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EE200000473A - E-2-[4-(4-kloro-1,2-difenüül-but-1-enüül)fenoksü]etanool ja selle farmatseutilised koostised - Google Patents

E-2-[4-(4-kloro-1,2-difenüül-but-1-enüül)fenoksü]etanool ja selle farmatseutilised koostised

Info

Publication number
EE200000473A
EE200000473A EEP200000473A EEP200000473A EE200000473A EE 200000473 A EE200000473 A EE 200000473A EE P200000473 A EEP200000473 A EE P200000473A EE P200000473 A EEP200000473 A EE P200000473A EE 200000473 A EE200000473 A EE 200000473A
Authority
EE
Estonia
Prior art keywords
enyl
phenoxy
diphenyl
chloro
ethanol
Prior art date
Application number
EEP200000473A
Other languages
English (en)
Inventor
Marketta Kalapudas Arja
S�dervall Marja-Liisa
Viitanen Antti
M�ntyl� Eero
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of EE200000473A publication Critical patent/EE200000473A/et
Publication of EE04233B1 publication Critical patent/EE04233B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200000473A 1998-02-19 1999-02-19 E-2-[4-(4-kloro-1,2-difenüül-but-1-enüül)fenoksü]etanool ja selle farmatseutilised koostised EE04233B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9803521.5A GB9803521D0 (en) 1998-02-19 1998-02-19 New compounds and pharmaceutical compositions thereof
PCT/FI1999/000137 WO1999042427A1 (en) 1998-02-19 1999-02-19 E-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol and pharmaceutical compositions thereof

Publications (2)

Publication Number Publication Date
EE200000473A true EE200000473A (et) 2001-12-17
EE04233B1 EE04233B1 (et) 2004-02-16

Family

ID=10827263

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000473A EE04233B1 (et) 1998-02-19 1999-02-19 E-2-[4-(4-kloro-1,2-difenüül-but-1-enüül)fenoksü]etanool ja selle farmatseutilised koostised

Country Status (33)

Country Link
US (1) US6395785B1 (et)
EP (1) EP1056701B1 (et)
JP (1) JP2002503713A (et)
KR (1) KR100755918B1 (et)
CN (1) CN1161314C (et)
AR (1) AR014961A1 (et)
AT (1) ATE252531T1 (et)
AU (1) AU755798B2 (et)
BG (1) BG64471B1 (et)
BR (1) BR9907688A (et)
CA (1) CA2321122C (et)
CZ (1) CZ294315B6 (et)
DE (1) DE69912247T2 (et)
DK (1) DK1056701T3 (et)
EA (1) EA002919B1 (et)
EE (1) EE04233B1 (et)
ES (1) ES2211038T3 (et)
GB (1) GB9803521D0 (et)
GE (1) GEP20022794B (et)
HR (1) HRP20000545A2 (et)
HU (1) HUP0101354A3 (et)
ID (1) ID26857A (et)
IL (1) IL137214A (et)
NO (1) NO325595B1 (et)
NZ (1) NZ505637A (et)
PL (1) PL193315B1 (et)
PT (1) PT1056701E (et)
RS (1) RS49660B (et)
SK (1) SK285940B6 (et)
TR (1) TR200002037T2 (et)
UA (1) UA57132C2 (et)
WO (1) WO1999042427A1 (et)
ZA (1) ZA991232B (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1705169A3 (en) * 1999-11-16 2006-11-15 Hormos Medical Ltd. Triphenylalkene derivatives and their use as selective estrogen receptor modulators
TW593256B (en) 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
JP5123935B2 (ja) 2006-05-22 2013-01-23 ホルモス メディカル リミテッド 選択的エストロゲン受容体モジュレーターまたはアロマターゼ阻害剤を用いた慢性非細菌性前立腺炎の治療方法
WO2008099060A2 (en) 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
BRPI0807675B1 (pt) 2007-02-14 2021-05-18 Hormos Medical Ltd. método para a preparação de um composto derivado de trifenilbuteno
DK2526080T3 (da) 2010-01-19 2014-04-28 Cambrex Karlskoga Ab Nye fremgangsmåder til fremstilling af benzophenonderivater
US9321712B2 (en) 2012-10-19 2016-04-26 Fermion Oy Process for the preparation of ospemifene
WO2014060640A1 (en) * 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CN104030896A (zh) * 2013-03-07 2014-09-10 天津药物研究院 一种简易去除欧司哌米芬特异杂质的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2126576B (en) 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
GB9604577D0 (en) * 1996-03-04 1996-05-01 Orion Yhtymae Oy Serum cholesterol lowering agent

Also Published As

Publication number Publication date
AU755798B2 (en) 2002-12-19
CZ20002927A3 (cs) 2000-12-13
ES2211038T3 (es) 2004-07-01
ZA991232B (en) 1999-09-17
SK285940B6 (sk) 2007-11-02
UA57132C2 (uk) 2003-06-16
US6395785B1 (en) 2002-05-28
NO325595B1 (no) 2008-06-23
KR100755918B1 (ko) 2007-09-06
BG104713A (bg) 2001-03-30
DK1056701T3 (da) 2004-02-02
CN1291178A (zh) 2001-04-11
AU2524499A (en) 1999-09-06
GB9803521D0 (en) 1998-04-15
DE69912247D1 (de) 2003-11-27
HUP0101354A2 (hu) 2002-03-28
HUP0101354A3 (en) 2002-05-28
EE04233B1 (et) 2004-02-16
NO20003987L (no) 2000-08-07
JP2002503713A (ja) 2002-02-05
WO1999042427A1 (en) 1999-08-26
PT1056701E (pt) 2004-03-31
EP1056701B1 (en) 2003-10-22
SK12052000A3 (sk) 2001-01-18
IL137214A0 (en) 2001-07-24
EP1056701A1 (en) 2000-12-06
CA2321122A1 (en) 1999-08-26
ATE252531T1 (de) 2003-11-15
HRP20000545A2 (en) 2001-02-28
CN1161314C (zh) 2004-08-11
ID26857A (id) 2001-02-15
KR20010040985A (ko) 2001-05-15
EA200000851A1 (ru) 2001-02-26
GEP20022794B (en) 2002-09-25
PL342445A1 (en) 2001-06-04
IL137214A (en) 2005-05-17
CA2321122C (en) 2008-02-12
BG64471B1 (bg) 2005-04-30
AR014961A1 (es) 2001-04-11
DE69912247T2 (de) 2004-07-29
PL193315B1 (pl) 2007-01-31
CZ294315B6 (cs) 2004-11-10
NO20003987D0 (no) 2000-08-07
EA002919B1 (ru) 2002-10-31
NZ505637A (en) 2002-10-25
TR200002037T2 (tr) 2001-02-21
YU51000A (sh) 2002-11-15
RS49660B (sr) 2007-09-21
BR9907688A (pt) 2000-11-14

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

GB1A Change in the ownership or in the address of the owner
KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

MM4A Lapsed by not paying the annual fees

Effective date: 20090219