EE200100659A - Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks - Google Patents

Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks

Info

Publication number: EE200100659A
Authority: EE; Estonia
Prior art keywords: diaminothiazoles; inhibition; protein kinases; kinases; protein
Prior art date: 1999-06-04

Application number

EEP200100659A

Other languages

English (en)

Estonian (et)

Inventor

Song Chu Shao

Andrew Alegria Larry

Lee Bender Steven

Pritchett Benedict Suzanne

J. Borchardt Allen

Steven Kania Robert

David Nambu Mitchell

Maria Tempczyk-Russell Anna

Sarshar Sepehr

Bhumralkar Dilip

Peng Zhengwei

Michelle Yang Yi

Original Assignee

Agouron Pharmaceuticals, Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-04

Filing date

2000-06-02

Publication date

2003-02-17

2000-06-02 Application filed by Agouron Pharmaceuticals, Inc. filed Critical Agouron Pharmaceuticals, Inc.

2003-02-17 Publication of EE200100659A publication Critical patent/EE200100659A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms
- C07F9/6539—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

EEP200100659A 1999-06-04 2000-06-02 Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks EE200100659A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13781099P	1999-06-04	1999-06-04
PCT/US2000/015188 WO2000075120A1 (en)	1999-06-04	2000-06-02	Diaminothiazoles and their use for inhibiting protein kinases

Publications (1)

Publication Number	Publication Date
EE200100659A true EE200100659A (et)	2003-02-17

Family

ID=22479135

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100659A EE200100659A (et)	1999-06-04	2000-06-02	Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks

Country Status (34)

Country	Link
US (1)	US6620828B2 (xx)
EP (1)	EP1181283B1 (xx)
JP (1)	JP2003501420A (xx)
KR (1)	KR20020015333A (xx)
CN (1)	CN1359380A (xx)
AP (1)	AP2001002341A0 (xx)
AT (1)	ATE288424T1 (xx)
AU (1)	AU778071B2 (xx)
BG (1)	BG106276A (xx)
BR (1)	BR0011585A (xx)
CA (1)	CA2371158A1 (xx)
CZ (1)	CZ20014213A3 (xx)
DE (1)	DE60017894T2 (xx)
EA (1)	EA200101268A1 (xx)
EE (1)	EE200100659A (xx)
ES (1)	ES2234628T3 (xx)
HR (1)	HRP20020008A2 (xx)
HU (1)	HUP0202897A3 (xx)
IL (1)	IL146094A0 (xx)
IS (1)	IS6183A (xx)
MA (1)	MA25530A1 (xx)
MX (1)	MXPA01012483A (xx)
NO (1)	NO20015045L (xx)
NZ (1)	NZ514881A (xx)
OA (1)	OA11959A (xx)
PE (1)	PE20010211A1 (xx)
PL (1)	PL352714A1 (xx)
SK (1)	SK17302001A3 (xx)
SV (1)	SV2002000096A (xx)
UA (1)	UA71971C2 (xx)
UY (1)	UY26190A1 (xx)
WO (1)	WO2000075120A1 (xx)
YU (1)	YU85601A (xx)
ZA (1)	ZA200108291B (xx)

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ATE288904T1 (de) *	1998-06-18	2005-02-15	Bristol Myers Squibb Co	Durch kohlenstoff substituierte aminothiazole als inhibitoren von zyclin-abhägigen kinasen
WO2000018761A1 (en)	1998-09-29	2000-04-06	American Cyanamid Company	Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors

2000
- 2000-02-06 UA UA2001129215A patent/UA71971C2/uk unknown
- 2000-06-02 PL PL00352714A patent/PL352714A1/xx not_active Application Discontinuation
- 2000-06-02 CN CN00808440A patent/CN1359380A/zh active Pending
- 2000-06-02 SV SV2000000096A patent/SV2002000096A/es unknown
- 2000-06-02 AU AU57254/00A patent/AU778071B2/en not_active Ceased
- 2000-06-02 AP APAP/P/2001/002341A patent/AP2001002341A0/en unknown
- 2000-06-02 IL IL14609400A patent/IL146094A0/xx unknown
- 2000-06-02 CA CA002371158A patent/CA2371158A1/en not_active Abandoned
- 2000-06-02 EA EA200101268A patent/EA200101268A1/ru unknown
- 2000-06-02 SK SK1730-2001A patent/SK17302001A3/sk unknown
- 2000-06-02 BR BR0011585-1A patent/BR0011585A/pt not_active IP Right Cessation
- 2000-06-02 YU YU85601A patent/YU85601A/sh unknown
- 2000-06-02 KR KR1020017015384A patent/KR20020015333A/ko not_active Withdrawn
- 2000-06-02 HU HU0202897A patent/HUP0202897A3/hu unknown
- 2000-06-02 OA OA1200100321A patent/OA11959A/en unknown
- 2000-06-02 CZ CZ20014213A patent/CZ20014213A3/cs unknown
- 2000-06-02 ES ES00942660T patent/ES2234628T3/es not_active Expired - Lifetime
- 2000-06-02 MX MXPA01012483A patent/MXPA01012483A/es not_active Application Discontinuation
- 2000-06-02 PE PE2000000553A patent/PE20010211A1/es not_active Application Discontinuation
- 2000-06-02 NZ NZ514881A patent/NZ514881A/en unknown
- 2000-06-02 AT AT00942660T patent/ATE288424T1/de not_active IP Right Cessation
- 2000-06-02 HR HR20020008A patent/HRP20020008A2/hr not_active Application Discontinuation
- 2000-06-02 UY UY26190A patent/UY26190A1/es not_active Application Discontinuation
- 2000-06-02 DE DE60017894T patent/DE60017894T2/de not_active Expired - Fee Related
- 2000-06-02 WO PCT/US2000/015188 patent/WO2000075120A1/en not_active Ceased
- 2000-06-02 EP EP00942660A patent/EP1181283B1/en not_active Expired - Lifetime
- 2000-06-02 EE EEP200100659A patent/EE200100659A/xx unknown
- 2000-06-02 JP JP2001501601A patent/JP2003501420A/ja not_active Abandoned
2001
- 2001-02-15 US US09/783,584 patent/US6620828B2/en not_active Expired - Fee Related
- 2001-10-09 ZA ZA200108291A patent/ZA200108291B/xx unknown
- 2001-10-17 NO NO20015045A patent/NO20015045L/no not_active Application Discontinuation
- 2001-11-29 IS IS6183A patent/IS6183A/is unknown
2002
- 2002-01-02 MA MA26465A patent/MA25530A1/fr unknown
- 2002-01-03 BG BG106276A patent/BG106276A/bg unknown

Also Published As

Publication number	Publication date
ES2234628T3 (es)	2005-07-01
EP1181283A1 (en)	2002-02-27
EA200101268A1 (ru)	2002-06-27
NZ514881A (en)	2003-10-31
BG106276A (bg)	2002-10-31
EP1181283B1 (en)	2005-02-02
DE60017894T2 (de)	2005-12-29
AP2001002341A0 (en)	2001-12-31
HRP20020008A2 (en)	2004-02-29
NO20015045D0 (no)	2001-10-17
ATE288424T1 (de)	2005-02-15
OA11959A (en)	2006-04-17
PL352714A1 (en)	2003-09-08
HUP0202897A2 (hu)	2002-12-28
UY26190A1 (es)	2000-12-29
US6620828B2 (en)	2003-09-16
ZA200108291B (en)	2002-12-24
IL146094A0 (en)	2002-07-25
KR20020015333A (ko)	2002-02-27
PE20010211A1 (es)	2001-03-16
IS6183A (is)	2001-11-29
SV2002000096A (es)	2002-06-07
NO20015045L (no)	2002-02-04
SK17302001A3 (sk)	2004-01-08
CA2371158A1 (en)	2000-12-14
AU778071B2 (en)	2004-11-11
WO2000075120A1 (en)	2000-12-14
MA25530A1 (fr)	2002-10-01
DE60017894D1 (de)	2005-03-10
MXPA01012483A (es)	2002-07-30
AU5725400A (en)	2000-12-28
BR0011585A (pt)	2002-03-19
UA71971C2 (en)	2005-01-17
US20020025976A1 (en)	2002-02-28
CN1359380A (zh)	2002-07-17
HUP0202897A3 (en)	2004-12-28
CZ20014213A3 (cs)	2002-04-17
YU85601A (sh)	2004-09-03
JP2003501420A (ja)	2003-01-14

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