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EA200000946A1 - CRYSTAL FORM OF PAROXETIN - Google Patents

CRYSTAL FORM OF PAROXETIN

Info

Publication number
EA200000946A1
EA200000946A1 EA200000946A EA200000946A EA200000946A1 EA 200000946 A1 EA200000946 A1 EA 200000946A1 EA 200000946 A EA200000946 A EA 200000946A EA 200000946 A EA200000946 A EA 200000946A EA 200000946 A1 EA200000946 A1 EA 200000946A1
Authority
EA
Eurasian Patent Office
Prior art keywords
paroxetin
crystal form
paroxetine
depression
therapy
Prior art date
Application number
EA200000946A
Other languages
Russian (ru)
Inventor
Эндрю Симон Крэйг
Нил Уорд
Уилсон Макилвэйн
Original Assignee
Смитклайн Бичам Плс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9805581.7A external-priority patent/GB9805581D0/en
Priority claimed from GBGB9813054.5A external-priority patent/GB9813054D0/en
Priority claimed from GBGB9817115.0A external-priority patent/GB9817115D0/en
Application filed by Смитклайн Бичам Плс filed Critical Смитклайн Бичам Плс
Publication of EA200000946A1 publication Critical patent/EA200000946A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к чистому, не содержащему растворителя, например, кристаллическому свободному основанию пароксетина и его применению в терапии для лечения депрессии.Международная заявка была опубликована вместе с отчетом о международном поиске.The present invention relates to a pure, solvent-free, for example, paroxetine crystalline free base and its use in therapy for the treatment of depression. The international application was published along with an international search report.

EA200000946A 1998-03-16 1999-03-16 CRYSTAL FORM OF PAROXETIN EA200000946A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9805581.7A GB9805581D0 (en) 1998-03-16 1998-03-16 Novel compounds
GBGB9813054.5A GB9813054D0 (en) 1998-06-17 1998-06-17 Novel compounds
GBGB9817115.0A GB9817115D0 (en) 1998-08-06 1998-08-06 Novel compounds
PCT/GB1999/000793 WO1999047519A1 (en) 1998-03-16 1999-03-16 Crystalline form of paroxetine

Publications (1)

Publication Number Publication Date
EA200000946A1 true EA200000946A1 (en) 2001-02-26

Family

ID=27269245

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200000946A EA200000946A1 (en) 1998-03-16 1999-03-16 CRYSTAL FORM OF PAROXETIN

Country Status (18)

Country Link
EP (1) EP1064282A1 (en)
JP (1) JP2002506865A (en)
KR (1) KR20010041947A (en)
CN (1) CN1300286A (en)
AP (1) AP2000001907A0 (en)
AU (1) AU2847199A (en)
BG (1) BG104839A (en)
BR (1) BR9908825A (en)
CA (1) CA2323896A1 (en)
EA (1) EA200000946A1 (en)
HU (1) HUP0101215A3 (en)
ID (1) ID27596A (en)
IL (1) IL138390A0 (en)
NO (1) NO20004583L (en)
PL (1) PL342931A1 (en)
SK (1) SK13622000A3 (en)
TR (1) TR200002675T2 (en)
WO (1) WO1999047519A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH689805A8 (en) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Paroxetine methanesulfonate, process for its preparation and pharmaceutical compositions containing it.
GB9919052D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel compound composition and process
US20080033050A1 (en) * 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
ES2058061T3 (en) * 1985-10-25 1994-11-01 Beecham Group Plc DERIVED FROM PIPERIDINE, ITS PREPARATION AND ITS USE AS A MEDICINAL PRODUCT.
SK283608B6 (en) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Anhydrous paroxetine hydrochloride, process for its preparation and use

Also Published As

Publication number Publication date
CN1300286A (en) 2001-06-20
JP2002506865A (en) 2002-03-05
TR200002675T2 (en) 2000-12-21
NO20004583L (en) 2000-09-15
BR9908825A (en) 2000-11-21
ID27596A (en) 2001-04-12
HUP0101215A3 (en) 2002-05-28
BG104839A (en) 2001-09-28
IL138390A0 (en) 2001-10-31
SK13622000A3 (en) 2001-03-12
AU2847199A (en) 1999-10-11
WO1999047519A1 (en) 1999-09-23
HUP0101215A2 (en) 2002-04-29
KR20010041947A (en) 2001-05-25
PL342931A1 (en) 2001-07-16
NO20004583D0 (en) 2000-09-14
AP2000001907A0 (en) 2000-09-30
CA2323896A1 (en) 1999-09-23
EP1064282A1 (en) 2001-01-03

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