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EA200500814A1 - Производные пирролопиримидина - Google Patents

Производные пирролопиримидина

Info

Publication number
EA200500814A1
EA200500814A1 EA200500814A EA200500814A EA200500814A1 EA 200500814 A1 EA200500814 A1 EA 200500814A1 EA 200500814 A EA200500814 A EA 200500814A EA 200500814 A EA200500814 A EA 200500814A EA 200500814 A1 EA200500814 A1 EA 200500814A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formula
compounds
relates
pyrropolymidinine
derivatives
Prior art date
Application number
EA200500814A
Other languages
English (en)
Inventor
Джоэл Томас Аркари
Джиншан Чен
Сьюзан Лагрега
Мэттью Арнольд Маркс
Мэттью Дейвид Уэссел
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32682064&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200500814(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200500814A1 publication Critical patent/EA200500814A1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Изобретение относится к соединениям формулы 1 или их фармацевтически приемлемой соли, пролекарству или гидратам, где Q, A, L, R, Rи Rявляются такими, как определено здесь. Изобретение также относится к фармацевтическим композициям, содержащим соединения формулы 1, и к способам лечения гиперпролиферативных расстройств у млекопитающего путем введения соединений формулы 1.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200500814A 2002-12-19 2003-12-08 Производные пирролопиримидина EA200500814A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43456802P 2002-12-19 2002-12-19
PCT/IB2003/005841 WO2004056830A1 (en) 2002-12-19 2003-12-08 Pyrrolopyrimidine derivatives

Publications (1)

Publication Number Publication Date
EA200500814A1 true EA200500814A1 (ru) 2006-02-24

Family

ID=32682064

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500814A EA200500814A1 (ru) 2002-12-19 2003-12-08 Производные пирролопиримидина

Country Status (34)

Country Link
US (1) US7271262B2 (ru)
EP (1) EP1578751B1 (ru)
JP (1) JP4057013B2 (ru)
KR (2) KR20070087020A (ru)
CN (1) CN1726218A (ru)
AP (1) AP2005003342A0 (ru)
AR (1) AR042509A1 (ru)
AT (1) ATE512965T1 (ru)
AU (1) AU2003286317A1 (ru)
BR (1) BR0317524A (ru)
CA (1) CA2510853C (ru)
EA (1) EA200500814A1 (ru)
EC (1) ECSP055867A (ru)
ES (1) ES2364649T3 (ru)
GT (1) GT200300289A (ru)
HN (1) HN2003000416A (ru)
HR (1) HRP20050560A2 (ru)
IS (1) IS7872A (ru)
MA (1) MA27568A1 (ru)
MX (1) MXPA05006793A (ru)
NL (1) NL1025068C2 (ru)
NO (1) NO20052802L (ru)
NZ (1) NZ540456A (ru)
OA (1) OA12976A (ru)
PA (1) PA8591701A1 (ru)
PE (1) PE20040914A1 (ru)
PL (1) PL377774A1 (ru)
RS (1) RS20050469A (ru)
TN (1) TNSN05165A1 (ru)
TW (1) TW200423939A (ru)
UA (1) UA80171C2 (ru)
UY (1) UY28132A1 (ru)
WO (1) WO2004056830A1 (ru)
ZA (1) ZA200504440B (ru)

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