EA000877B1 - Способ получения ингибиторов фосфодиэстеразы iv - Google Patents

Способ получения ингибиторов фосфодиэстеразы iv Download PDF

Info

Publication number: EA000877B1
Authority: EA; Eurasian Patent Office
Prior art keywords: alkenyl; alkyl; phenyl; compound; znmgbr
Prior art date: 1996-04-17

Application number

EA199800931A

Other languages

English (en)

Russian (ru)

Other versions

EA199800931A1 (ru

Inventor

Иоаннис Хоупис

Одри Молина

Ральф П. Волант

Original Assignee

Мерк Энд Ко., Инк.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-17

Filing date

1997-04-14

Publication date

2000-06-26

1996-06-10 Priority claimed from GBGB9612083.7A external-priority patent/GB9612083D0/en

1997-04-14 Application filed by Мерк Энд Ко., Инк. filed Critical Мерк Энд Ко., Инк.

1999-04-29 Publication of EA199800931A1 publication Critical patent/EA199800931A1/ru

2000-06-26 Publication of EA000877B1 publication Critical patent/EA000877B1/ru

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
- C07D213/34—Sulfur atoms to which a second hetero atom is attached
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EA199800931A 1996-04-17 1997-04-14 Способ получения ингибиторов фосфодиэстеразы iv EA000877B1 (ru)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1568796P	1996-04-17	1996-04-17
GBGB9612083.7A GB9612083D0 (en)	1996-06-10	1996-06-10	Method of preparing phosphodiesterase IV inhibitors
PCT/US1997/006131 WO1997038976A1 (en)	1996-04-17	1997-04-14	Method of preparing phosphodiesterase iv inhibitors

Publications (2)

Publication Number	Publication Date
EA199800931A1 EA199800931A1 (ru)	1999-04-29
EA000877B1 true EA000877B1 (ru)	2000-06-26

Family

ID=26309476

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EA199800931A EA000877B1 (ru)	1996-04-17	1997-04-14	Способ получения ингибиторов фосфодиэстеразы iv

Country Status (10)

Country	Link
EP (1)	EP0898564A1 (pt)
CN (1)	CN1216532A (pt)
AR (1)	AR006550A1 (pt)
AU (1)	AU2459297A (pt)
BR (1)	BR9708684A (pt)
CZ (1)	CZ333298A3 (pt)
EA (1)	EA000877B1 (pt)
SK (1)	SK143198A3 (pt)
TW (1)	TW426669B (pt)
WO (1)	WO1997038976A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW508353B (en) *	1996-09-17	2002-11-01	Merck & Co Inc	Method of preparing phosphodiesterase IV inhibitors
WO1998012178A1 (en) *	1996-09-17	1998-03-26	Merck & Co., Inc.	Method of preparing phosphodiesterase iv inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW263495B (pt) *	1992-12-23	1995-11-21	Celltech Ltd
GB9326173D0 (en) *	1993-12-22	1994-02-23	Celltech Ltd	Chemical compounds and process

1997
- 1997-04-07 AR ARP970101372A patent/AR006550A1/es unknown
- 1997-04-14 BR BR9708684A patent/BR9708684A/pt unknown
- 1997-04-14 CZ CZ983332A patent/CZ333298A3/cs unknown
- 1997-04-14 AU AU24592/97A patent/AU2459297A/en not_active Abandoned
- 1997-04-14 EP EP97920379A patent/EP0898564A1/en not_active Withdrawn
- 1997-04-14 CN CN97193932A patent/CN1216532A/zh active Pending
- 1997-04-14 WO PCT/US1997/006131 patent/WO1997038976A1/en not_active Ceased
- 1997-04-14 EA EA199800931A patent/EA000877B1/ru not_active IP Right Cessation
- 1997-04-14 SK SK1431-98A patent/SK143198A3/sk unknown
- 1997-04-15 TW TW086104869A patent/TW426669B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1997038976A1 (en)	1997-10-23
SK143198A3 (en)	1999-06-11
TW426669B (en)	2001-03-21
AU2459297A (en)	1997-11-07
CZ333298A3 (cs)	1999-03-17
CN1216532A (zh)	1999-05-12
EA199800931A1 (ru)	1999-04-29
BR9708684A (pt)	1999-08-03
EP0898564A1 (en)	1999-03-03
AR006550A1 (es)	1999-09-08

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Legal Events

Date	Code	Title	Description
2002-04-25	MM4A	Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)	Designated state(s): AM AZ BY KZ KG MD TJ TM
2004-02-26	MM4A	Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)	Designated state(s): RU