EA005236B1 - Композиция для лечения и/или предупреждения нарушений, приводящих к аномальному кровотечению, и способ лечения таких нарушений (варианты) - Google Patents

Композиция для лечения и/или предупреждения нарушений, приводящих к аномальному кровотечению, и способ лечения таких нарушений (варианты) Download PDF

Info

Publication number: EA005236B1
Authority: EA; Eurasian Patent Office
Prior art keywords: agent; factor; antibody; composition; factor viii
Prior art date: 1998-09-21

Application number

EA200100385A

Other languages

English (en)

Russian (ru)

Other versions

EA200100385A1 (ru

Inventor

Гэри С. Грэй

Джиахуа Киан

Мэри Коллинс

Леон У. Хойэр

Original Assignee

ДЖИНЕТИКС ИНСТИТЬЮТ, эЛэЛСи

Эмерикэн Ред Кросс

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-21

Filing date

1999-09-21

Publication date

2004-12-30

1999-09-21 Application filed by ДЖИНЕТИКС ИНСТИТЬЮТ, эЛэЛСи, Эмерикэн Ред Кросс filed Critical ДЖИНЕТИКС ИНСТИТЬЮТ, эЛэЛСи

2001-10-22 Publication of EA200100385A1 publication Critical patent/EA200100385A1/ru

2004-12-30 Publication of EA005236B1 publication Critical patent/EA005236B1/ru

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210000001236 prokaryotic cell Anatomy 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
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230000017854 proteolysis Effects 0.000 description 1
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150000003244 quercetin derivatives Chemical class 0.000 description 1
ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Hematology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Microbiology (AREA)
Mycology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

EA200100385A 1998-09-21 1999-09-21 Композиция для лечения и/или предупреждения нарушений, приводящих к аномальному кровотечению, и способ лечения таких нарушений (варианты) EA005236B1 (ru)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US15817898A	1998-09-21	1998-09-21
PCT/US1999/021991 WO2000016801A1 (en)	1998-09-21	1999-09-21	Methods of downmodulating the immune response to therapeutic proteins

Publications (2)

Publication Number	Publication Date
EA200100385A1 EA200100385A1 (ru)	2001-10-22
EA005236B1 true EA005236B1 (ru)	2004-12-30

Family

ID=22566971

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EA200100385A EA005236B1 (ru)	1998-09-21	1999-09-21	Композиция для лечения и/или предупреждения нарушений, приводящих к аномальному кровотечению, и способ лечения таких нарушений (варианты)

Country Status (21)

Country	Link
EP (1)	EP1115423A1 (lt)
JP (1)	JP2002526455A (lt)
KR (1)	KR20010085830A (lt)
CN (1)	CN1331602A (lt)
AU (1)	AU761206B2 (lt)
BR (1)	BR9913991A (lt)
CA (1)	CA2343916A1 (lt)
CZ (1)	CZ20011021A3 (lt)
EA (1)	EA005236B1 (lt)
HK (1)	HK1039059A1 (lt)
HU (1)	HUP0103960A3 (lt)
IL (1)	IL142069A0 (lt)
LT (1)	LT4920B (lt)
LV (1)	LV12768B (lt)
MX (1)	MXPA01002898A (lt)
NO (1)	NO20011412L (lt)
NZ (1)	NZ511034A (lt)
PL (1)	PL346796A1 (lt)
SI (1)	SI20626A (lt)
WO (1)	WO2000016801A1 (lt)
ZA (1)	ZA200103156B (lt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5397703A (en)	1992-07-09	1995-03-14	Cetus Oncology Corporation	Method for generation of antibodies to cell surface molecules
AU2001261735B2 (en) *	2000-05-19	2006-09-21	The Center For Blood Research, Inc.	Methods for diagnosing and treating hemostatic disorders by modulating p-selectin activity
EP1636579A4 (en) *	2003-06-10	2011-10-05	Smiths Detection Inc	SENSOR ASSEMBLY
GB201508024D0 (en) *	2015-05-11	2015-06-24	Haemostatix Ltd	Haemostatic compositions

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US5171569A (en)	1985-03-15	1992-12-15	National Research Development Corporation	Factor IX preparations uncontaminated by plasma components or pox virus
MX9203440A (es)	1985-04-12	1992-07-01	Genetics Inst	Proteinas procoagulantes novedosas.
US5422260A (en)	1986-05-29	1995-06-06	Genetics Institute, Inc. -Legal Affairs	Human factor VIII:c muteins
US4994371A (en)	1987-08-28	1991-02-19	Davie Earl W	DNA preparation of Christmas factor and use of DNA sequences
FR2657884B1 (fr)	1990-02-05	1994-09-02	Tm Innovation	Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
US5661008A (en)	1991-03-15	1997-08-26	Kabi Pharmacia Ab	Recombinant human factor VIII derivatives
DE122007000078I2 (de)	1991-06-27	2011-01-13	Bristol Myers Squibb Co	CTL4A-Rezeptor, ihn enthaltenden Fusionsproteine und deren Verwendung
US5770197A (en)	1991-06-27	1998-06-23	Bristol-Myers Squibb Company	Methods for regulating the immune response using B7 binding molecules and IL4-binding molecules
WO1993009804A1 (en)	1991-11-18	1993-05-27	The Scripps Research Institute	Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation
US5744446A (en)	1992-04-07	1998-04-28	Emory University	Hybrid human/animal factor VIII
US5364771A (en)	1992-04-07	1994-11-15	Emory University	Hybrid human/porcine factor VIII
US5663060A (en)	1992-04-07	1997-09-02	Emory University	Hybrid human/animal factor VIII
US5621039A (en)	1993-06-08	1997-04-15	Hallahan; Terrence W.	Factor IX- polymeric conjugates
EP0776217A1 (en) *	1994-08-19	1997-06-04	Novo Nordisk A/S	A method of treating a patient with a biologically active compound
CA2200869A1 (en) *	1994-10-19	1996-05-02	Bruce C. Trapnell	Gene therapy involving concurrent and repeated administration of adenoviruses and immunosuppressive agents
US5714583A (en)	1995-06-07	1998-02-03	Genetics Institute, Inc.	Factor IX purification methods
WO1997034633A1 (en) *	1996-03-20	1997-09-25	Bristol-Myers Squibb Company	Methods for inhibiting an immune response by blocking the gp39/cd40 and ctla4/cd28/b7 pathways and compositions for use therewith
CZ244399A3 (cs) *	1997-01-10	1999-10-13	Biogen, Inc.	Použití sloučeniny anti-CD40L pro výrobu léku pro léčení imunologických onemocnění
IL133305A0 (en) *	1997-06-20	2001-04-30	Biogen Inc	Use of a cd40:cd154 binding interruptor for treating protein inhibitor syndrome
US8112896B2 (en)	2009-11-06	2012-02-14	Hexagon Metrology Ab	Articulated arm

1999
- 1999-09-21 CA CA002343916A patent/CA2343916A1/en not_active Abandoned
- 1999-09-21 IL IL14206999A patent/IL142069A0/xx unknown
- 1999-09-21 PL PL99346796A patent/PL346796A1/xx not_active Application Discontinuation
- 1999-09-21 BR BR9913991-0A patent/BR9913991A/pt not_active IP Right Cessation
- 1999-09-21 HU HU0103960A patent/HUP0103960A3/hu unknown
- 1999-09-21 MX MXPA01002898A patent/MXPA01002898A/es unknown
- 1999-09-21 WO PCT/US1999/021991 patent/WO2000016801A1/en not_active Ceased
- 1999-09-21 EP EP99969339A patent/EP1115423A1/en not_active Withdrawn
- 1999-09-21 CN CN99813510A patent/CN1331602A/zh active Pending
- 1999-09-21 HK HK02100157.7A patent/HK1039059A1/zh unknown
- 1999-09-21 SI SI9920084A patent/SI20626A/sl not_active IP Right Cessation
- 1999-09-21 AU AU60578/99A patent/AU761206B2/en not_active Ceased
- 1999-09-21 NZ NZ511034A patent/NZ511034A/xx unknown
- 1999-09-21 KR KR1020017003611A patent/KR20010085830A/ko not_active Withdrawn
- 1999-09-21 CZ CZ20011021A patent/CZ20011021A3/cs unknown
- 1999-09-21 EA EA200100385A patent/EA005236B1/ru not_active IP Right Cessation
- 1999-09-21 JP JP2000573762A patent/JP2002526455A/ja not_active Withdrawn
2001
- 2001-03-20 NO NO20011412A patent/NO20011412L/no not_active Application Discontinuation
- 2001-04-18 ZA ZA200103156A patent/ZA200103156B/xx unknown
- 2001-04-20 LV LVP-01-62A patent/LV12768B/lv unknown
- 2001-04-20 LT LT2001045A patent/LT4920B/lt not_active IP Right Cessation

Also Published As

Publication number	Publication date
EA200100385A1 (ru)	2001-10-22
HK1039059A1 (zh)	2002-04-12
CA2343916A1 (en)	2000-03-30
MXPA01002898A (es)	2002-06-04
EP1115423A1 (en)	2001-07-18
HUP0103960A2 (hu)	2002-02-28
SI20626A (sl)	2002-02-28
LT2001045A (lt)	2002-01-25
LV12768B (lv)	2002-06-20
LT4920B (lt)	2002-06-25
IL142069A0 (en)	2002-03-10
BR9913991A (pt)	2001-07-03
ZA200103156B (en)	2002-07-18
AU6057899A (en)	2000-04-10
KR20010085830A (ko)	2001-09-07
CZ20011021A3 (cs)	2001-10-17
JP2002526455A (ja)	2002-08-20
NO20011412L (no)	2001-05-16
LV12768A (en)	2001-12-20
PL346796A1 (en)	2002-02-25
AU761206B2 (en)	2003-05-29
CN1331602A (zh)	2002-01-16
NO20011412D0 (no)	2001-03-20
NZ511034A (en)	2004-03-26
HUP0103960A3 (en)	2003-09-29
WO2000016801A9 (en)	2000-10-26
WO2000016801A1 (en)	2000-03-30

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JP4052524B2 (ja)	2008-02-27	Ｔ細胞における抗原特異性アポトーシスの誘導のためのリガンド
Shenoy-Scaria et al.	1992	Signal transduction through decay-accelerating factor. Interaction of glycosyl-phosphatidylinositol anchor and protein tyrosine kinases p56lck and p59fyn 1
KR100257466B1 (ko)	2000-07-01	Lag-3의 가용성 폴리펩타이드 절편 및 생산 방법 치료 조성물, 항-이디오타입 항체
Benjamin et al.	1988	Mechanisms of monoclonal antibody‐facilitated tolerance induction: a possible role for the CD4 (L3T4) and CD11a (LFA‐1) molecules in self‐non‐self discrimination
JP2003520828A (ja)	2003-07-08	Ｃｔｌａ４（ｃｄ１５２）に対する抗体、これを含む結合体、およびその使用
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EP1755660A2 (en)	2007-02-28	Method for enhancing or inhibiting insulin-like growth factor-i
AU2004240180B2 (en)	2007-08-09	Methods of prolonged suppression of humoral immunity
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EA005236B1 (ru)	2004-12-30	Композиция для лечения и/или предупреждения нарушений, приводящих к аномальному кровотечению, и способ лечения таких нарушений (варианты)
US20030161827A1 (en)	2003-08-28	Therapies that improve graft survival
US20070092506A1 (en)	2007-04-26	Use of rapamycin and agents that inhibit B7 activity in immunomodulation
Greenwood et al.	2003	Identification of T-cell epitopes in clotting factor IX and lack of tolerance in inbred mice
JPH07501524A (ja)	1995-02-16	ｕＰＡ−Ｒの検出・分離方法及びｕＰＡのｕＰＡ−Ｒへの結合阻止方法
WO1997017360A2 (en)	1997-05-15	Methods for modulating t cell responses by manipulating a common cytokine receptor gamma chain
WO1998016548A1 (en)	1998-04-23	Thrombin receptor peptides and uses thereof
US20020071839A1 (en)	2002-06-13	Use of a combination of agents that modulate B7 activity in inhibiting intestinal allograft rejection
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Cobbold	1988	Cambridge zyxwvutsrqponmlkjihgfedcb

Legal Events

Date	Code	Title	Description
2003-12-25	PD1A	Registration of transfer to a eurasian application by order of succession in title
2006-06-30	MM4A	Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)	Designated state(s): AM AZ BY KZ KG MD TJ TM RU