EE05281B1 - Fenofibraadi ja koensüüm Q10 kombinatsioon endoteeli düsfunktsiooni ravimiseks - Google Patents

Fenofibraadi ja koensüüm Q10 kombinatsioon endoteeli düsfunktsiooni ravimiseks

Info

Publication number: EE05281B1
Authority: EE; Estonia
Prior art keywords: fenofibrate; coenzyme; treatment; combination; endothelial dysfunction
Prior art date: 2000-10-26

Application number

EEP200300165A

Other languages

English (en)

Inventor

Watts Gerald

Playford David

Original Assignee

Fournier Laboratories Ireland Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-26

Filing date

2001-10-23

Publication date

2010-04-15

2000-10-26 Priority claimed from AUPR1038A external-priority patent/AUPR103800A0/en

2001-02-28 Priority claimed from AUPR3424A external-priority patent/AUPR342401A0/en

2001-10-23 Application filed by Fournier Laboratories Ireland Limited filed Critical Fournier Laboratories Ireland Limited

2003-06-16 Publication of EE200300165A publication Critical patent/EE200300165A/et

2010-04-15 Publication of EE05281B1 publication Critical patent/EE05281B1/et

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Obesity (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Hospice & Palliative Care (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

EEP200300165A 2000-10-26 2001-10-23 Fenofibraadi ja koensüüm Q10 kombinatsioon endoteeli düsfunktsiooni ravimiseks EE05281B1 (et)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
AUPR1038A AUPR103800A0 (en)	2000-10-26	2000-10-26	Compositions for the treatment of endothelial dysfunction
AUPR3424A AUPR342401A0 (en)	2001-02-28	2001-02-28	Compositions for the treatment of endothelial dysfunction
PCT/EP2001/012425 WO2002034259A1 (en)	2000-10-26	2001-10-23	Combination of fenofibrate and coenzyme q10 for the treatment of endothelial dysfunction

Publications (2)

Publication Number	Publication Date
EE200300165A EE200300165A (et)	2003-06-16
EE05281B1 true EE05281B1 (et)	2010-04-15

Family

ID=25646491

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300165A EE05281B1 (et)	2000-10-26	2001-10-23	Fenofibraadi ja koensüüm Q10 kombinatsioon endoteeli düsfunktsiooni ravimiseks

Country Status (29)

Country	Link
US (1)	US7410983B2 (et)
EP (1)	EP1328266B1 (et)
JP (1)	JP4236464B2 (et)
KR (1)	KR100862129B1 (et)
CN (1)	CN1220488C (et)
AR (1)	AR035071A1 (et)
AT (1)	ATE316787T1 (et)
AU (1)	AU2176502A (et)
BG (1)	BG65979B1 (et)
BR (1)	BR0114701A (et)
CA (1)	CA2426625C (et)
CY (1)	CY1105007T1 (et)
CZ (1)	CZ301282B6 (et)
DE (1)	DE60117046T2 (et)
DK (1)	DK1328266T3 (et)
DZ (1)	DZ3442A1 (et)
EE (1)	EE05281B1 (et)
ES (1)	ES2257457T3 (et)
HU (1)	HUP0303566A3 (et)
IL (2)	IL155524A0 (et)
MA (1)	MA25847A1 (et)
MX (1)	MXPA03003733A (et)
NO (1)	NO332260B1 (et)
PL (1)	PL212952B1 (et)
PT (1)	PT1328266E (et)
RU (1)	RU2003111175A (et)
SK (1)	SK287992B6 (et)
TN (1)	TNSN01151A1 (et)
WO (1)	WO2002034259A1 (et)

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ATE360417T1 (de)	2001-07-11	2007-05-15	Boehringer Ingelheim Pharma	Methode zur behandlung von zytokinvermittelten erkrankungen
AU2003208238A1 (en) *	2002-03-11	2003-09-22	TAYLOR, , Carla	Use of ppar alpha agonists for the treatment of vascular and renal diseases
US20070225614A1 (en)	2004-05-26	2007-09-27	Endothelix, Inc.	Method and apparatus for determining vascular health conditions
FR2845602B1 (fr) *	2002-10-11	2005-07-08	Servier Lab	Association entre un ligand des recepteurs actives par les proliferateurs de peroxisomes et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
GB0309154D0 (en)	2003-01-14	2003-05-28	Aventis Pharma Inc	Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia
JP2005104951A (ja) *	2003-01-17	2005-04-21	Kirin Brewery Co Ltd	血圧降下用組成物および血管柔軟性改善用組成物並びにこれらの機能が付与された食品
FR2868313B1 (fr) *	2004-03-31	2008-08-15	Servier Lab	Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent
EP1621200A1 (en) *	2004-07-26	2006-02-01	Fournier Laboratories Ireland Limited	Pharmaceutical combinations containing an inhibitor of platelet aggregation and a fibrate
JP2008542389A (ja)	2005-06-01	2008-11-27	エジソンファーマシューティカルズ，インコーポレイテッド	ミトコンドリア病および他の状態の治療、およびエネルギーバイオマーカーの調節のための酸化還元活性治療薬
WO2007035496A1 (en)	2005-09-15	2007-03-29	Edison Pharmaceuticals, Inc.	Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
EP1785133A1 (en) *	2005-11-10	2007-05-16	Laboratoires Fournier S.A.	Use of fenofibrate or a derivative thereof for preventing diabetic retinopathy
EP1986636B1 (en)	2006-02-22	2013-04-24	Edison Pharmaceuticals, Inc.	Phenol and 1,4-benzoquinone derivatives for use in the treatment of mitochondrial diseases
US7897326B2 (en)	2006-03-16	2011-03-01	University Of Pittsburgh-Of The Commonwealth System Of Higher Education	Peroxisome-proliferator activated receptor-alpha agonists for organ preservation
US20070225606A1 (en) *	2006-03-22	2007-09-27	Endothelix, Inc.	Method and apparatus for comprehensive assessment of vascular health
US20080027330A1 (en) *	2006-05-15	2008-01-31	Endothelix, Inc.	Risk assessment method for acute cardiovascular events
US20080081963A1 (en) *	2006-09-29	2008-04-03	Endothelix, Inc.	Methods and Apparatus for Profiling Cardiovascular Vulnerability to Mental Stress
KR100989093B1 (ko)	2008-01-18	2010-10-25	한화제약주식회사	생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물
CA2736250C (en)	2008-09-10	2016-12-20	Edison Pharmaceuticals, Inc.	Treatment of pervasive developmental disorders with redox-active therapeutics
EP2391219A4 (en) *	2009-01-29	2013-03-06	Joshua D Levine	METHOD FOR ADDING VEGETABLE SUBSTANCES / NUTRITIONAL AGGREGATES FOR PHARMACEUTICAL TREATMENT IN A PHARMACOTHERAPEUTIC TREATMENT
US8973851B2 (en)	2009-07-01	2015-03-10	The Procter & Gamble Company	Apparatus and methods for producing charged fluid droplets
US8772349B2 (en) *	2010-03-26	2014-07-08	Vivacell Biotechnology Espana, S.L.	Cannabinoid quinone derivatives
RU2554500C2 (ru) *	2013-09-20	2015-06-27	Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ)	Способ лечения ишемического инсульта
US10703701B2 (en)	2015-12-17	2020-07-07	Ptc Therapeutics, Inc.	Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders
US10881686B2 (en)	2017-10-27	2021-01-05	Zeta Biolongevity, Inc	Compositions and methods for treating and preventing proteinuria and endothelial erosion
CN110907407B (zh) *	2019-12-03	2022-02-25	东北石油大学	一种基于spr的高灵敏度光子准晶体光纤折射率传感器

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FR2627696B1 (fr)	1988-02-26	1991-09-13	Fournier Innovation Synergie	Nouvelle forme galenique du fenofibrate
FI102273B1 (fi)	1989-09-11	1998-11-13	Eisai Co Ltd	Kinonijohdannaiset, niiden valmistaminen ja niiden farmakologinen käyttö
FR2730231B1 (fr) *	1995-02-02	1997-04-04	Fournier Sca Lab	Association de fenofibrate et de vitamine e, utilisation en therapeutique
US6063407A (en) *	1995-02-16	2000-05-16	The General Hospital Corporation	Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
AU1856997A (en)	1996-02-02	1997-08-22	Merck & Co., Inc.	Method for raising hdl cholesterol levels
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2001
- 2001-10-23 AU AU2176502A patent/AU2176502A/xx active Pending
- 2001-10-23 DK DK01988586T patent/DK1328266T3/da active
- 2001-10-23 SK SK508-2003A patent/SK287992B6/sk unknown
- 2001-10-23 PL PL361635A patent/PL212952B1/pl not_active IP Right Cessation
- 2001-10-23 IL IL15552401A patent/IL155524A0/xx active IP Right Grant
- 2001-10-23 PT PT01988586T patent/PT1328266E/pt unknown
- 2001-10-23 JP JP2002537311A patent/JP4236464B2/ja not_active Expired - Fee Related
- 2001-10-23 EE EEP200300165A patent/EE05281B1/et not_active IP Right Cessation
- 2001-10-23 CZ CZ20031148A patent/CZ301282B6/cs not_active IP Right Cessation
- 2001-10-23 DZ DZ013442A patent/DZ3442A1/fr active
- 2001-10-23 US US10/399,639 patent/US7410983B2/en not_active Expired - Fee Related
- 2001-10-23 HU HU0303566A patent/HUP0303566A3/hu unknown
- 2001-10-23 KR KR1020037004793A patent/KR100862129B1/ko not_active Expired - Fee Related
- 2001-10-23 CA CA2426625A patent/CA2426625C/en not_active Expired - Fee Related
- 2001-10-23 AT AT01988586T patent/ATE316787T1/de active
- 2001-10-23 CN CNB01817972XA patent/CN1220488C/zh not_active Expired - Fee Related
- 2001-10-23 ES ES01988586T patent/ES2257457T3/es not_active Expired - Lifetime
- 2001-10-23 RU RU2003111175/15A patent/RU2003111175A/ru not_active Application Discontinuation
- 2001-10-23 EP EP01988586A patent/EP1328266B1/en not_active Expired - Lifetime
- 2001-10-23 DE DE60117046T patent/DE60117046T2/de not_active Expired - Lifetime
- 2001-10-23 BR BR0114701-3A patent/BR0114701A/pt not_active Application Discontinuation
- 2001-10-23 MX MXPA03003733A patent/MXPA03003733A/es active IP Right Grant
- 2001-10-23 WO PCT/EP2001/012425 patent/WO2002034259A1/en not_active Ceased
- 2001-10-25 TN TNTNSN01151A patent/TNSN01151A1/en unknown
- 2001-10-26 AR ARP010105032A patent/AR035071A1/es unknown
2003
- 2003-04-21 IL IL155524A patent/IL155524A/en not_active IP Right Cessation
- 2003-04-24 NO NO20031851A patent/NO332260B1/no not_active IP Right Cessation
- 2003-04-25 MA MA27124A patent/MA25847A1/fr unknown
- 2003-04-25 BG BG107765A patent/BG65979B1/bg unknown
2006
- 2006-03-21 CY CY20061100400T patent/CY1105007T1/el unknown

Also Published As

Publication number	Publication date
SK5082003A3 (en)	2003-11-04
KR100862129B1 (ko)	2008-10-09
CY1105007T1 (el)	2009-11-04
IL155524A (en)	2008-08-07
AU2176502A (en)	2002-05-06
SK287992B6 (sk)	2012-09-03
BG107765A (bg)	2004-02-27
EP1328266A1 (en)	2003-07-23
PT1328266E (pt)	2006-05-31
AR035071A1 (es)	2004-04-14
CZ301282B6 (cs)	2009-12-30
MXPA03003733A (es)	2004-10-15
NO332260B1 (no)	2012-08-13
MA25847A1 (fr)	2003-07-01
US20040022778A1 (en)	2004-02-05
JP4236464B2 (ja)	2009-03-11
US7410983B2 (en)	2008-08-12
EP1328266B1 (en)	2006-02-01
CA2426625A1 (en)	2002-05-02
NO20031851L (no)	2003-06-24
EE200300165A (et)	2003-06-16
DE60117046T2 (de)	2006-09-28
CN1220488C (zh)	2005-09-28
HUP0303566A3 (en)	2005-05-30
DE60117046D1 (de)	2006-04-13
KR20030055276A (ko)	2003-07-02
PL361635A1 (en)	2004-10-04
HK1057340A1 (en)	2004-04-02
HUP0303566A2 (hu)	2004-03-01
CA2426625C (en)	2010-06-01
JP2004512302A (ja)	2004-04-22
BG65979B1 (bg)	2010-08-31
BR0114701A (pt)	2003-11-18
CN1471390A (zh)	2004-01-28
NO20031851D0 (no)	2003-04-24
TNSN01151A1 (en)	2005-11-10
ATE316787T1 (de)	2006-02-15
RU2003111175A (ru)	2004-09-10
IL155524A0 (en)	2003-11-23
PL212952B1 (pl)	2012-12-31
DK1328266T3 (da)	2006-06-06
ES2257457T3 (es)	2006-08-01
WO2002034259A1 (en)	2002-05-02
DZ3442A1 (fr)	2002-05-02

Publication	Publication Date	Title
EE200300165A (et)	2003-06-16	Fenofibraadi ja koensüüm Q10 kombinatsioon endoteeli düsfunktsiooni ravimiseks
NO20014379L (no)	2001-11-07	Anvendelse av Xenon for behandling av Neurointoksikasjoner
EE200100659A (et)	2003-02-17	Diaminotiasoolid ja nende kasutamine proteiinikinaaside pärssimiseks
AU6048201A (en)	2001-12-17	Quinazoline derivatives for the treatment of tumours
AR028253A1 (es)	2003-04-30	Inhibidores de la glucogeno fosforilasa
IL184144A0 (en)	2007-10-31	Intermediates useful in the preparaiton of 2-aminocarbonyl-9h-purine derivatives
EE200200571A (et)	2004-04-15	Hüdroksüfenüülpiperidiin-4-ülideenmetüülbensamiidi derivaadid valu raviks
DK1176964T3 (da)	2007-01-15	Brug af ET743 til behandling af cancer
ITMI20001705A0 (it)	2000-07-25	Procedimento per la denitrificazione delle acque
PL356784A1 (pl)	2004-07-12	Substancja do zastosowania w leczeniu łuszczycy
NO20024924D0 (no)	2002-10-11	Anvendelse av bradykardiale substanser ved behandling av myokardiale sykdommer i forbindelse med hypertrofi og nyemedikamentkombinasjoner
EP1286721A4 (en)	2006-12-06	LENBAR GALLEN CATHETER
EE200200511A (et)	2004-02-16	Hüdroksüfenüülpiperasinüülmetüülbensamiidi derivaadid valu raviks
EE200200577A (et)	2004-06-15	Kinolinüülpiperidiin-4-ülideenmetüülbensamiidi derivaadid valu raviks
SI1197485T1 (en)	2004-12-31	Cyclobuten-dione derivatives for use in the treatment of artherosclerosis
HUP0302738A3 (en)	2010-01-28	Use of sarp-1 for the treatment and/or prevention of scleroderma
DK1257278T3 (da)	2006-06-12	Anvendelse af mirtazapin til behandling af sövnforstyrrelser
NO20025303L (no)	2002-11-05	Anvendelse av substituerte akryloyl-distamycin-derivater i behandlingen avtumorer assosiert med höye nivåer av glutation
PT1273556E (pt)	2006-08-31	Estacao de tratamento simbiotico de aguas residuais.
EE200300057A (et)	2004-12-15	Koostis vähi profülaktikaks ja raviks
GB0007217D0 (en)	2000-05-17	Materials and methods relating to the treatment of leukaemias
AU5565401A (en)	2001-11-07	Materials and methods for the treatment of depression
EE200200670A (et)	2004-08-16	S-metüüldihüdroziprasidoon psühhiaatriliste ja silmahaiguste raviks
DE60125959D1 (de)	2007-02-22	Unterscheidung zwischen gnrh-i und gnrh-ii
NO20022253D0 (no)	2002-05-10	Middel til behandling av hepatitt C

Legal Events

Date	Code	Title	Description
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2014-06-16	MM4A	Lapsed by not paying the annual fees	Effective date: 20131023