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EE200200583A - (E)-N-(6,6-dimetüül-2-hepteen-4-ünüül)-N-metüül-1-naftaleenmetaanamiini (terbinafiin) valmistamise meetod - Google Patents

(E)-N-(6,6-dimetüül-2-hepteen-4-ünüül)-N-metüül-1-naftaleenmetaanamiini (terbinafiin) valmistamise meetod

Info

Publication number
EE200200583A
EE200200583A EEP200200583A EEP200200583A EE200200583A EE 200200583 A EE200200583 A EE 200200583A EE P200200583 A EEP200200583 A EE P200200583A EE P200200583 A EEP200200583 A EE P200200583A EE 200200583 A EE200200583 A EE 200200583A
Authority
EE
Estonia
Prior art keywords
naphthalenemethanamine
hepten
terbinafine
ynyl
dimethyl
Prior art date
Application number
EEP200200583A
Other languages
English (en)
Inventor
Kakal�k Ivan
Oremus Vladim�r
�mahovsk Vendel
�nup�rek Vladislav
Vand�k Du�an
Varga Ivan
Zem�nek Mari�n
�talmach Valdemar
Jezek Ladislav
Original Assignee
Slovakofarma A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slovakofarma A.S. filed Critical Slovakofarma A.S.
Publication of EE200200583A publication Critical patent/EE200200583A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
EEP200200583A 2000-04-07 2001-04-05 (E)-N-(6,6-dimetüül-2-hepteen-4-ünüül)-N-metüül-1-naftaleenmetaanamiini (terbinafiin) valmistamise meetod EE200200583A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK520-2000A SK5202000A3 (en) 2000-04-07 2000-04-07 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
PCT/SK2001/000008 WO2001077064A1 (en) 2000-04-07 2001-04-05 Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamine (terbinafine)

Publications (1)

Publication Number Publication Date
EE200200583A true EE200200583A (et) 2004-04-15

Family

ID=20435846

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200583A EE200200583A (et) 2000-04-07 2001-04-05 (E)-N-(6,6-dimetüül-2-hepteen-4-ünüül)-N-metüül-1-naftaleenmetaanamiini (terbinafiin) valmistamise meetod

Country Status (7)

Country Link
AU (1) AU2001248998A1 (et)
EE (1) EE200200583A (et)
HU (1) HUP0302919A3 (et)
LT (1) LT5051B (et)
LV (1) LV12955B (et)
SK (1) SK5202000A3 (et)
WO (1) WO2001077064A1 (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100459275B1 (ko) * 2001-12-28 2004-12-03 주식회사유한양행 터비나핀 또는 그의 염산염의 제조방법
KR20030066186A (ko) * 2002-02-05 2003-08-09 한솔케미언스 주식회사 (ｅ)-터비나핀 또는 이의 염산염의 제조방법
ITMI20022534A1 (it) * 2002-11-29 2004-05-30 Dinamite Dipharma S P A Procedimento per la preparazione di terbinafina mediante l'uso di platino come catalizzatore.
EA014935B1 (ru) * 2005-10-31 2011-04-29 Янссен Фармацевтика Н.В. Способы получения производных циклопропиламида
WO2007053427A2 (en) * 2005-10-31 2007-05-10 Janssen Pharmaceutica N.V. Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives
CN101624328B (zh) * 2009-07-31 2011-12-14 山东铂源化学有限公司 (e)-1-氯-6,6-二甲基-2-庚烯-4-炔的合成方法
CN104725240B (zh) * 2015-02-12 2017-05-24 吉林修正药业新药开发有限公司 一种盐酸特比萘芬z型异构体的制备方法
CN105016966A (zh) * 2015-07-31 2015-11-04 江苏恒润制药有限公司 一种（e）-1-氯-6,6-二甲基-2-庚烯-4-炔的制备方法
CN111153807B (zh) * 2020-01-16 2023-01-06 河南豫辰药业股份有限公司 一种n,n-二甲氨基氯丙烷盐酸盐的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3069633D1 (en) 1979-08-22 1984-12-20 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
CH678527A5 (en) 1989-06-22 1991-09-30 Sandoz Ag Trans(E)-N-(1-naphthyl:methyl)-heptenyl-amine prepn. - by simultaneously converting crude mixt. contg. cis and trans isomers to salt and precipitating trans isomer
JP3116364B2 (ja) 1989-10-02 2000-12-11 萬有製薬株式会社 エンイン誘導体の製造法
NZ280065A (en) 1995-09-20 1998-04-27 Apotex Inc Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives

Also Published As

Publication number Publication date
HUP0302919A3 (en) 2004-09-28
LV12955B (en) 2003-04-20
LT5051B (lt) 2003-08-25
AU2001248998A1 (en) 2001-10-23
WO2001077064A1 (en) 2001-10-18
SK5202000A3 (en) 2001-12-03
LT2002103A (en) 2003-05-26
WO2001077064A8 (en) 2002-01-03
HUP0302919A2 (hu) 2003-12-29

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