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DK8892D0 - Humant proteingen - Google Patents

Humant proteingen

Info

Publication number
DK8892D0
DK8892D0 DK9288A DK8892A DK8892D0 DK 8892 D0 DK8892 D0 DK 8892D0 DK 9288 A DK9288 A DK 9288A DK 8892 A DK8892 A DK 8892A DK 8892 D0 DK8892 D0 DK 8892D0
Authority
DK
Denmark
Prior art keywords
mammal
human
expression system
dna sequence
casein
Prior art date
Application number
DK9288A
Other languages
English (en)
Inventor
Lennart Hansson
Mats Stroemqvist
Sven Bergstroem
Olle Hernell
Jan Toernell
Original Assignee
Symbicom Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom Ab filed Critical Symbicom Ab
Priority to DK9288A priority Critical patent/DK8892D0/da
Publication of DK8892D0 publication Critical patent/DK8892D0/da
Priority to JP51286793A priority patent/JP3467272B2/ja
Priority to ES93902110T priority patent/ES2188592T3/es
Priority to US08/256,799 priority patent/US6222094B1/en
Priority to CA002128110A priority patent/CA2128110A1/en
Priority to EP93902110A priority patent/EP0625197B1/en
Priority to DK93902110T priority patent/DK0625197T3/da
Priority to DE69332537T priority patent/DE69332537T2/de
Priority to PCT/DK1993/000024 priority patent/WO1993015196A1/en
Priority to AT93902110T priority patent/ATE229071T1/de
Priority to AU33464/93A priority patent/AU3346493A/en
Priority to PT93902110T priority patent/PT625197E/pt
Priority to US08/462,437 priority patent/US6232094B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/101—Bovine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Dairy Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK9288A 1992-01-23 1992-01-23 Humant proteingen DK8892D0 (da)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DK9288A DK8892D0 (da) 1992-01-23 1992-01-23 Humant proteingen
PT93902110T PT625197E (pt) 1992-01-23 1993-01-25 Adn que codifica a k-cseina, processo para a obtencao da proteina e sua utilizacao
CA002128110A CA2128110A1 (en) 1992-01-23 1993-01-25 Dna encoding kappa-casein, process for obtaining the protein and use thereof
ES93902110T ES2188592T3 (es) 1992-01-23 1993-01-25 Adn que codifica para la kappa-caseina, proceso para la obtencion de la proteina y uso de la misma.
US08/256,799 US6222094B1 (en) 1992-01-23 1993-01-25 Transgenic non-human mammal expressing the DNA sequence encoding kappa casein mammary gland and milk
JP51286793A JP3467272B2 (ja) 1992-01-23 1993-01-25 κ−カゼインをコードするＤＮＡ，そのタンパク質を得る方法および用途
EP93902110A EP0625197B1 (en) 1992-01-23 1993-01-25 Dna encoding kappa-casein, process for obtaining the protein and use thereof
DK93902110T DK0625197T3 (da) 1992-01-23 1993-01-25 DNA, der koder for k-kasein, fremgangsmåde til opnåelse af proteinet og anvendelse af dette
DE69332537T DE69332537T2 (de) 1992-01-23 1993-01-25 Für kappa-casein kodierende dna, verfahren zur gewinnung des proteins und seine verwendung
PCT/DK1993/000024 WO1993015196A1 (en) 1992-01-23 1993-01-25 Dna encoding kappa-casein, process for obtaining the protein and use thereof
AT93902110T ATE229071T1 (de) 1992-01-23 1993-01-25 Für kappa-casein kodierende dna, verfahren zur gewinnung des proteins und seine verwendung
AU33464/93A AU3346493A (en) 1992-01-23 1993-01-25 DNA encoding kappa-casein, process for obtaining the protein and use thereof
US08/462,437 US6232094B1 (en) 1992-01-23 1995-06-05 DNA encoding human κ casein and process for obtaining the protein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK9288A DK8892D0 (da) 1992-01-23 1992-01-23 Humant proteingen

Publications (1)

Publication Number Publication Date
DK8892D0 true DK8892D0 (da) 1992-01-23

Family

ID=8089602

Family Applications (2)

Application Number Title Priority Date Filing Date
DK9288A DK8892D0 (da) 1992-01-23 1992-01-23 Humant proteingen
DK93902110T DK0625197T3 (da) 1992-01-23 1993-01-25 DNA, der koder for k-kasein, fremgangsmåde til opnåelse af proteinet og anvendelse af dette

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK93902110T DK0625197T3 (da) 1992-01-23 1993-01-25 DNA, der koder for k-kasein, fremgangsmåde til opnåelse af proteinet og anvendelse af dette

Country Status (11)

Country Link
US (2) US6222094B1 (da)
EP (1) EP0625197B1 (da)
JP (1) JP3467272B2 (da)
AT (1) ATE229071T1 (da)
AU (1) AU3346493A (da)
CA (1) CA2128110A1 (da)
DE (1) DE69332537T2 (da)
DK (2) DK8892D0 (da)
ES (1) ES2188592T3 (da)
PT (1) PT625197E (da)
WO (1) WO1993015196A1 (da)

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EA023475B1 (ru) * 2012-10-08 2016-06-30 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pFK4, ОБЕСПЕЧИВАЮЩАЯ СИНТЕЗ РЕКОМБИНАНТНОГО ПЕПТИДА RL4, ЯВЛЯЮЩЕГОСЯ АНАЛОГОМ ФРАГМЕНТА КАППА-КАЗЕИНА ЧЕЛОВЕКА, РЕКОМБИНАНТНЫЙ ШТАММ БАКТЕРИЙ ESCHERICHIA COLI XL1-BLUE/pFK4 И РЕКОМБИНАНТНЫЙ ПЕПТИД RL4 - АНАЛОГ ФРАГМЕНТА КАППА-КАЗЕИНА ЧЕЛОВЕКА, ОБЛАДАЮЩИЙ АПОПТОТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К РАКОВЫМ КЛЕТКАМ
EA023387B1 (ru) * 2012-10-08 2016-05-31 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pFK3, ОБЕСПЕЧИВАЮЩАЯ СИНТЕЗ РЕКОМБИНАНТНОГО ПЕПТИДА RL3, ЯВЛЯЮЩЕГОСЯ АНАЛОГОМ ФРАГМЕНТА КАППА-КАЗЕИНА ЧЕЛОВЕКА, РЕКОМБИНАНТНЫЙ ШТАММ БАКТЕРИЙ ESCHERICHIA COLI XL1-Blue/pFK3 И РЕКОМБИНАНТНЫЙ ПЕПТИД RL3 - АНАЛОГ ФРАГМЕНТА КАППА-КАЗЕИНА ЧЕЛОВЕКА, ОБЛАДАЮЩИЙ АПОПТОТИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К РАКОВЫМ КЛЕТКАМ
EP3182842A1 (en) 2014-08-21 2017-06-28 Perfect Day, Inc. Compositions comprising a casein and methods of producing the same
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EP3970501A1 (en) 2020-09-18 2022-03-23 Baio Method for producing cheese substitutes
CA3196018A1 (en) 2020-09-18 2022-03-24 Standing Ovation Method for producing cheese substitutes
WO2022072718A1 (en) 2020-09-30 2022-04-07 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
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CN115851468A (zh) * 2022-07-18 2023-03-28 江南大学 一种生产人酪蛋白巨肽的重组毕赤酵母及其应用
EP4328240A1 (en) * 2022-08-25 2024-02-28 Real Deal Milk S.L. Recombinant protein production
WO2024102436A1 (en) * 2022-11-10 2024-05-16 The Johns Hopkins University System for modulating receptor tyrosine kinase signaling and methods of use thereof
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WO2025114239A1 (en) 2023-11-27 2025-06-05 Standing Ovation Method for improving the texture of a dairy-substitute product
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Also Published As

Publication number Publication date
ES2188592T3 (es) 2003-07-01
WO1993015196A1 (en) 1993-08-05
JPH07503136A (ja) 1995-04-06
DE69332537D1 (de) 2003-01-16
PT625197E (pt) 2003-04-30
DK0625197T3 (da) 2003-03-24
EP0625197B1 (en) 2002-12-04
DE69332537T2 (de) 2003-09-04
JP3467272B2 (ja) 2003-11-17
CA2128110A1 (en) 1993-08-05
ATE229071T1 (de) 2002-12-15
US6232094B1 (en) 2001-05-15
EP0625197A1 (en) 1994-11-23
US6222094B1 (en) 2001-04-24
AU3346493A (en) 1993-09-01

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