ECSP22081150A - Composición farmacéutica para la prevención o tratamiento de enfermedad infecciosa viral de arn epidémica - Google Patents
Composición farmacéutica para la prevención o tratamiento de enfermedad infecciosa viral de arn epidémicaInfo
- Publication number
- ECSP22081150A ECSP22081150A ECSENADI202281150A ECDI202281150A ECSP22081150A EC SP22081150 A ECSP22081150 A EC SP22081150A EC SENADI202281150 A ECSENADI202281150 A EC SENADI202281150A EC DI202281150 A ECDI202281150 A EC DI202281150A EC SP22081150 A ECSP22081150 A EC SP22081150A
- Authority
- EC
- Ecuador
- Prior art keywords
- epidemic
- prevention
- treatment
- infectious disease
- rna viral
- Prior art date
Links
- 208000035473 Communicable disease Diseases 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 3
- 230000003612 virological effect Effects 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000025721 COVID-19 Diseases 0.000 abstract 2
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 abstract 2
- 229960004191 artemisinin Drugs 0.000 abstract 2
- 229930101531 artemisinin Natural products 0.000 abstract 2
- DJUFPMUQJKWIJB-UHFFFAOYSA-N pyronaridine Chemical compound C12=NC(OC)=CC=C2N=C2C=C(Cl)C=CC2=C1NC(C=C(CN1CCCC1)C=1O)=CC=1CN1CCCC1 DJUFPMUQJKWIJB-UHFFFAOYSA-N 0.000 abstract 2
- 229950011262 pyronaridine Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se relaciona a un uso de pironaridina o una sal farmacéuticamente aceptable de la misma, y/o artemisinina o un derivado de la misma para la prevención o tratamiento de una enfermedad infecciosa viral de ARN epidémica, y más específicamente, a una composición farmacéutica para la prevención o tratamiento de una enfermedad infecciosa viral de ARN epidémica, en particular, Enfermedad de Coronavirus 2019 (COVID-19), la composición que comprende una cantidad terapéuticamente efectiva de pironaridina o una sal farmacéuticamente aceptable de la misma, y/o artemisinina o un derivado de la misma, junto con un portador farmacéuticamente aceptable.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20200037135 | 2020-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP22081150A true ECSP22081150A (es) | 2023-02-28 |
Family
ID=77892085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSENADI202281150A ECSP22081150A (es) | 2020-03-26 | 2022-10-24 | Composición farmacéutica para la prevención o tratamiento de enfermedad infecciosa viral de arn epidémica |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US12485116B2 (es) |
| EP (1) | EP4129290B1 (es) |
| JP (1) | JP2023519277A (es) |
| KR (2) | KR102828536B1 (es) |
| CN (1) | CN115666572B (es) |
| AU (1) | AU2021244009A1 (es) |
| BR (1) | BR112022019198A2 (es) |
| CA (1) | CA3172672A1 (es) |
| CL (1) | CL2022002588A1 (es) |
| CO (1) | CO2022014992A2 (es) |
| CR (1) | CR20220508A (es) |
| EC (1) | ECSP22081150A (es) |
| ES (1) | ES3040436T3 (es) |
| IL (1) | IL296721A (es) |
| MX (1) | MX2022011885A (es) |
| PE (1) | PE20230041A1 (es) |
| PH (1) | PH12022552516A1 (es) |
| PL (1) | PL4129290T3 (es) |
| UA (1) | UA130231C2 (es) |
| WO (1) | WO2021194290A1 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111803491A (zh) * | 2020-07-24 | 2020-10-23 | 中国人民解放军军事科学院军事医学研究院 | 青蒿素类化合物在治疗冠状病毒感染方面的应用 |
| WO2022076565A1 (en) * | 2020-10-07 | 2022-04-14 | Sorrento Therapeutics, Inc. | Salicylanilide analogs for use in the treatment of coronavirus |
| WO2023172065A1 (ko) * | 2022-03-08 | 2023-09-14 | 주식회사 위바이오트리 | 니클로사마이드 또는 이의 약학적으로 허용 가능한 염을 포함하는 항 바이러스용 또는 항암용 조성물 및 이의 제조방법 |
| CN116966178B (zh) * | 2022-04-29 | 2025-10-03 | 成都贝诺科成生物科技有限公司 | 一种氨基硝基噻唑衍生物在制备预防和治疗病毒感染及其引起的相关疾病的药物中的用途 |
| WO2025153638A1 (en) * | 2024-01-19 | 2025-07-24 | Pamoja Therapeutics Bv | Highly concentrated liquid aqueous pyronaridine formulation |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19843222A1 (de) * | 1998-09-22 | 2000-03-30 | Hassan Jomaa | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
| WO2004071506A1 (en) | 2003-02-12 | 2004-08-26 | Georgetown University | Use of artemisinin for treating tumors induced by oncogenic viruses and for treating viral infections |
| US20110206636A1 (en) * | 2003-09-16 | 2011-08-25 | Kemin Foods, LLC | Use of Endoperoxides for the Treatment of Infections Caused by Flaviviridae, Including Hepatitis C, Bovine Viral Diarrhea and Classical Swine Fever Virus |
| KR100623322B1 (ko) | 2004-11-02 | 2006-09-19 | 신풍제약주식회사 | 경구투여용 항말라리아 배합 제제 및 그의 제조방법 |
| DE102006026464A1 (de) | 2006-06-01 | 2007-12-06 | Virologik Gmbh Innovationszentrum Medizintechnik Und Pharma | Pharmazeutische Zusammensetzung zur Behandlung von Virusinfektionen und / oder Tumorerkrankungen durch Inhibition der Proteinfaltung und des Proteinabbaus |
| CN101857613B (zh) | 2010-06-03 | 2012-04-18 | 中国科学院新疆理化技术研究所 | 一枝蒿酮酸糖酯类衍生物及其制备方法和用途 |
| CN101898966B (zh) | 2010-07-15 | 2013-04-17 | 中国科学院新疆理化技术研究所 | 含哌嗪环的一枝蒿酮酸酯类衍生物及其制备方法 |
| JP5750274B2 (ja) * | 2011-02-15 | 2015-07-15 | 株式会社ブリヂストン | ゴムクローラ |
| US9675582B2 (en) | 2011-10-25 | 2017-06-13 | U.S. Phytotherapy, Inc. | Alternative ACT with natural botanical active GRAS ingredients for treatment and prevention of the Zika virus |
| US20140011829A1 (en) | 2012-07-06 | 2014-01-09 | Robert Lewis Steele | Artemisinin-Based Combination Therapy For Treating Viral Mediated Disease |
| CN105168500B (zh) | 2015-09-11 | 2018-08-17 | 青岛大学附属医院 | 一种用于治疗小儿口腔溃疡的药物组合物及其制备方法 |
| US11696914B1 (en) * | 2019-11-06 | 2023-07-11 | Collaborations Pharmaceuticals, Inc. | Use of pyronaridine, tilorone, and quinacrine against Marburg virus and other virus infections |
| EP4121041A4 (en) | 2020-03-18 | 2024-04-03 | GMP Biotechnology Limited | TGF-BETA INHIBITION, AGENTS AND COMPOSITION FOR IT |
-
2021
- 2021-03-25 WO PCT/KR2021/003742 patent/WO2021194290A1/ko not_active Ceased
- 2021-03-25 ES ES21775231T patent/ES3040436T3/es active Active
- 2021-03-25 US US17/914,425 patent/US12485116B2/en active Active
- 2021-03-25 CN CN202180032608.0A patent/CN115666572B/zh active Active
- 2021-03-25 PE PE2022002097A patent/PE20230041A1/es unknown
- 2021-03-25 BR BR112022019198A patent/BR112022019198A2/pt unknown
- 2021-03-25 CR CR20220508A patent/CR20220508A/es unknown
- 2021-03-25 JP JP2022557949A patent/JP2023519277A/ja active Pending
- 2021-03-25 CA CA3172672A patent/CA3172672A1/en active Pending
- 2021-03-25 PL PL21775231.0T patent/PL4129290T3/pl unknown
- 2021-03-25 IL IL296721A patent/IL296721A/en unknown
- 2021-03-25 EP EP21775231.0A patent/EP4129290B1/en active Active
- 2021-03-25 UA UAA202204063A patent/UA130231C2/uk unknown
- 2021-03-25 KR KR1020210039184A patent/KR102828536B1/ko active Active
- 2021-03-25 PH PH1/2022/552516A patent/PH12022552516A1/en unknown
- 2021-03-25 AU AU2021244009A patent/AU2021244009A1/en active Pending
- 2021-03-25 MX MX2022011885A patent/MX2022011885A/es unknown
-
2022
- 2022-09-23 CL CL2022002588A patent/CL2022002588A1/es unknown
- 2022-10-21 CO CONC2022/0014992A patent/CO2022014992A2/es unknown
- 2022-10-24 EC ECSENADI202281150A patent/ECSP22081150A/es unknown
-
2024
- 2024-06-25 KR KR1020240082697A patent/KR102910416B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| PL4129290T3 (pl) | 2025-10-13 |
| CA3172672A1 (en) | 2021-09-30 |
| CR20220508A (es) | 2023-04-25 |
| CN115666572B (zh) | 2025-03-28 |
| IL296721A (en) | 2022-11-01 |
| BR112022019198A2 (pt) | 2022-11-16 |
| EP4129290A1 (en) | 2023-02-08 |
| PE20230041A1 (es) | 2023-01-10 |
| WO2021194290A1 (ko) | 2021-09-30 |
| US20230132036A1 (en) | 2023-04-27 |
| US12485116B2 (en) | 2025-12-02 |
| KR102828536B1 (ko) | 2025-07-02 |
| UA130231C2 (uk) | 2025-12-24 |
| KR20240108337A (ko) | 2024-07-09 |
| ES3040436T3 (en) | 2025-10-30 |
| AU2021244009A1 (en) | 2022-10-27 |
| CL2022002588A1 (es) | 2023-05-26 |
| CN115666572A (zh) | 2023-01-31 |
| EP4129290C0 (en) | 2025-07-09 |
| KR20210120891A (ko) | 2021-10-07 |
| EP4129290B1 (en) | 2025-07-09 |
| JP2023519277A (ja) | 2023-05-10 |
| CO2022014992A2 (es) | 2022-11-29 |
| MX2022011885A (es) | 2022-10-21 |
| KR102910416B1 (ko) | 2026-01-14 |
| PH12022552516A1 (en) | 2022-11-07 |
| EP4129290A4 (en) | 2023-08-30 |
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