Erythromycin derivatives as antibiotics
CN1351608A (zh) * 1999-05-24 2002-05-29 辉瑞产品公司 13-甲基红霉素衍生物
AU2002316550A1 (en) 2001-07-03 2003-01-21 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
JP2006508643A (ja) 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー/ビー/エー バイオ−テクニカル リソーセズ ディビジョン グルコサミンおよびn−アセチルグルコサミン製造のためのプロセスおよび材料
EP3738591A3 (en) * 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
WO2004096822A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Pyridyl substituted ketolide antibiotics
WO2004096823A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Novel ketolide derivatives
WO2009055557A1 (en) * 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
DK2358379T3 (en) 2008-10-24 2016-03-07 Cempra Pharmaceuticals Inc BIOFORSVAR USING TRIAZOLHOLDIGE macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
JP5711352B2 (ja) 2010-03-22 2015-04-30 センプラ ファーマシューティカルズ,インコーポレイテッド マクロライドの結晶形、およびその使用
WO2011146829A1 (en) 2010-05-20 2011-11-24 Cempra Pharmaceuticals, Inc. Processes for preparing macrolides and ketolides and intermediates therefor
US9815863B2 (en) 2010-09-10 2017-11-14 Cempra Pharmaceuticals, Inc. Hydrogen bond forming fluoro ketolides for treating diseases
US10188674B2 (en) 2012-03-27 2019-01-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
CA3130061C (en) 2013-04-04 2024-05-28 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
WO2016057798A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
AT342770B (de) * 1975-04-07 1978-04-25 Thomae Gmbh Dr K Verfahren zur herstellung neuer erythromycinderivate
DE2842759A1 (de) * 1978-09-30 1980-04-10 Merck Patent Gmbh Basische aether, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of erythromycin derivatives
FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
NZ284498A (en) 1997-07-27
MD663G2 (ro) 1997-07-31
RU2141965C1 (ru) 1999-11-27
OA10200A (fr) 1996-12-18
TNSN95026A1 (fr) 1996-02-06
DK0676409T3 (da) 2003-06-23
AP587A (en) 1997-04-29
IS4309A (is) 1995-11-17
UA44705C2 (uk) 2002-03-15
FR2718450A1 (fr) 1995-10-13
FR2718450B1 (fr) 1997-01-10
HU215396B (hu) 1998-12-28
JP3000023B2 (ja) 2000-01-17
LV11182B (en) 1997-04-20
MA23501A1 (fr) 1995-12-31
WO1995027720A1 (fr) 1995-10-19
CA2164638C (fr) 2003-12-30
DE69529934D1 (de) 2003-04-24
EE04498B1 (et) 2005-06-15
EP0676409B1 (fr) 2003-03-19
ZA952059B (en) 1996-03-13
BG61916B1 (bg) 1998-09-30
CN1059445C (zh) 2000-12-13
PL180837B1 (pl) 2001-04-30
NO954942D0 (no) 1995-12-06
HRP950217A2 (en) 1997-08-31
MD663F1 (ro) 1997-01-31
HRP950217B1 (en) 2004-06-30
JO1850B1 (en) 1995-12-27
IL112954A (en) 2000-07-16
SV1995000018A (es) 1997-10-24
FI111264B (fi) 2003-06-30
YU21695A (sh) 1997-12-05
ES2189820T3 (es) 2003-07-16
DZ1869A1 (fr) 2002-02-17
CO4370097A1 (es) 1996-10-07
IL112954A0 (en) 1995-06-29
BR9506147A (pt) 1996-04-16
SA97170757A (ar) 2005-12-03
EP0676409A1 (fr) 1995-10-11
CZ296005B6 (cs) 2005-12-14
AP9500743A0 (en) 1995-07-31
FI955913A7 (fi) 1995-12-08
US5760233A (en) 1998-06-02
AU684939B2 (en) 1998-01-08
IS1865B (is) 2003-05-02
PE2896A1 (es) 1996-02-12
US5656607A (en) 1997-08-12
CA2164638A1 (fr) 1995-10-19
KR100317148B1 (ko) 2002-06-22
JPH07278177A (ja) 1995-10-24
CN1126997A (zh) 1996-07-17
PL311871A1 (en) 1996-03-18
GEP19991836B (en) 1999-11-05
SK154695A3 (en) 1996-10-02
AU2310795A (en) 1995-10-30
FI955913A0 (fi) 1995-12-08
CZ322395A3 (en) 1996-08-14
ATE234853T1 (de) 2003-04-15
HUT73772A (en) 1996-09-30
NO954942L (no) 1996-02-07
RO115634B1 (ro) 2000-04-28
DE69529934T2 (de) 2003-09-04
YU49221B (sh) 2004-11-25
HU9503505D0 (en) 1996-02-28
SI0676409T1 (en) 2003-06-30
PT676409E (pt) 2003-08-29
LV11182A (lv) 1996-04-20
BG100150A (bg) 1996-06-28
SK284079B6 (sk) 2004-09-08
TW316908B (et) 1997-10-01
NO308361B1 (no) 2000-09-04
MY114672A (en) 2002-12-31
GB9506856D0 (en) 1995-05-24
GB2288174A (en) 1995-10-11

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