EE200300394A - GlyT-1 inhibiitorid - Google Patents

GlyT-1 inhibiitorid

Info

Publication number: EE200300394A
Authority: EE; Estonia
Prior art keywords: glyt; inhibitors; neurological; pharmaceutical; compound
Prior art date: 2001-02-16

Application number

EEP200300394A

Other languages

English (en)

Inventor

Egle Ian

Delaney William

Wang Zhaoqing

Shumacher Richard

T. Hopper Allen

Tehim Ashok

Maddaford Shawn

Original Assignee

Allelix Neuroscience, Inc.

Nps Allelix Corp.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-16

Filing date

2002-02-15

Publication date

2003-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23026417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE200300394(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2002-02-15 Application filed by Allelix Neuroscience, Inc., Nps Allelix Corp. filed Critical Allelix Neuroscience, Inc.

2003-12-15 Publication of EE200300394A publication Critical patent/EE200300394A/et

2010-08-16 Publication of EE05329B1 publication Critical patent/EE05329B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

EEP200300394A 2001-02-16 2002-02-15 GlyT-1 inhibiitorid, neid sisaldavad kompositsioonid, nende kasutamine ja nende valmistamise vahehendid EE05329B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26924101P	2001-02-16	2001-02-16
PCT/CA2002/000176 WO2002066456A2 (en)	2001-02-16	2002-02-15	Thiophene substituted amine derivatives as glyt-1 inhibitors

Publications (2)

Publication Number	Publication Date
EE200300394A true EE200300394A (et)	2003-12-15
EE05329B1 EE05329B1 (et)	2010-08-16

Family

ID=23026417

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300394A EE05329B1 (et)	2001-02-16	2002-02-15	GlyT-1 inhibiitorid, neid sisaldavad kompositsioonid, nende kasutamine ja nende valmistamise vahehendid

Country Status (30)

Country	Link
US (1)	US6667336B2 (et)
EP (1)	EP1368336B9 (et)
JP (2)	JP2004523548A (et)
KR (1)	KR100900020B1 (et)
CN (1)	CN1219776C (et)
AT (1)	ATE327986T1 (et)
AU (1)	AU2002235682C1 (et)
BG (1)	BG108164A (et)
BR (1)	BR0207307A (et)
CA (1)	CA2438367A1 (et)
CY (1)	CY1105529T1 (et)
CZ (1)	CZ20032503A3 (et)
DE (1)	DE60211866T2 (et)
DK (1)	DK1368336T3 (et)
EA (1)	EA006636B1 (et)
EE (1)	EE05329B1 (et)
ES (1)	ES2266446T3 (et)
HR (1)	HRP20030696A2 (et)
HU (1)	HUP0303185A3 (et)
IL (1)	IL157194A (et)
MX (1)	MXPA03007309A (et)
NO (1)	NO329038B1 (et)
NZ (1)	NZ527695A (et)
PL (1)	PL365024A1 (et)
PT (1)	PT1368336E (et)
SI (1)	SI1368336T1 (et)
SK (1)	SK287304B6 (et)
UA (1)	UA75114C2 (et)
WO (1)	WO2002066456A2 (et)
ZA (1)	ZA200307201B (et)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6191165B1 (en) *	1996-05-31	2001-02-20	Allelix Neuroscience Inc.	Pharmaceutical for treatment of neurological and neuropsychiatric disorders
ATE456366T1 (de) *	2004-12-16	2010-02-15	Janssen Pharmaceutica Nv	Kombination aus einem glycin-transporter (glyt1) hemmer und einem antipsychotikum zur behandlung von symptomen von schizophrenie und ihre herstellung und verwendung
WO2008040669A2 (en) *	2006-10-02	2008-04-10	Janssen Pharmaceutica N.V.	Novel intermediates for the preparation of a glyt1 inhibitor
WO2008065500A2 (en) *	2006-11-30	2008-06-05	Pfizer Products Inc.	Heteroaryl amides as type i glycine transport inhibitors
CN103374057B (zh) *	2012-04-16	2015-08-19	中国医药集团总公司四川抗菌素工业研究所	一种对甘氨酸转运子具有抑制活性的化合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3010599A1 (de)	1979-03-22	1980-10-09	Continental Pharma	Derivate von glycinamid, deren herstellung und verwendung
BE885303A (fr)	1980-09-19	1981-03-19	Continental Pharma	Glycinamides
US4383999A (en)	1981-05-26	1983-05-17	Smithkline Beckman Corporation	Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
AU552050B2 (en)	1981-05-26	1986-05-22	Smithkline Beckman Corporation	N-substituted azeheterocyclic carboxylic acids and their esters
US4514414A (en)	1982-10-25	1985-04-30	Smithkline Beckman Corporation	N-Substituted pyrrolidineacetic acids and their esters
DK288385D0 (da)	1985-06-26	1985-06-26	Novo Industri As	Aminosyrederivater
US4772615A (en)	1985-11-08	1988-09-20	Warner-Lambert Company	Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof
FI864246A7 (fi)	1985-11-08	1987-05-09	Warner Lambert Co	N-substituerade 3-piperidin- eller 3-pyridinkarboxylsyror samt deras derivat.
NO170976C (no)	1986-01-07	1993-01-06	Novo Nordisk As	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylbuten-syrederivater
JPH02129158A (ja)	1988-11-07	1990-05-17	Nippon Steel Corp	光学活性なグリシン誘導体及びその製造方法
IE913279A1 (en) *	1990-09-26	1992-04-08	Astra Ab	(2-Thienyl)alkylamine Derivatives Having Neuroprotective¹Properties
ES2036926B1 (es)	1991-08-08	1994-01-16	Uriach & Cia Sa J	"procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
WO1997020553A1 (en)	1995-12-07	1997-06-12	Javitt Daniel C	Treatment of negative and cognitive symptoms of schizophrenia with glycine uptake antagonists
SI1014966T1 (sl) *	1996-05-31	2006-10-31	Allelix Neuroscience Inc	Zdravilo za zdravljenje nevroloskih in nevripsihiatricnih bolezni
US6191165B1 (en)	1996-05-31	2001-02-20	Allelix Neuroscience Inc.	Pharmaceutical for treatment of neurological and neuropsychiatric disorders
JP4425992B2 (ja) *	1996-07-22	2010-03-03	サファイアセラピューティクス，インコーポレイティド	成長ホルモン放出特性を有する化合物
PT1047665E (pt) *	1998-01-09	2004-01-30	Pfizer	Inibidores de metaloproteases de matriz
US6103743A (en) *	1999-08-06	2000-08-15	Allelix Neuroscience, Inc.	Unsaturated amino acid derivatives

2002
- 2002-02-15 CN CNB028050819A patent/CN1219776C/zh not_active Expired - Fee Related
- 2002-02-15 AT AT02702186T patent/ATE327986T1/de not_active IP Right Cessation
- 2002-02-15 CZ CZ20032503A patent/CZ20032503A3/cs unknown
- 2002-02-15 SK SK1144-2003A patent/SK287304B6/sk not_active IP Right Cessation
- 2002-02-15 DK DK02702186T patent/DK1368336T3/da active
- 2002-02-15 DE DE60211866T patent/DE60211866T2/de not_active Expired - Lifetime
- 2002-02-15 ES ES02702186T patent/ES2266446T3/es not_active Expired - Lifetime
- 2002-02-15 WO PCT/CA2002/000176 patent/WO2002066456A2/en not_active Ceased
- 2002-02-15 EA EA200300900A patent/EA006636B1/ru not_active IP Right Cessation
- 2002-02-15 EE EEP200300394A patent/EE05329B1/et not_active IP Right Cessation
- 2002-02-15 HU HU0303185A patent/HUP0303185A3/hu unknown
- 2002-02-15 CA CA002438367A patent/CA2438367A1/en not_active Abandoned
- 2002-02-15 AU AU2002235682A patent/AU2002235682C1/en not_active Ceased
- 2002-02-15 SI SI200230381T patent/SI1368336T1/sl unknown
- 2002-02-15 EP EP02702186A patent/EP1368336B9/en not_active Expired - Lifetime
- 2002-02-15 NZ NZ527695A patent/NZ527695A/en unknown
- 2002-02-15 UA UA2003087630A patent/UA75114C2/uk unknown
- 2002-02-15 PT PT02702186T patent/PT1368336E/pt unknown
- 2002-02-15 BR BR0207307-2A patent/BR0207307A/pt not_active IP Right Cessation
- 2002-02-15 JP JP2002565971A patent/JP2004523548A/ja active Pending
- 2002-02-15 HR HR20030696A patent/HRP20030696A2/xx not_active Application Discontinuation
- 2002-02-15 US US10/077,579 patent/US6667336B2/en not_active Expired - Fee Related
- 2002-02-15 KR KR1020037010609A patent/KR100900020B1/ko not_active Expired - Fee Related
- 2002-02-15 MX MXPA03007309A patent/MXPA03007309A/es active IP Right Grant
- 2002-02-15 PL PL02365024A patent/PL365024A1/xx unknown
2003
- 2003-07-31 IL IL157194A patent/IL157194A/en not_active IP Right Cessation
- 2003-08-15 NO NO20033634A patent/NO329038B1/no not_active IP Right Cessation
- 2003-09-09 BG BG108164A patent/BG108164A/xx unknown
- 2003-09-15 ZA ZA200307201A patent/ZA200307201B/en unknown
2006
- 2006-08-22 CY CY20061101160T patent/CY1105529T1/el unknown
2009
- 2009-11-09 JP JP2009255663A patent/JP2010059182A/ja active Pending

Also Published As

Publication number	Publication date
BR0207307A (pt)	2004-08-17
DE60211866D1 (de)	2006-07-06
EP1368336B9 (en)	2007-02-14
EE05329B1 (et)	2010-08-16
CZ20032503A3 (cs)	2004-02-18
EP1368336A2 (en)	2003-12-10
EA200300900A1 (ru)	2004-02-26
ES2266446T3 (es)	2007-03-01
ZA200307201B (en)	2004-07-28
AU2002235682B2 (en)	2007-04-26
WO2002066456A2 (en)	2002-08-29
SK287304B6 (sk)	2010-06-07
PT1368336E (pt)	2006-10-31
BG108164A (en)	2004-07-30
CN1219776C (zh)	2005-09-21
DE60211866T2 (de)	2007-06-14
US20030176489A1 (en)	2003-09-18
DK1368336T3 (da)	2006-10-02
NO20033634L (no)	2003-10-08
HK1061025A1 (en)	2004-09-03
HUP0303185A2 (hu)	2003-12-29
PL365024A1 (en)	2004-12-27
EP1368336B1 (en)	2006-05-31
NO329038B1 (no)	2010-08-02
MXPA03007309A (es)	2004-06-30
ATE327986T1 (de)	2006-06-15
EA006636B1 (ru)	2006-02-24
AU2002235682C1 (en)	2008-12-11
JP2010059182A (ja)	2010-03-18
SK11442003A3 (sk)	2004-03-02
NZ527695A (en)	2005-05-27
HUP0303185A3 (en)	2008-12-29
CY1105529T1 (el)	2010-07-28
UA75114C2 (en)	2006-03-15
KR100900020B1 (ko)	2009-06-01
JP2004523548A (ja)	2004-08-05
CA2438367A1 (en)	2002-08-29
KR20040028719A (ko)	2004-04-03
SI1368336T1 (sl)	2006-10-31
CN1491221A (zh)	2004-04-21
US6667336B2 (en)	2003-12-23
WO2002066456A3 (en)	2002-10-17
NO20033634D0 (no)	2003-08-15
IL157194A (en)	2006-12-31
HRP20030696A2 (en)	2005-04-30

Publication	Publication Date	Title
DK1014966T3 (da)	2006-12-04	Farmaceutisk præparat til behandling af neurologiske og neuropsykiatriske lidelser
ATE440603T1 (de)	2009-09-15	8-hydroxychinolinderivate
ATE371656T1 (de)	2007-09-15	Heteroaryl-pyrimidinderivate als jak-inhibitoren
SE0101932D0 (sv)	2001-05-31	Pharmaceutical combinations
PT1411926E (pt)	2005-10-31	Inibidores de integrina para o tratamento de doencas oftalmicas
IS6087A (is)	2001-09-26	N-(2-fenýl-4-amínó-bútýl)-1-naftamíð sem virka á móti taugakínín-1 viðtaka
DE69917005D1 (de)	2004-06-09	Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung
NO20033634D0 (no)	2003-08-15	GLYT-1 inhibitorer
MXPA05014143A (es)	2006-02-24	Derivados de cumarina para el tratamiento de trastornos oftalmicos.
SE0004827D0 (sv)	2000-12-22	Therapeutic compounds
TNSN99158A1 (ar)	2005-11-10	طريقة لمنع الاصابة بالربو
TNSN05154A1 (en)	2007-05-14	Use of levocetirizine for the treatment of persistent allergic rhinitis
SE0100295D0 (sv)	2001-02-01	New compounds
ZA200400824B (en)	2004-07-20	Pyridin-2-yl-methlyamine derivatives for treating opioid dependence.

Legal Events

Date	Code	Title	Description
2008-10-15	GB1A	Change in the ownership or in the address of the owner
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2011-10-17	MM4A	Lapsed by not paying the annual fees	Effective date: 20110215