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EE05172B1 - Mesoprogestiinid (progesterooniretseptori modulaatorid) healoomuliste hormoons?ltuvate gnekoloogiliste haiguste raviks ja v„ltimiseks - Google Patents

Mesoprogestiinid (progesterooniretseptori modulaatorid) healoomuliste hormoons?ltuvate gnekoloogiliste haiguste raviks ja v„ltimiseks

Info

Publication number
EE05172B1
EE05172B1 EEP200200104A EEP200200104A EE05172B1 EE 05172 B1 EE05172 B1 EE 05172B1 EE P200200104 A EEP200200104 A EE P200200104A EE P200200104 A EEP200200104 A EE P200200104A EE 05172 B1 EE05172 B1 EE 05172B1
Authority
EE
Estonia
Prior art keywords
mesoprogestins
prevention
treatment
receptor modulators
progesterone receptor
Prior art date
Application number
EEP200200104A
Other languages
English (en)
Inventor
Chwalisz Kristof
Elger Walter
Schubert Gerd
Original Assignee
Jenapharm Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jenapharm Gmbh & Co. Kg filed Critical Jenapharm Gmbh & Co. Kg
Publication of EE200200104A publication Critical patent/EE200200104A/et
Publication of EE05172B1 publication Critical patent/EE05172B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
EEP200200104A 1999-08-31 2000-08-31 Mesoprogestiinid (progesterooniretseptori modulaatorid) healoomuliste hormoons?ltuvate gnekoloogiliste haiguste raviks ja v„ltimiseks EE05172B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38614199A 1999-08-31 1999-08-31
PCT/US2000/023770 WO2001015679A2 (en) 1999-08-31 2000-08-31 Mesoprogestins for the treatment and prevention of benign hormone dependent gynecological disorders

Publications (2)

Publication Number Publication Date
EE200200104A EE200200104A (et) 2003-04-15
EE05172B1 true EE05172B1 (et) 2009-06-15

Family

ID=23524338

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200104A EE05172B1 (et) 1999-08-31 2000-08-31 Mesoprogestiinid (progesterooniretseptori modulaatorid) healoomuliste hormoons?ltuvate gnekoloogiliste haiguste raviks ja v„ltimiseks

Country Status (34)

Country Link
EP (1) EP1229906B1 (et)
JP (1) JP2003535029A (et)
KR (3) KR20080066095A (et)
AR (1) AR025457A1 (et)
AT (1) ATE375160T1 (et)
AU (1) AU781840B2 (et)
BG (1) BG65817B1 (et)
BR (1) BR0014161A (et)
CA (1) CA2382580C (et)
CO (1) CO5200772A1 (et)
CZ (1) CZ2002704A3 (et)
DE (1) DE60036723T2 (et)
DK (1) DK1229906T3 (et)
EA (1) EA007854B1 (et)
EE (1) EE05172B1 (et)
ES (1) ES2295050T3 (et)
HR (1) HRP20020267A2 (et)
HU (1) HUP0202429A3 (et)
IL (1) IL148416A0 (et)
LT (1) LT5034B (et)
LV (1) LV12941B (et)
ME (1) MEP13808A (et)
MX (1) MXPA02002191A (et)
NO (1) NO20020999L (et)
NZ (1) NZ517471A (et)
PE (1) PE20010578A1 (et)
PL (1) PL198790B1 (et)
PT (1) PT1229906E (et)
RO (1) RO122179B1 (et)
RS (1) RS50283B (et)
SI (1) SI20852B (et)
SK (1) SK287192B6 (et)
UA (1) UA78184C2 (et)
WO (1) WO2001015679A2 (et)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003255355A1 (en) * 2002-08-02 2004-02-25 Schering Aktiengesellschaft Progesterone receptor modulators having an increased antigonadotropic activity for use in female fertility testing and hormone replacement therapy
DE10236405A1 (de) 2002-08-02 2004-02-19 Schering Ag Progesteronrezeptormodulatoren mit erhöhter antigonadotroper Aktivität für die weibliche Fertilitätskontrolle und Hormonersatztherapie
US20040097591A1 (en) * 2002-11-18 2004-05-20 Kristof Chwalisz Use of selective progesterone receptor modulators for the treatment of androgen deficiency
RU2301691C1 (ru) * 2005-12-20 2007-06-27 Государственное учреждение Научный центр акушерства, гинекологии и перинатологии Российской академии медицинских наук Способ восстановительного лечения женщин репродуктивного возраста с тазовыми перитонеальными спайками с фиксированной или субфиксированной ретродевиацией матки
DE102007011105A1 (de) 2007-03-02 2008-09-04 Bayer Schering Pharma Aktiengesellschaft Mineralcorticoid-Rezeptor-Antagonisten zur Behandlung von Endometriose
RU2339392C1 (ru) * 2007-05-21 2008-11-27 Федеральное Государственное учреждение Научный центр акушерства, гинекологии и перинатологии Росмедтехнологий Способ остановки маточных кровотечений в пубертатном периоде
WO2010147184A1 (ja) * 2009-06-17 2010-12-23 国立大学法人熊本大学 月経困難症の予防及び／又は治療薬
US8399432B2 (en) * 2009-10-27 2013-03-19 Lipogen Ltd. Compositions and methods of treatment for alleviating premenstrual syndrome symptoms
US20220339176A1 (en) * 2019-09-23 2022-10-27 The Board Of Trustees Of The Leland Stanford Junior University Methods of Treatments to Prolong Gestation and Complications of Menstruation or Gestation
US12426782B2 (en) 2020-11-06 2025-09-30 The Board Of Trustees Of The Leland Stanford Junior University Systems and temporal alignment methods for evaluation of gestational age and time to delivery

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3633244A1 (de) 1986-09-26 1988-03-31 Schering Ag Antigestagene zur hemmung der uterinen prostaglandinsynthese
DE4332284C2 (de) 1993-09-20 1997-05-28 Jenapharm Gmbh 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE4332283A1 (de) * 1993-09-20 1995-04-13 Jenapharm Gmbh Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US5681817A (en) * 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
US5576310A (en) * 1994-09-20 1996-11-19 Jenapharm Gmbh 11-benzaldoxime-17β-methoxy-17α-methoxymethyl-estrasdiene derivatives, methods for their production and pharmaceuticals containing such compounds
US5696133A (en) * 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
JPH10510840A (ja) * 1994-12-22 1998-10-20 リガンド・ファーマシューティカルズ・インコーポレイテッド ステロイド受容体モジュレーター化合物および方法
KR100370908B1 (ko) 1995-02-02 2003-04-10 쉐링 악티엔게젤샤프트 기능부전성자궁출혈치료용약제의제조에유용한프로게스테론길항제
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
US6861415B2 (en) * 1996-05-01 2005-03-01 The United States Of America As Represented By The Department Of Health And Human Services 21-substituted progesterone derivatives as new antiprogestational agents
WO1998005679A2 (en) * 1996-08-05 1998-02-12 Duke University Mixed agonists of the progesterone receptor and assays therefor
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
HUP0105134A2 (hu) * 1999-01-14 2002-04-29 Bayer Corporation Szubsztituált 2-arilimino-heterociklusok és ilyen vegyületeket tartalmazó készítmények progeszteron receptorhoz kötődő szerekként való alkalmazásra
AU4501800A (en) * 1999-05-04 2000-11-17 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods

Also Published As

Publication number Publication date
AU6946600A (en) 2001-03-26
SI20852A (sl) 2002-10-31
HUP0202429A3 (en) 2004-04-28
WO2001015679A2 (en) 2001-03-08
DE60036723T2 (de) 2008-07-17
EA007854B1 (ru) 2007-02-27
EP1229906A2 (en) 2002-08-14
KR100755109B1 (ko) 2007-09-04
LT2002031A (en) 2003-02-25
KR20070058023A (ko) 2007-06-07
UA78184C2 (en) 2007-03-15
CZ2002704A3 (cs) 2003-02-12
NO20020999L (no) 2002-03-14
JP2003535029A (ja) 2003-11-25
KR100864547B1 (ko) 2008-10-20
DK1229906T3 (da) 2008-02-11
LT5034B (lt) 2003-07-25
EE200200104A (et) 2003-04-15
WO2001015679A3 (en) 2001-11-22
CA2382580C (en) 2009-05-19
PL353930A1 (en) 2003-12-15
KR20020027616A (ko) 2002-04-13
EP1229906B1 (en) 2007-10-10
YU14002A (sh) 2006-01-16
LV12941B (en) 2003-06-20
NO20020999D0 (no) 2002-02-28
AR025457A1 (es) 2002-11-27
EA200200282A1 (ru) 2002-10-31
BG65817B1 (bg) 2010-01-29
AU781840B2 (en) 2005-06-16
MXPA02002191A (es) 2002-09-30
BR0014161A (pt) 2002-05-21
RO122179B1 (ro) 2009-02-27
PE20010578A1 (es) 2001-06-04
RS50283B (sr) 2009-09-08
PT1229906E (pt) 2008-01-18
KR20080066095A (ko) 2008-07-15
HUP0202429A2 (en) 2002-10-28
ATE375160T1 (de) 2007-10-15
NZ517471A (en) 2004-02-27
IL148416A0 (en) 2002-09-12
BG106442A (bg) 2002-09-30
ES2295050T3 (es) 2008-04-16
SK287192B6 (sk) 2010-02-08
HRP20020267A2 (en) 2004-04-30
MEP13808A (en) 2010-06-10
SK2992002A3 (en) 2002-07-02
SI20852B (sl) 2009-06-30
CO5200772A1 (es) 2002-09-27
CA2382580A1 (en) 2001-03-08
PL198790B1 (pl) 2008-07-31
DE60036723D1 (de) 2007-11-22

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Legal Events

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GB1A Change in the ownership or in the address of the owner
HB1A Correction of owner name or address
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KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20100831