[go: up one dir, main page]

ECSP10010412A - Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicótico - Google Patents

Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicótico

Info

Publication number
ECSP10010412A
ECSP10010412A EC2010010412A ECSP10010412A ECSP10010412A EC SP10010412 A ECSP10010412 A EC SP10010412A EC 2010010412 A EC2010010412 A EC 2010010412A EC SP10010412 A ECSP10010412 A EC SP10010412A EC SP10010412 A ECSP10010412 A EC SP10010412A
Authority
EC
Ecuador
Prior art keywords
compound
diamine
tiazol
dihidro
etil
Prior art date
Application number
EC2010010412A
Other languages
English (en)
Inventor
Rebecca Urbanek
Jian Wei Liu
William C Blackwell Iii
James Hulsizer
Gary Steelman
Dan Widzowski
Ye Wu
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP10010412A publication Critical patent/ECSP10010412A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se refiere al compuesto de Fórmula I y sus sales farmacéuticamente aceptables: (R)-N*6*-etil-6,7-dihidro-5H-indeno[5,6-d]tiazol-2,6-diamina. Esta invención también se refiere a métodos para sintetizar, métodos para utilizar y a composiciones farmacéuticas que comprenden el compuesto de Fórmula I y sus sales.
EC2010010412A 2008-02-21 2010-08-20 Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicótico ECSP10010412A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3033208P 2008-02-21 2008-02-21

Publications (1)

Publication Number Publication Date
ECSP10010412A true ECSP10010412A (es) 2010-09-30

Family

ID=40985770

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010412A ECSP10010412A (es) 2008-02-21 2010-08-20 Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicótico

Country Status (24)

Country Link
US (1) US20090215841A1 (es)
EP (1) EP2254876A4 (es)
JP (1) JP2011512407A (es)
KR (1) KR20100122487A (es)
CN (1) CN101952266A (es)
AR (1) AR070618A1 (es)
AU (1) AU2009215920A1 (es)
BR (1) BRPI0907158A2 (es)
CA (1) CA2716215A1 (es)
CL (1) CL2009000392A1 (es)
CO (1) CO6300849A2 (es)
CR (1) CR11639A (es)
DO (1) DOP2010000257A (es)
EA (1) EA201001095A1 (es)
EC (1) ECSP10010412A (es)
IL (1) IL206817A0 (es)
MX (1) MX2010008923A (es)
NI (1) NI201000141A (es)
PE (1) PE20091566A1 (es)
SA (1) SA109300120B1 (es)
TW (1) TW200940516A (es)
UY (1) UY31668A1 (es)
WO (1) WO2009105026A1 (es)
ZA (1) ZA201004800B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6958797B2 (ja) * 2016-06-21 2021-11-02 浙江柏拉阿図医薬科技有限公司 Ｃ型肝炎ウイルス阻害剤およびその使用
CN109134600B (zh) * 2017-06-19 2021-07-20 杭州国谋生物科技有限公司 作为丙型肝炎抑制剂的烷基及杂环化合物及其在药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9802360D0 (sv) * 1998-07-01 1998-07-01 Wikstroem Hakan Vilhelm New 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins ((basic)-N-substituted and (basic)-N,N-disubstituted derivatives of 2,6-diamino-thiazolo(4,5-f)indan and 2,7-di-amino-thiazolo(4,5-g)tetralin
WO2005084205A2 (en) * 2004-02-27 2005-09-15 Teva Pharmaceutical Industries, Ltd. Diamino thiazoloindan derivatives and their use

Also Published As

Publication number Publication date
EP2254876A1 (en) 2010-12-01
MX2010008923A (es) 2010-09-07
EP2254876A4 (en) 2012-10-31
WO2009105026A1 (en) 2009-08-27
TW200940516A (en) 2009-10-01
JP2011512407A (ja) 2011-04-21
UY31668A1 (es) 2009-09-30
AR070618A1 (es) 2010-04-21
EA201001095A1 (ru) 2011-04-29
CR11639A (es) 2010-10-05
NI201000141A (es) 2011-03-24
US20090215841A1 (en) 2009-08-27
CN101952266A (zh) 2011-01-19
AU2009215920A1 (en) 2009-08-27
DOP2010000257A (es) 2010-10-31
CA2716215A1 (en) 2009-08-27
CL2009000392A1 (es) 2010-09-24
IL206817A0 (en) 2010-12-30
SA109300120B1 (ar) 2011-10-08
BRPI0907158A2 (pt) 2015-07-07
KR20100122487A (ko) 2010-11-22
PE20091566A1 (es) 2009-11-06
CO6300849A2 (es) 2011-07-21
ZA201004800B (en) 2012-06-27

Similar Documents

Publication Publication Date Title
CO6311079A2 (es) Derivados de aminodihidrotiazina como inhibidores de la enzima bace para el tratamiento de la enfermedad de alzheimer
CO6321282A2 (es) Derivados de piperidinilindol como inhibidores de aldosterona sintasa
SV2010003598A (es) Derivados de tiazol usados como inhibidores de pi 3-cinasa
CR20140392A (es) Dihidropirazolonas sustituidas
GT200800242A (es) Derivados biciclicos como inhibidores de cetp
SV2010003472A (es) Compuestos de pirazol
CO6300954A2 (es) Derivados de tienopiridinonas como activadores de proteina quinasa activados por ampk
ECSP10010654A (es) Derivados de tienopiridonas como activadores de proteína quinasa activados por amp (ampk)
UY33337A (es) DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
ECSP088700A (es) Acidos 4-fenil-tiazol-5-carboxilicos y amidas de acidos 4-fenil-tiazol-5-carboxilicos como inhibidores de la plk1
CU23889B1 (es) 5-[(3,3,3-trifluoro-2-hidroxi-1-arilpropil)amino]-1h-quinolin-2-onas, un proceso para su producción y su uso como agentes antinflamatorios
ECSP099565A (es) Compuesto de 2-amino pirimidina
UY32744A (es) Derivados de 2-carboxamida-7-piperazinil-benzofurano 774
GT200600117A (es) Nuevos compuestos farmaceuticos
BR112012009311A2 (pt) composto, composição farmacêutica, e, uso do composto
UY32713A (es) Nuevos agentes antihelmínticos heterocíclicos y su uso.
ECSP099506A (es) Derivados de 2-quinolinona y 2 quinoxalinona y su utilización como agentes anti bacterianos
DOP2006000017A (es) Pirazolopiridinas y sales de las mismas, una composición farmaceútica que comprende dichos compuestos, un método para prepararlos y su uso
ECSP10010200A (es) Derivados de pirazol como inhibidores de 5-lo
CU20110108A7 (es) [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos
UY32042A (es) Compuestos de 2-aminopirimidina como potentes inhibidores de hsp-90
UY29358A1 (es) Tiazolidinonas, su preparacion y su uso como medicamento
ECSP10010412A (es) Compuesto (r)-n*6*-etil-6,7-dihidro-5h-indeno(5,6-d)tiazol-2,6-diamina y su uso como antipsicótico
ECSP11011150A (es) Derivados de arilciclopropilacetamida útiles como activadores de glucoquinasa
PA8666801A1 (es) Derivado de 5h-bensociclohepteno, procedimiento para su preparacion y su uso como antiinflamatorios