EA200300206A1 - Производные феноксибензиламина в качестве ингибиторов повторного поглощения серотонина - Google Patents
Производные феноксибензиламина в качестве ингибиторов повторного поглощения серотонинаInfo
- Publication number
- EA200300206A1 EA200300206A1 EA200300206A EA200300206A EA200300206A1 EA 200300206 A1 EA200300206 A1 EA 200300206A1 EA 200300206 A EA200300206 A EA 200300206A EA 200300206 A EA200300206 A EA 200300206A EA 200300206 A1 EA200300206 A1 EA 200300206A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- alkyl
- heterocyclic ring
- serotonin
- general formula
- phenoxybenzylamine
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 title 2
- 238000010521 absorption reaction Methods 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- YXMXAXHPRPWBJB-UHFFFAOYSA-N n-phenoxy-1-phenylmethanamine Chemical class C=1C=CC=CC=1CNOC1=CC=CC=C1 YXMXAXHPRPWBJB-UHFFFAOYSA-N 0.000 title 1
- 229940076279 serotonin Drugs 0.000 title 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 229910052717 sulfur Inorganic materials 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002393 azetidinyl group Chemical group 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/20—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/06—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0021593A GB0021593D0 (en) | 2000-08-31 | 2000-08-31 | Diphenyl ether compounds useful in therapy |
| GB0107116A GB0107116D0 (en) | 2001-03-21 | 2001-03-21 | Novel compounds |
| PCT/IB2001/001521 WO2002018333A1 (en) | 2000-08-31 | 2001-08-22 | Phenoxybenzylamine derivatives as selective serotonin re-uptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200300206A1 true EA200300206A1 (ru) | 2003-06-26 |
Family
ID=26244953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200300206A EA200300206A1 (ru) | 2000-08-31 | 2001-08-22 | Производные феноксибензиламина в качестве ингибиторов повторного поглощения серотонина |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP1313701A1 (no) |
| JP (1) | JP2004507523A (no) |
| KR (1) | KR20030029889A (no) |
| CN (1) | CN1449380A (no) |
| AP (1) | AP2001002265A0 (no) |
| AR (1) | AR031867A1 (no) |
| AU (1) | AU2001278650A1 (no) |
| BG (1) | BG107544A (no) |
| BR (1) | BR0113610A (no) |
| CA (1) | CA2420969A1 (no) |
| CZ (1) | CZ2003467A3 (no) |
| DO (1) | DOP2001000242A (no) |
| DZ (1) | DZ3414A1 (no) |
| EA (1) | EA200300206A1 (no) |
| EE (1) | EE200300084A (no) |
| HN (1) | HN2001000191A (no) |
| HR (1) | HRP20030141A2 (no) |
| HU (1) | HUP0303385A2 (no) |
| IL (1) | IL154343A0 (no) |
| IS (1) | IS6704A (no) |
| MA (1) | MA26945A1 (no) |
| MX (1) | MXPA03001848A (no) |
| NO (1) | NO20030842L (no) |
| NZ (1) | NZ523951A (no) |
| OA (1) | OA12372A (no) |
| PA (1) | PA8526701A1 (no) |
| PE (1) | PE20020346A1 (no) |
| PL (1) | PL360743A1 (no) |
| SK (1) | SK2012003A3 (no) |
| TN (1) | TNSN01131A1 (no) |
| UY (1) | UY26924A1 (no) |
| WO (1) | WO2002018333A1 (no) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403597B1 (en) * | 1997-10-28 | 2002-06-11 | Vivus, Inc. | Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation |
| US6436938B1 (en) * | 2001-01-22 | 2002-08-20 | Pfizer Inc. | Combination treatment for depression |
| US20020107244A1 (en) * | 2001-02-02 | 2002-08-08 | Howard Harry R. | Combination treatment for depression |
| US20020183306A1 (en) * | 2001-05-30 | 2002-12-05 | Pfizer Inc. | Combination treatment for sleep disorders including sleep apnea |
| GB0318706D0 (en) * | 2003-08-08 | 2003-09-10 | Pfizer Ltd | Selective serotonin reuptake inhibitors in the treatment of disease |
| AU2005214167B2 (en) | 2004-02-13 | 2008-08-07 | Warner-Lambert Company Llc | Androgen receptor modulators |
| CA2563291A1 (en) | 2004-04-13 | 2005-10-27 | Warner-Lambert Company Llc | 4-cyano-phenoxy-alkyl carboxyl derivatives as androgen modulators |
| EP1740533A1 (en) | 2004-04-22 | 2007-01-10 | Warner-Lambert Company LLC | Androgen modulators |
| BRPI0513020A (pt) | 2004-07-08 | 2008-04-22 | Warner Lambert Co | moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação |
| WO2006018723A2 (en) * | 2004-08-18 | 2006-02-23 | Warner-Lambert Company Llc | Androgen modulators |
| CA2580024A1 (en) * | 2004-09-10 | 2006-03-16 | Pfizer Products Inc. | Therapeutic diphenyl ether ligands |
| TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
| WO2007010350A1 (en) * | 2005-07-19 | 2007-01-25 | Pfizer Products Inc. | Synthesis of therapeutic diphenyl ethers |
| WO2007047397A2 (en) | 2005-10-13 | 2007-04-26 | Smithkline Beecham Corporation | Phenol ethers as modulators of the opioid receptors |
| US20100048713A1 (en) * | 2006-01-06 | 2010-02-25 | Aarhus Universitet | Compounds acting on the serotonin transporter |
| AU2007265240A1 (en) * | 2006-06-29 | 2008-01-03 | Janssen Pharmaceutica N.V. | Substituted aminomethyl benzamide compounds |
| US7767666B2 (en) | 2006-06-29 | 2010-08-03 | Janssen Pharmaceutica Nv | Butyl and butynyl benzyl amine compounds |
| US7479493B2 (en) | 2006-06-29 | 2009-01-20 | Janssen Pharmaceutica N.V. | Substituted benzyl amine compounds |
| US8642583B2 (en) | 2008-10-30 | 2014-02-04 | Janssen Pharmaceutica Nv | Serotonin receptor modulators |
| WO2010059390A1 (en) | 2008-10-30 | 2010-05-27 | Janssen Pharmaceutica Nv | Modulators of serotonin receptor |
| KR101043200B1 (ko) * | 2010-11-08 | 2011-06-21 | 성시민 | 호흡용 공기탱크의 공기 충전장치 |
| US9092242B2 (en) | 2011-01-27 | 2015-07-28 | Hewlett-Packard Development Company, L.P. | Computing device to connect to a portable device |
| WO2020179859A1 (ja) | 2019-03-06 | 2020-09-10 | 第一三共株式会社 | ピロロピラゾール誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA923283B (en) * | 1991-05-29 | 1993-01-27 | Akzo Nv | Phenoxyphenyl derivatives |
| EP0714391A1 (en) * | 1993-08-19 | 1996-06-05 | Warner-Lambert Company | Substituted 2(5h)furanone, 2(5h)thiophenone and 2(5h)pyrrolone derivatives, their preparation and their use as endothelin antagonists |
| CZ293595A3 (cs) * | 1995-11-09 | 1999-12-15 | Farmak A. S. | Deriváty N,N-dimethyl-2-(arylthio)benzylaminu, jejich soli, způsoby jejich přípravy a jejich použití v léčivých přípravcích |
| WO1999047497A2 (en) * | 1998-03-13 | 1999-09-23 | Merck Frosst Canada & Co. | Carboxylic acids and acylsulfonamides, compositions containing such compounds and methods of treatment |
| AU763884B2 (en) * | 1999-02-23 | 2003-07-31 | Pfizer Products Inc. | Monoamine reuptake inhibitors for treatment of CNS disorders |
| GB0007884D0 (en) * | 2000-03-31 | 2000-05-17 | Pfizer Ltd | Diphenyl ether compounds useful in therapy |
-
2001
- 2001-08-22 JP JP2002523451A patent/JP2004507523A/ja active Pending
- 2001-08-22 HU HU0303385A patent/HUP0303385A2/hu unknown
- 2001-08-22 EE EEP200300084A patent/EE200300084A/xx unknown
- 2001-08-22 OA OA1200300056A patent/OA12372A/en unknown
- 2001-08-22 AP APAP/P/2001/002265A patent/AP2001002265A0/en unknown
- 2001-08-22 MX MXPA03001848A patent/MXPA03001848A/es active IP Right Grant
- 2001-08-22 BR BR0113610-0A patent/BR0113610A/pt not_active IP Right Cessation
- 2001-08-22 SK SK201-2003A patent/SK2012003A3/sk unknown
- 2001-08-22 NZ NZ523951A patent/NZ523951A/en unknown
- 2001-08-22 CA CA002420969A patent/CA2420969A1/en not_active Abandoned
- 2001-08-22 DZ DZ013414A patent/DZ3414A1/fr active
- 2001-08-22 CZ CZ2003467A patent/CZ2003467A3/cs unknown
- 2001-08-22 IL IL15434301A patent/IL154343A0/xx unknown
- 2001-08-22 EA EA200300206A patent/EA200300206A1/ru unknown
- 2001-08-22 HR HR20030141A patent/HRP20030141A2/hr not_active Application Discontinuation
- 2001-08-22 AU AU2001278650A patent/AU2001278650A1/en not_active Abandoned
- 2001-08-22 KR KR10-2003-7003011A patent/KR20030029889A/ko not_active Ceased
- 2001-08-22 PL PL36074301A patent/PL360743A1/xx not_active Application Discontinuation
- 2001-08-22 CN CN01814846A patent/CN1449380A/zh active Pending
- 2001-08-22 EP EP01956734A patent/EP1313701A1/en not_active Withdrawn
- 2001-08-22 WO PCT/IB2001/001521 patent/WO2002018333A1/en not_active Ceased
- 2001-08-24 PA PA20018526701A patent/PA8526701A1/es unknown
- 2001-08-28 PE PE2001000862A patent/PE20020346A1/es not_active Application Discontinuation
- 2001-08-28 HN HN2001000191A patent/HN2001000191A/es unknown
- 2001-08-29 AR ARP010104114A patent/AR031867A1/es unknown
- 2001-08-29 DO DO2001000242A patent/DOP2001000242A/es unknown
- 2001-08-30 TN TNTNSN01131A patent/TNSN01131A1/fr unknown
- 2001-08-31 UY UY26924A patent/UY26924A1/es not_active Application Discontinuation
-
2003
- 2003-01-30 IS IS6704A patent/IS6704A/is unknown
- 2003-02-07 BG BG107544A patent/BG107544A/bg unknown
- 2003-02-21 MA MA27049A patent/MA26945A1/fr unknown
- 2003-02-24 NO NO20030842A patent/NO20030842L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL154343A0 (en) | 2003-09-17 |
| PE20020346A1 (es) | 2002-05-08 |
| WO2002018333A1 (en) | 2002-03-07 |
| DZ3414A1 (fr) | 2002-03-07 |
| HRP20030141A2 (en) | 2003-04-30 |
| MA26945A1 (fr) | 2004-12-20 |
| CN1449380A (zh) | 2003-10-15 |
| EE200300084A (et) | 2005-02-15 |
| JP2004507523A (ja) | 2004-03-11 |
| UY26924A1 (es) | 2002-03-22 |
| AR031867A1 (es) | 2003-10-08 |
| AU2001278650A1 (en) | 2002-03-13 |
| PA8526701A1 (es) | 2003-07-28 |
| NO20030842L (no) | 2003-04-28 |
| SK2012003A3 (en) | 2004-06-08 |
| KR20030029889A (ko) | 2003-04-16 |
| HUP0303385A2 (hu) | 2004-03-01 |
| MXPA03001848A (es) | 2003-06-04 |
| NZ523951A (en) | 2004-09-24 |
| IS6704A (is) | 2003-01-30 |
| BR0113610A (pt) | 2003-06-24 |
| CZ2003467A3 (cs) | 2004-04-14 |
| DOP2001000242A (es) | 2002-05-15 |
| HN2001000191A (es) | 2002-03-11 |
| NO20030842D0 (no) | 2003-02-24 |
| OA12372A (en) | 2006-04-17 |
| BG107544A (bg) | 2003-10-31 |
| CA2420969A1 (en) | 2002-03-07 |
| TNSN01131A1 (fr) | 2005-11-10 |
| PL360743A1 (en) | 2004-09-20 |
| EP1313701A1 (en) | 2003-05-28 |
| AP2001002265A0 (en) | 2001-09-30 |
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