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EE200000356A - DNA molekul, mis kodeerib mutantset prepro-neuropeptiidi Y, mutantne signaalpeptiid ja nende kasutamine - Google Patents

DNA molekul, mis kodeerib mutantset prepro-neuropeptiidi Y, mutantne signaalpeptiid ja nende kasutamine

Info

Publication number
EE200000356A
EE200000356A EEP200000356A EEP200000356A EE200000356A EE 200000356 A EE200000356 A EE 200000356A EE P200000356 A EEP200000356 A EE P200000356A EE P200000356 A EEP200000356 A EE P200000356A EE 200000356 A EE200000356 A EE 200000356A
Authority
EE
Estonia
Prior art keywords
mutant
neuropeptide
signal peptide
dna molecule
molecule encoding
Prior art date
Application number
EEP200000356A
Other languages
English (en)
Inventor
Koulu Markku
Karvonen Matti
Pesonen Ullamari
Uusitupa Matti
Original Assignee
Hormos Medical Oy Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hormos Medical Oy Ltd. filed Critical Hormos Medical Oy Ltd.
Publication of EE200000356A publication Critical patent/EE200000356A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57545—Neuropeptide Y
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EEP200000356A 1997-12-19 1998-12-16 DNA molekul, mis kodeerib mutantset prepro-neuropeptiidi Y, mutantne signaalpeptiid ja nende kasutamine EE200000356A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/994,946 US6046317A (en) 1997-12-19 1997-12-19 DNA molecule encoding a mutant prepro-neuropeptide Y, a mutant signal peptide, and uses thereof
PCT/FI1998/000985 WO1999032518A1 (en) 1997-12-19 1998-12-16 A dna molecule encoding a mutant prepro-neuropeptide y, a mutant signal peptide, and uses thereof

Publications (1)

Publication Number Publication Date
EE200000356A true EE200000356A (et) 2001-10-15

Family

ID=25541250

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000356A EE200000356A (et) 1997-12-19 1998-12-16 DNA molekul, mis kodeerib mutantset prepro-neuropeptiidi Y, mutantne signaalpeptiid ja nende kasutamine

Country Status (15)

Country Link
US (2) US6046317A (et)
EP (1) EP1037922A1 (et)
JP (1) JP2001526296A (et)
KR (1) KR20010033351A (et)
CN (1) CN1211486C (et)
AU (1) AU752138B2 (et)
BR (1) BR9813813A (et)
CA (1) CA2314614A1 (et)
EE (1) EE200000356A (et)
HU (1) HUP0100674A3 (et)
NO (1) NO20003116L (et)
NZ (2) NZ504633A (et)
PL (1) PL195844B1 (et)
RU (1) RU2219186C2 (et)
WO (1) WO1999032518A1 (et)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL362862A1 (en) * 2000-03-21 2004-11-02 Hormos Medical Corporation Diagnosis of a person's risk of developing alcoholism
WO2002015941A1 (en) * 2000-08-25 2002-02-28 Hormos Medical Corporation A method for reducing stress-induced overproduction of neuropeptide y in an individual
US7054758B2 (en) * 2001-01-30 2006-05-30 Sciona Limited Computer-assisted means for assessing lifestyle risk factors
AU2002315165A1 (en) * 2001-06-14 2003-01-02 Genelink, Inc. Kits and methods for assessing leptin-mediated lipid matabolism
US20040254131A1 (en) * 2003-06-16 2004-12-16 Markku Koulu Method for prevention or treatment of diseases or disorders related to excessive formation of vascular tissue or blood vessels
US20090213731A1 (en) * 2005-04-15 2009-08-27 Regenertech Pty Limited Use of neuropeptide y (npy) and agonists and antagonists thereof for tissue regeneration

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455164A (en) * 1989-11-03 1995-10-03 Mcgill University Ruminant immortalized mammary epithelial cell lines
GB9406974D0 (en) * 1994-04-08 1994-06-01 Pharmaceutical Proteins Ltd Transgenic production
GB9708918D0 (en) * 1997-05-01 1997-06-25 Ppl Therapeutics Scotland Ltd Methods

Also Published As

Publication number Publication date
EP1037922A1 (en) 2000-09-27
CN1282338A (zh) 2001-01-31
NZ514067A (en) 2001-09-28
WO1999032518A1 (en) 1999-07-01
US6046317A (en) 2000-04-04
CN1211486C (zh) 2005-07-20
BR9813813A (pt) 2001-09-25
KR20010033351A (ko) 2001-04-25
AU1673599A (en) 1999-07-12
US20030093821A1 (en) 2003-05-15
HUP0100674A3 (en) 2004-10-28
JP2001526296A (ja) 2001-12-18
PL195844B1 (pl) 2007-10-31
CA2314614A1 (en) 1999-07-01
HUP0100674A2 (hu) 2001-06-28
US7084242B2 (en) 2006-08-01
PL341362A1 (en) 2001-04-09
NO20003116L (no) 2000-08-18
NO20003116D0 (no) 2000-06-16
AU752138B2 (en) 2002-09-05
RU2219186C2 (ru) 2003-12-20
NZ504633A (en) 2002-11-26

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