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DK716188D0 - Quinoxalinforbindelser, deres fremstilling og anvendelse - Google Patents

Quinoxalinforbindelser, deres fremstilling og anvendelse

Info

Publication number
DK716188D0
DK716188D0 DK716188A DK716188A DK716188D0 DK 716188 D0 DK716188 D0 DK 716188D0 DK 716188 A DK716188 A DK 716188A DK 716188 A DK716188 A DK 716188A DK 716188 D0 DK716188 D0 DK 716188D0
Authority
DK
Denmark
Prior art keywords
hydrogen
compounds
halogen
so2nr
so2r
Prior art date
Application number
DK716188A
Other languages
English (en)
Inventor
Tage Honore
Poul Jacobsen
Flemming Elmelund Nielsen
Lars Naerum
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of DK716188D0 publication Critical patent/DK716188D0/da
Priority to DK716188A priority Critical patent/DK716188D0/da
Application filed by Ferrosan As filed Critical Ferrosan As
Priority to IE375089A priority patent/IE65171B1/en
Priority to IL9246489A priority patent/IL92464A/en
Priority to CA002004077A priority patent/CA2004077A1/en
Priority to ES89121912T priority patent/ES2057076T3/es
Priority to AT89121912T priority patent/ATE108182T1/de
Priority to EP89121912A priority patent/EP0374534B1/en
Priority to DE68916626T priority patent/DE68916626T2/de
Priority to ZA899470A priority patent/ZA899470B/xx
Priority to US07/451,382 priority patent/US5081123A/en
Priority to DK639789A priority patent/DK165293C/da
Priority to AU46874/89A priority patent/AU624885B2/en
Priority to NZ231905A priority patent/NZ231905A/xx
Priority to NO895196A priority patent/NO178662C/no
Priority to JP1329779A priority patent/JPH02221264A/ja
Priority to FI896236A priority patent/FI896236A7/fi
Priority to PT92717A priority patent/PT92717B/pt
Priority to US07/794,262 priority patent/US5153195A/en
Priority to US07/914,274 priority patent/US5308845A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Television Signal Processing For Recording (AREA)
  • Luminescent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK716188A 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse DK716188D0 (da)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DK716188A DK716188D0 (da) 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse
IE375089A IE65171B1 (en) 1988-12-22 1989-11-24 Quinoxaline compounds and their preparation and use
IL9246489A IL92464A (en) 1988-12-22 1989-11-27 Quinoxaline compounds their preparation and pharmaceutical compositions containing them
CA002004077A CA2004077A1 (en) 1988-12-22 1989-11-28 Quinoxaline compounds and their preparation and use
ES89121912T ES2057076T3 (es) 1988-12-22 1989-11-28 Compuestos de quinoxalina y su preparacion y empleo.
AT89121912T ATE108182T1 (de) 1988-12-22 1989-11-28 Chinoxalin-verbindungen, ihre herstellung und verwendung.
EP89121912A EP0374534B1 (en) 1988-12-22 1989-11-28 Quinoxaline compounds and their preparation and use
DE68916626T DE68916626T2 (de) 1988-12-22 1989-11-28 Chinoxalin-Verbindungen, ihre Herstellung und Verwendung.
ZA899470A ZA899470B (en) 1988-12-22 1989-12-12 Quinoxaline compounds and their preparation and use
US07/451,382 US5081123A (en) 1988-12-22 1989-12-15 Quinoxaline compound and their preparation and use
DK639789A DK165293C (da) 1988-12-22 1989-12-18 Quinoxalinforbindelser, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne
AU46874/89A AU624885B2 (en) 1988-12-22 1989-12-19 Substituted fused quinoxaline -2,3 (1h,4h) diones, their preparation and use
NZ231905A NZ231905A (en) 1988-12-22 1989-12-20 Substituted quinoxaline dione derivatives and pharmaceutical compositions
NO895196A NO178662C (no) 1988-12-22 1989-12-21 Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoksalinforbindelser
JP1329779A JPH02221264A (ja) 1988-12-22 1989-12-21 キノキサリン化合物、その製造方法及びその使用法
FI896236A FI896236A7 (fi) 1988-12-22 1989-12-22 Kinoksaliiniyhdisteitä ja niiden valmistus ja käyttö
PT92717A PT92717B (pt) 1988-12-22 1989-12-22 Processo de preparacao de compostos de heterociclicos derivados da quinoxalina e de composicoes farmaceuticas que os contem
US07/794,262 US5153195A (en) 1988-12-22 1991-11-15 Quinoxaline compounds and their preparation and use
US07/914,274 US5308845A (en) 1988-12-22 1992-07-15 Quinoxaline compounds and their preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK716188A DK716188D0 (da) 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK716188D0 true DK716188D0 (da) 1988-12-22

Family

ID=8149233

Family Applications (1)

Application Number Title Priority Date Filing Date
DK716188A DK716188D0 (da) 1988-12-22 1988-12-22 Quinoxalinforbindelser, deres fremstilling og anvendelse

Country Status (16)

Country Link
US (1) US5081123A (da)
EP (1) EP0374534B1 (da)
JP (1) JPH02221264A (da)
AT (1) ATE108182T1 (da)
AU (1) AU624885B2 (da)
CA (1) CA2004077A1 (da)
DE (1) DE68916626T2 (da)
DK (1) DK716188D0 (da)
ES (1) ES2057076T3 (da)
FI (1) FI896236A7 (da)
IE (1) IE65171B1 (da)
IL (1) IL92464A (da)
NO (1) NO178662C (da)
NZ (1) NZ231905A (da)
PT (1) PT92717B (da)
ZA (1) ZA899470B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308845A (en) * 1988-12-22 1994-05-03 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK69790D0 (da) * 1990-03-16 1990-03-16 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling af anvendelse
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
ATE404201T1 (de) * 1992-06-22 2008-08-15 Univ California Glycinrezeptorantagonisten und ihre verwendung
DE69313866T2 (de) * 1992-10-13 1998-03-05 Warner Lambert Co Chinoxalinderivate als eaa antagonisten
DK12293D0 (da) * 1993-02-02 1993-02-02 Novo Nordisk As Heterocykliske forbindelser og deres fremstilling og anvendelse
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
DE4340045A1 (de) * 1993-11-24 1995-06-01 Basf Ag Neue Chinoxaline und Arzneimittel daraus
US5500420A (en) * 1993-12-20 1996-03-19 Cornell Research Foundation, Inc. Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia
WO1995018616A2 (en) * 1994-01-03 1995-07-13 Acea Pharm Inc 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor
AU688459B2 (en) * 1994-04-08 1998-03-12 Shionogi & Co., Ltd. Oxopyridinylquinoxaline derivative
DE4428152A1 (de) * 1994-06-22 1996-01-04 Basf Ag Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
EP0705834A1 (de) * 1994-07-27 1996-04-10 Ciba-Geigy Ag Azaaliphatisch Überbrückte Chinoxalin-2,3-dione
EP0705835A1 (de) * 1994-09-01 1996-04-10 Ciba-Geigy Ag Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione
AU3650695A (en) * 1994-09-30 1996-04-26 Basf Aktiengesellschaft New heterocyclic substituted imidazoloquinoxalinones, their preparation and their use
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones
AU4423496A (en) 1995-03-14 1996-10-02 Warner-Lambert Company Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones
DE19521058A1 (de) * 1995-06-09 1996-12-12 Basf Ag Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
DE19624808A1 (de) 1996-06-21 1998-01-02 Basf Ag Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
US5968928A (en) * 1996-09-19 1999-10-19 Warner-Lambert Company Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof
AU156088S (en) 2003-03-28 2004-08-06 Black & Decker Inc Dust extractor
MXPA06003578A (es) * 2003-09-30 2006-08-31 Johnson & Johnson Compuestos de quinoxalina.
AU2011203039B2 (en) * 2004-02-23 2013-02-21 Trustees Of Tufts College Inhibitors of dipeptidylpeptidase IV for regulating glucose metabolism
RU2379315C2 (ru) * 2004-02-23 2010-01-20 Трастиз Оф Тафтс Колледж Ингибиторы дипептидилпептидазы iv
CN1942182B (zh) * 2004-02-23 2010-05-26 塔夫茨大学信托人 调节葡萄糖代谢的二肽基肽酶ⅳ抑制剂
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE66149B1 (en) * 1986-09-16 1995-12-13 Novo Nordisk As Quinoxaline compounds and their preparation and use
DK146787A (da) * 1987-03-23 1988-09-24 Ferrosan Heterocykliske forbindelser, deres fremstilling og anvendelse
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar

Also Published As

Publication number Publication date
DE68916626D1 (de) 1994-08-11
NO895196L (no) 1990-06-25
JPH02221264A (ja) 1990-09-04
ES2057076T3 (es) 1994-10-16
PT92717A (pt) 1990-06-29
CA2004077A1 (en) 1990-06-22
DE68916626T2 (de) 1994-10-27
IL92464A (en) 1995-07-31
NO178662B (no) 1996-01-29
US5081123A (en) 1992-01-14
ATE108182T1 (de) 1994-07-15
FI896236A0 (fi) 1989-12-22
PT92717B (pt) 1995-12-29
IE65171B1 (en) 1995-10-04
AU624885B2 (en) 1992-06-25
NO895196D0 (no) 1989-12-21
EP0374534A1 (en) 1990-06-27
AU4687489A (en) 1990-06-28
NO178662C (no) 1996-05-08
NZ231905A (en) 1991-11-26
IE893750L (en) 1990-06-22
EP0374534B1 (en) 1994-07-06
FI896236A7 (fi) 1990-06-23
ZA899470B (en) 1990-09-26
IL92464A0 (en) 1990-08-31

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Legal Events

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AHS Application shelved for other reasons than non-payment