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ECSP12012274A - Composición farmacèutica de ibuprofeno para inyecciòn - Google Patents

Composición farmacèutica de ibuprofeno para inyecciòn

Info

Publication number
ECSP12012274A
ECSP12012274A ECSP12012274A ECSP12012274A EC SP12012274 A ECSP12012274 A EC SP12012274A EC SP12012274 A ECSP12012274 A EC SP12012274A EC SP12012274 A ECSP12012274 A EC SP12012274A
Authority
EC
Ecuador
Prior art keywords
ibuprofen
injection
pharmaceutical composition
containers
autoclaving
Prior art date
Application number
Other languages
English (en)
Inventor
Andéchaga Ignacio Ortúzar
Gutiérrez Mario Ortúzar
Original Assignee
Spain Pharma S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43589415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP12012274(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Spain Pharma S A filed Critical Spain Pharma S A
Publication of ECSP12012274A publication Critical patent/ECSP12012274A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Composición farmacéutica de ibuprofeno para inyección que comprende una solución acuosa de ibuprofeno y trometamol. Estas composiciones exhiben una pérdida de principio activo mínima y una producción de impurezas aceptable tras el autoclavado, propiedades que han sido demostradas en distintos tipos de envases, tales como envases de material plástico del tipo polipropileno, PVC y polietileno, así como en envases de vidrio. Estas composiciones, tras haber sido sometidas a autoclavado, siguen cumpliendo todas las especificaciones técnicas correspondientes de la Farmacopea Europea y de la de EE.UU.
ECSP12012274 2010-05-18 2012-10-17 Composición farmacèutica de ibuprofeno para inyecciòn ECSP12012274A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ES2010/070330 WO2011144766A1 (es) 2010-05-18 2010-05-18 Composición farmacéutica de ibuprofeno para inyección

Publications (1)

Publication Number Publication Date
ECSP12012274A true ECSP12012274A (es) 2013-02-28

Family

ID=43589415

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12012274 ECSP12012274A (es) 2010-05-18 2012-10-17 Composición farmacèutica de ibuprofeno para inyecciòn

Country Status (35)

Country Link
US (1) US9114165B2 (es)
EP (1) EP2571488B2 (es)
JP (1) JP6018048B2 (es)
KR (1) KR101770808B1 (es)
CN (1) CN102892410B (es)
AU (1) AU2011254583B2 (es)
BR (1) BR112012029171B1 (es)
CA (1) CA2798575C (es)
CL (1) CL2012003119A1 (es)
CO (1) CO6650419A2 (es)
CR (1) CR20120559A (es)
CY (1) CY1115394T1 (es)
DK (1) DK2571488T4 (es)
EC (1) ECSP12012274A (es)
ES (1) ES2478491T5 (es)
HR (1) HRP20140622T4 (es)
IL (1) IL222497A0 (es)
MA (1) MA34176B1 (es)
ME (1) ME01834B (es)
MX (1) MX2012013402A (es)
MY (1) MY160302A (es)
NZ (1) NZ602957A (es)
PE (1) PE20130374A1 (es)
PH (1) PH12012502274A1 (es)
PL (1) PL2571488T5 (es)
PT (1) PT2571488E (es)
RS (1) RS53408B2 (es)
RU (1) RU2012154628A (es)
SG (1) SG185061A1 (es)
SI (1) SI2571488T2 (es)
SM (1) SMT201400103B (es)
TN (1) TN2012000487A1 (es)
UA (1) UA103290C2 (es)
WO (2) WO2011144766A1 (es)
ZA (1) ZA201207948B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9072710B2 (en) * 2012-03-16 2015-07-07 Cumberland Pharmaceuticals Inc. Injectable ibuprofen formulation
CN104323988A (zh) * 2014-11-27 2015-02-04 北京蓝丹医药科技有限公司 一种用于注射的右旋布洛芬药物组合物
CN105055389B (zh) * 2015-08-03 2018-08-10 北京蓝丹医药科技有限公司 一种用于早产儿先天性心脏病的布洛芬药物组合物
CN105997901A (zh) * 2016-07-27 2016-10-12 济南东方开元医药新技术有限公司 小儿注射用布洛芬氨丁三醇冻干粉针组合物及制备方法
EP3893840B1 (en) * 2018-12-14 2025-07-09 Fresenius Kabi Austria GmbH Pharmaceutical compositions for parenteral administration comprising ibuprofen and a phosphate buffer
CN112526013B (zh) * 2020-11-20 2022-09-06 人福普克药业（武汉）有限公司 超高液相色谱法检测布洛芬药物中有关物质浓度方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19912436A1 (de) * 1999-03-19 2000-09-21 Merckle Gmbh Ibuprofen-Lösung
US20040132823A1 (en) 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
AU2002224475B2 (en) 2001-11-02 2008-01-17 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ITMI20040235A1 (it) 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale

Also Published As

Publication number Publication date
BR112012029171A2 (pt) 2017-07-18
PL2571488T5 (pl) 2018-07-31
CA2798575A1 (en) 2011-11-24
EP2571488A1 (en) 2013-03-27
US20130231390A1 (en) 2013-09-05
MA34176B1 (fr) 2013-04-03
CO6650419A2 (es) 2013-04-15
US9114165B2 (en) 2015-08-25
HK1177424A1 (en) 2013-08-23
IL222497A0 (en) 2012-12-31
ME01834B (me) 2014-12-20
SI2571488T2 (sl) 2017-09-29
MX2012013402A (es) 2013-01-17
JP2013529205A (ja) 2013-07-18
PT2571488E (pt) 2014-07-25
CN102892410B (zh) 2014-12-10
KR101770808B1 (ko) 2017-08-23
RS53408B (sr) 2014-10-31
RU2012154628A (ru) 2014-06-27
CL2012003119A1 (es) 2013-06-07
ES2478491T3 (es) 2014-07-22
ZA201207948B (en) 2013-06-26
ES2478491T5 (es) 2017-11-21
CY1115394T1 (el) 2017-01-04
KR20130109007A (ko) 2013-10-07
JP6018048B2 (ja) 2016-11-02
TN2012000487A1 (en) 2014-04-01
EP2571488B1 (en) 2014-06-18
HRP20140622T1 (en) 2014-09-26
HRP20140622T4 (hr) 2017-10-06
SI2571488T1 (sl) 2014-09-30
UA103290C2 (ru) 2013-09-25
SG185061A1 (en) 2012-12-28
WO2011144677A1 (en) 2011-11-24
BR112012029171B1 (pt) 2021-05-25
RS53408B2 (sr) 2018-06-29
MY160302A (en) 2017-02-28
DK2571488T3 (da) 2014-07-14
NZ602957A (en) 2014-09-26
EP2571488B2 (en) 2017-07-26
AU2011254583B2 (en) 2014-04-10
CR20120559A (es) 2013-02-15
PH12012502274A1 (en) 2013-02-04
DK2571488T4 (en) 2017-08-28
WO2011144766A1 (es) 2011-11-24
PE20130374A1 (es) 2013-03-30
PL2571488T3 (pl) 2014-12-31
AU2011254583A1 (en) 2012-11-08
CA2798575C (en) 2018-08-28
CN102892410A (zh) 2013-01-23
SMT201400103B (it) 2014-09-08

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