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EE200200507A - Muundatud vaktsiiniaviirus Ankara (MVA), sellega nakatatud peremeesrakk ning seda sisaldav farmatseutiline kompositsioon, MVA valmistamine ja raviotstarbeline kasutamine - Google Patents

Muundatud vaktsiiniaviirus Ankara (MVA), sellega nakatatud peremeesrakk ning seda sisaldav farmatseutiline kompositsioon, MVA valmistamine ja raviotstarbeline kasutamine

Info

Publication number
EE200200507A
EE200200507A EEP200200507A EEP200200507A EE200200507A EE 200200507 A EE200200507 A EE 200200507A EE P200200507 A EEP200200507 A EE P200200507A EE P200200507 A EEP200200507 A EE P200200507A EE 200200507 A EE200200507 A EE 200200507A
Authority
EE
Estonia
Prior art keywords
mva
preparation
virus ankara
pharmaceutical composition
host cell
Prior art date
Application number
EEP200200507A
Other languages
English (en)
Inventor
Mayr Anton
Original Assignee
Mayr Anton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayr Anton filed Critical Mayr Anton
Publication of EE200200507A publication Critical patent/EE200200507A/et
Publication of EE05633B1 publication Critical patent/EE05633B1/et

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • C12N7/08Inactivation or attenuation by serial passage of virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/12Viral antigens
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    • A61K39/285Vaccinia virus or variola virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24132Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
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    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
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    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24161Methods of inactivation or attenuation

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  • Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EEP200200507A 2000-03-14 2001-03-10 Muundatud vaktsiiniaviirus Ankara (MVA), sellega nakatatud peremeesrakk ning seda sisaldav farmatseutiline kompositsioon, MVA valmistamine ja raviotstarbeline kasutamine EE05633B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000410 2000-03-14
PCT/EP2001/002703 WO2001068820A1 (en) 2000-03-14 2001-03-10 Altered strain of the modified vaccinia virus ankara (mva)

Publications (2)

Publication Number Publication Date
EE200200507A true EE200200507A (et) 2004-02-16
EE05633B1 EE05633B1 (et) 2013-02-15

Family

ID=8159327

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200507A EE05633B1 (et) 2000-03-14 2001-03-10 Muundatud vaktsiiniaviirus Ankara (MVA), sellega nakatatud peremeesrakk ning seda sisaldav farmatseutiline kompositsioon, MVA valmistamine ja raviotstarbeline kasutamine

Country Status (25)

Country Link
US (1) US6682743B2 (et)
EP (1) EP1263936B1 (et)
JP (1) JP4759201B2 (et)
KR (1) KR100880765B1 (et)
CN (1) CN1291012C (et)
AT (1) ATE305030T1 (et)
AU (1) AU780696B2 (et)
BR (1) BR0109158A (et)
CA (1) CA2397675C (et)
CZ (1) CZ293690B6 (et)
DE (1) DE60113512T2 (et)
DK (1) DK1263936T3 (et)
EE (1) EE05633B1 (et)
ES (1) ES2249430T3 (et)
HK (1) HK1052725B (et)
HU (1) HU228691B1 (et)
IL (3) IL150736A0 (et)
MX (1) MXPA02008873A (et)
NO (1) NO20024246D0 (et)
NZ (1) NZ521270A (et)
PL (1) PL205922B1 (et)
RU (1) RU2280075C2 (et)
SI (1) SI1263936T1 (et)
UA (1) UA84388C2 (et)
WO (1) WO2001068820A1 (et)

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US7628980B2 (en) 2000-11-23 2009-12-08 Bavarian Nordic A/S Modified vaccinia virus ankara for the vaccination of neonates
US7445924B2 (en) 2000-11-23 2008-11-04 Bavarian Nordic A/S Modified Vaccinia Ankara virus variant and cultivation method
EP1357127A1 (de) * 2002-04-10 2003-10-29 Immusystems GmbH CD4+ T-Lymphozyten spezifische Hepatitis C Virus-Epitope
IL163701A0 (en) * 2002-04-19 2005-12-18 Bavarian Nordic As Modified vaccinia virus ankara for the vaccinationof neonates
SI1407033T1 (sl) * 2002-05-16 2006-06-30 Bavarian Nordic As Intergenske regije kot insercijska mesta v genomumodificiranega virusavakcinije Ankara (MVA)
US7501127B2 (en) 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
EP1434858B2 (en) * 2002-09-05 2018-12-19 Bavarian Nordic A/S Method for the amplification of a poxvirus under serum free conditions
EP1601333B1 (en) 2003-02-20 2013-01-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Novel insertion sites in pox vectors
EP1518932A1 (en) * 2003-09-29 2005-03-30 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Modified vaccinia virus Ankara (MVA) mutant and use thereof
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DK1845164T3 (da) * 2003-11-24 2010-09-20 Bavarian Nordic As Promoterer til ekspression i modificeret vacciniavirus ankara
DE102004003572A1 (de) * 2004-01-23 2005-08-18 Bavarian Nordic A/S Monoparamunitätsinducer basierend auf attenuierten Myxomaviren des Kaninchens
WO2006113927A2 (en) * 2005-04-20 2006-10-26 University Of Washington Immunogenic vaccinia peptides and methods of using same
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IL188667A (en) 2011-09-27
IL150736A0 (en) 2003-02-12
US20030013190A1 (en) 2003-01-16
PL205922B1 (pl) 2010-06-30
AU5826901A (en) 2001-09-24
WO2001068820A1 (en) 2001-09-20
SI1263936T1 (sl) 2006-06-30
NO20024246L (no) 2002-09-05
ATE305030T1 (de) 2005-10-15
RU2280075C2 (ru) 2006-07-20
NO20024246D0 (no) 2002-09-05
EE05633B1 (et) 2013-02-15
AU780696B2 (en) 2005-04-14
KR20030032928A (ko) 2003-04-26
KR100880765B1 (ko) 2009-02-02
JP2003526362A (ja) 2003-09-09
NZ521270A (en) 2003-06-30
DE60113512D1 (de) 2006-02-02
EP1263936A1 (en) 2002-12-11
US6682743B2 (en) 2004-01-27
CA2397675A1 (en) 2001-09-20
CN1418248A (zh) 2003-05-14
ES2249430T3 (es) 2006-04-01
IL150736A (en) 2008-06-05
HU228691B1 (en) 2013-05-28
BR0109158A (pt) 2003-04-22
HK1052725A1 (en) 2003-09-26
HUP0300120A3 (en) 2010-01-28
HUP0300120A2 (en) 2003-05-28
RU2002124622A (ru) 2004-03-27
CZ293690B6 (cs) 2004-07-14
MXPA02008873A (es) 2003-02-10
IL188667A0 (en) 2008-04-13
PL357378A1 (en) 2004-07-26
CN1291012C (zh) 2006-12-20
DK1263936T3 (da) 2006-02-13
DE60113512T2 (de) 2006-06-22
HK1052725B (zh) 2007-03-23
EP1263936B1 (en) 2005-09-21
JP4759201B2 (ja) 2011-08-31
CA2397675C (en) 2012-11-13
UA84388C2 (ru) 2008-10-27

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