EE200000020A - 2,4,4-triasendatud-1,3-dioksolaanid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, kombinatsioon ja produkt - Google Patents

2,4,4-triasendatud-1,3-dioksolaanid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, kombinatsioon ja produkt

Info

Publication number: EE200000020A
Authority: EE; Estonia
Prior art keywords: dioxolanes; trisubstituted; preparation; combination; product
Prior art date: 1997-07-11

Application number

EEP200000020A

Other languages

English (en)

Inventor

Christopher Odds Frank

Florent Adolf Vanden Bossche Hugo

Jozef Elisabeth Van Der Veken Louis

Meerpoel Lieven

Heeres Jan

Original Assignee

Janssen Pharmaceutica N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-11

Filing date

1998-07-07

Publication date

2000-10-16

1998-07-07 Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.

2000-10-16 Publication of EE200000020A publication Critical patent/EE200000020A/et

2003-10-15 Publication of EE04155B1 publication Critical patent/EE04155B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

EEP200000020A 1997-07-11 1998-07-07 2,4,4-triasendatud-1,3-dioksolaanid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, kombinatsioon ja produkt EE04155B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97202181		1997-07-11
PCT/EP1998/004194 WO1999002523A1 (en)	1997-07-11	1998-07-07	2,4,4-trisubstituted-1,3-dioxolane antifungals

Publications (2)

Publication Number	Publication Date
EE200000020A true EE200000020A (et)	2000-10-16
EE04155B1 EE04155B1 (et)	2003-10-15

Family

ID=8228553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000020A EE04155B1 (et)	1997-07-11	1998-07-07	2,4,4-triasendatud-1,3-dioksolaanid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, kombinatsioon ja produkt

Country Status (33)

Country	Link
US (1)	US6387906B1 (et)
EP (1)	EP1068200B1 (et)
KR (1)	KR100540460B1 (et)
AP (1)	AP1379A (et)
AR (1)	AR015130A1 (et)
AT (1)	ATE289303T1 (et)
AU (1)	AU749760B2 (et)
BG (1)	BG64314B1 (et)
BR (1)	BRPI9811679B8 (et)
CA (1)	CA2295090C (et)
CZ (1)	CZ297453B6 (et)
DE (1)	DE69829082T2 (et)
DK (1)	DK1068200T3 (et)
EA (1)	EA002828B1 (et)
EE (1)	EE04155B1 (et)
ES (1)	ES2238765T3 (et)
GE (1)	GEP20033054B (et)
HR (1)	HRP20000007B1 (et)
HU (1)	HU225159B1 (et)
ID (1)	ID23783A (et)
IL (1)	IL133919A (et)
MY (1)	MY118844A (et)
NO (1)	NO318328B1 (et)
NZ (1)	NZ501982A (et)
PL (1)	PL193703B1 (et)
PT (1)	PT1068200E (et)
SI (1)	SI1068200T1 (et)
SK (1)	SK285321B6 (et)
TR (1)	TR200000154T2 (et)
TW (1)	TW593312B (et)
UA (1)	UA71543C2 (et)
WO (1)	WO1999002523A1 (et)
ZA (1)	ZA986160B (et)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19945982A1 (de) *	1999-09-24	2001-03-29	Knoll Ag	Geschwindigkeitsbestimmte Partikel
US20040086567A1 (en) *	2002-10-30	2004-05-06	Pawan Seth	Bioequivalent composition of itraconazole and a hydrophilic polymer
CN102015582A (zh) *	2008-03-03	2011-04-13	施泰福实验室股份有限公司	光学纯二元醇和二氧戊环化合物的制备方法
US8431699B2 (en) *	2009-02-27	2013-04-30	Vertichem Corporation	Method for manufacture of 2-oxoimidazolidines
CN105777486B (zh) *	2016-03-30	2018-09-11	浙江大学宁波理工学院	一种2-[2-(2，4-二氟苯基)-2-丙烯-1-基]-1，3-丙二醇的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4218458A (en) *	1978-06-23	1980-08-19	Janssen Pharmaceutica, N.V.	Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4619931A (en) *	1983-02-28	1986-10-28	Janssen Pharmaceutica, N.V.	[[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles
CA1292472C (en) *	1985-12-03	1991-11-26	Alfonsus Guilielmus Knaeps	Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl\|-1,3-dioxolan-2-yl\|methyl\|-1h-imidazoles and 1h-1,2,4-triazoles
US4788190A (en) *	1986-12-24	1988-11-29	Schering Corporation	2,4,4-tri- and 2,2,4,4-tetra substituted-1,3-dioxolane antifungal, antiallergy compounds
NZ233502A (en) *	1989-06-09	1991-11-26	Janssen Pharmaceutica Nv	4-(1,2,4-triazole- or imidazole-phenyl-substituted) -1-(1,3-dioxolan-4-ylmethoxyphenyl) piperazine derivatives; preparatory processes: fungicidal and antiviral compositions
IL103558A0 (en)	1991-10-30	1993-03-15	Schering Corp	Tri-substituted tetrahydrofuran antifungals
DK0741737T3 (da) *	1994-01-24	2000-05-22	Janssen Pharmaceutica Nv	Vandopløslige antifugale azoler

1998
- 1998-07-06 TW TW087110868A patent/TW593312B/zh not_active IP Right Cessation
- 1998-07-07 HR HR20000007A patent/HRP20000007B1/xx not_active IP Right Cessation
- 1998-07-07 US US09/462,588 patent/US6387906B1/en not_active Expired - Lifetime
- 1998-07-07 MY MYPI98003075A patent/MY118844A/en unknown
- 1998-07-07 ES ES98940160T patent/ES2238765T3/es not_active Expired - Lifetime
- 1998-07-07 CA CA002295090A patent/CA2295090C/en not_active Expired - Lifetime
- 1998-07-07 DE DE69829082T patent/DE69829082T2/de not_active Expired - Lifetime
- 1998-07-07 HU HU0004459A patent/HU225159B1/hu unknown
- 1998-07-07 UA UA2000010162A patent/UA71543C2/uk unknown
- 1998-07-07 CZ CZ0463799A patent/CZ297453B6/cs not_active IP Right Cessation
- 1998-07-07 TR TR2000/00154T patent/TR200000154T2/xx unknown
- 1998-07-07 GE GEAP19985200A patent/GEP20033054B/en unknown
- 1998-07-07 EP EP98940160A patent/EP1068200B1/en not_active Expired - Lifetime
- 1998-07-07 AP APAP/P/2000/001730A patent/AP1379A/en active
- 1998-07-07 DK DK98940160T patent/DK1068200T3/da active
- 1998-07-07 AT AT98940160T patent/ATE289303T1/de active
- 1998-07-07 WO PCT/EP1998/004194 patent/WO1999002523A1/en not_active Ceased
- 1998-07-07 AU AU88576/98A patent/AU749760B2/en not_active Expired
- 1998-07-07 IL IL13391998A patent/IL133919A/en not_active IP Right Cessation
- 1998-07-07 PT PT98940160T patent/PT1068200E/pt unknown
- 1998-07-07 PL PL98338009A patent/PL193703B1/pl unknown
- 1998-07-07 ID IDW20000032A patent/ID23783A/id unknown
- 1998-07-07 KR KR1019997012503A patent/KR100540460B1/ko not_active Expired - Lifetime
- 1998-07-07 SI SI9830764T patent/SI1068200T1/xx unknown
- 1998-07-07 SK SK1841-99A patent/SK285321B6/sk not_active IP Right Cessation
- 1998-07-07 NZ NZ501982A patent/NZ501982A/xx not_active IP Right Cessation
- 1998-07-07 EA EA200000116A patent/EA002828B1/ru not_active IP Right Cessation
- 1998-07-07 EE EEP200000020A patent/EE04155B1/et unknown
- 1998-07-07 BR BRPI9811679A patent/BRPI9811679B8/pt not_active IP Right Cessation
- 1998-07-10 ZA ZA9806160A patent/ZA986160B/xx unknown
- 1998-07-10 AR ARP980103376A patent/AR015130A1/es active IP Right Grant
1999
- 1999-12-10 BG BG103982A patent/BG64314B1/bg unknown
2000
- 2000-01-10 NO NO20000114A patent/NO318328B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1999002523A1 (en)	1999-01-21
TR200000154T2 (tr)	2000-06-21
SI1068200T1 (et)	2005-08-31
NO20000114D0 (no)	2000-01-10
GEP20033054B (en)	2003-08-25
UA71543C2 (uk)	2004-12-15
CZ297453B6 (cs)	2006-12-13
ES2238765T3 (es)	2005-09-01
HRP20000007A2 (en)	2000-12-31
ID23783A (id)	2000-05-11
NO20000114L (no)	2000-03-13
ZA986160B (en)	2000-01-10
HK1032404A1 (en)	2001-07-20
IL133919A0 (en)	2001-04-30
CZ463799A3 (cs)	2000-04-12
CA2295090C (en)	2009-09-08
AR015130A1 (es)	2001-04-18
PL193703B1 (pl)	2007-03-30
BRPI9811679B8 (pt)	2021-05-25
HU225159B1 (en)	2006-07-28
BG64314B1 (bg)	2004-09-30
HUP0004459A3 (en)	2002-11-28
EE04155B1 (et)	2003-10-15
AP1379A (en)	2005-03-29
AU8857698A (en)	1999-02-08
HRP20000007B1 (en)	2008-12-31
EP1068200A1 (en)	2001-01-17
EA002828B1 (ru)	2002-10-31
PL338009A1 (en)	2000-09-25
ATE289303T1 (de)	2005-03-15
NO318328B1 (no)	2005-03-07
HUP0004459A2 (hu)	2002-04-29
EP1068200B1 (en)	2005-02-16
SK184199A3 (en)	2000-07-11
SK285321B6 (sk)	2006-11-03
CA2295090A1 (en)	1999-01-21
DK1068200T3 (da)	2005-06-20
DE69829082T2 (de)	2005-12-29
BRPI9811679B1 (pt)	2016-10-18
BR9811679A (pt)	2000-09-19
PT1068200E (pt)	2005-07-29
AU749760B2 (en)	2002-07-04
IL133919A (en)	2002-02-10
EA200000116A1 (ru)	2000-08-28
US6387906B1 (en)	2002-05-14
KR20010020576A (ko)	2001-03-15
TW593312B (en)	2004-06-21
MY118844A (en)	2005-01-31
DE69829082D1 (de)	2005-03-24
NZ501982A (en)	2000-10-27
KR100540460B1 (ko)	2006-01-12
AP2000001730A0 (en)	2000-03-31
BG103982A (en)	2000-08-31

Publication	Publication Date	Title
EE200100252A (et)	2002-10-15	Pürimidiinderivaadid, nende valmistamismeetod ja kasutamine, farmatseutiline kompositsioon ja sellevalmistamismeetod, kombinatsioon ning saadus
FI973039A0 (fi)	1997-07-17	Uusia farnesyylitransferaasin inhibiittoreita, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia
FI973279A0 (fi)	1997-08-08	Uudet farnesyylitransferaasin inhibiittorit, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset
EE9500064A (et)	1996-06-17	Asendatud 1H-imidasoolid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
NO953657D0 (no)	1995-09-15	Nytt farmasöytisk produkt
HUP0001508A3 (en)	2003-01-28	4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
HUP9900974A3 (en)	2000-09-28	Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them
HUP0102307A3 (en)	2002-02-28	Bispidine derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
FI953898L (fi)	1996-02-20	Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita
FI954612L (fi)	1996-03-30	Uusia imidatsolidiinejä, jotka on substituoitu heterosyklillä, niiden valmistusmenetelmä ja -välituotetteita, niiden käyttö lääkkeinä ja niitä sisältävät farmaseuttiset koostumukset
EE200000652A (et)	2002-04-15	Farmatseutiline kompositsioon ja produkt
EE9800302A (et)	1999-02-15	Arüülglütsiinamiidi derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline preparaat
FI952550A7 (fi)	1995-11-28	Uudet N-pyridyylikarboksamidit ja johdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE03825B1 (et)	2002-08-15	2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
FI943688L (fi)	1995-03-21	Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet
FI950625A7 (fi)	1995-08-15	Polysubstituoituja 3-asyyliamino-5-fenyyli-1,4-bentsodiatsepiini-2-onijohdannaisia, menetelmä niiden valmistamiseksi ja niitä sisältäviä farmaseuttisia koostumuksia
FI941836A7 (fi)	1994-10-23	3-deoksioligosakkaridit, menetelmiä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE9800200A (et)	1998-12-15	Bensoüülguanidiini derivaadid, nende valmistamismeetod, kasutamine ja farmatseutiline kompositsioon
EE200000226A (et)	2001-06-15	3,6-poolketaalid 9a-asaliidide klassist, nende valmistamismeetod ja farmatseutiline kompositsioon
HUP9802393A3 (en)	2000-01-28	Benzothiazolone derivatives, their use, pharmaceutical compositions containing them, process for the preparation thereof and intermediates
FI960316L (fi)	1996-03-22	Oksatiolaanit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE03996B1 (et)	2003-04-15	Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine
EE04398B1 (et)	2004-12-15	Asendatud 1,2,3,4,5,6-heksahüdro-2,6-metano-3-bensasotsiin-10-oolid, nende valmistamise meetod ja kasutamine ravimitena
FI951091A7 (fi)	1995-09-12	Uudet alkyyliaminoindaaniyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE200000020A (et)	2000-10-16	2,4,4-triasendatud-1,3-dioksolaanid, nende valmistamismeetod, kasutamine, farmatseutiline kompositsioon, kombinatsioon ja produkt

Legal Events

Date	Code	Title	Description
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231