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DK673087D0 - Benzoxazinyl- og benzothiazinylpyridazinonforbindelser - Google Patents

Benzoxazinyl- og benzothiazinylpyridazinonforbindelser

Info

Publication number
DK673087D0
DK673087D0 DK673087A DK673087A DK673087D0 DK 673087 D0 DK673087 D0 DK 673087D0 DK 673087 A DK673087 A DK 673087A DK 673087 A DK673087 A DK 673087A DK 673087 D0 DK673087 D0 DK 673087D0
Authority
DK
Denmark
Prior art keywords
benzothiazinylpyridazinon
benzoxazinyl
compounds
benzothiazinylpyridazinon compounds
Prior art date
Application number
DK673087A
Other languages
English (en)
Other versions
DK673087A (da
Inventor
Donald W Combs
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/944,316 external-priority patent/US4721784A/en
Priority claimed from US07/064,638 external-priority patent/US4766118A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of DK673087D0 publication Critical patent/DK673087D0/da
Publication of DK673087A publication Critical patent/DK673087A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/141,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/161,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK673087A 1986-12-22 1987-12-21 Benzoxazinyl- og benzothiazinylpyridazinonforbindelser DK673087A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/944,316 US4721784A (en) 1986-12-22 1986-12-22 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
US07/064,638 US4766118A (en) 1986-12-22 1987-06-22 6-benzoxazinyl- and 6-benzothiazinyl-2,3,4,5-tetrahydropyridazin-3-ones and pharmaceutical use
US12514287A 1987-12-02 1987-12-02

Publications (2)

Publication Number Publication Date
DK673087D0 true DK673087D0 (da) 1987-12-21
DK673087A DK673087A (da) 1988-06-23

Family

ID=27370654

Family Applications (1)

Application Number Title Priority Date Filing Date
DK673087A DK673087A (da) 1986-12-22 1987-12-21 Benzoxazinyl- og benzothiazinylpyridazinonforbindelser

Country Status (12)

Country Link
EP (1) EP0272914A3 (da)
KR (1) KR880007527A (da)
AU (2) AU607731B2 (da)
DK (1) DK673087A (da)
FI (1) FI86425C (da)
HU (1) HU207314B (da)
IL (1) IL84832A (da)
MY (2) MY106781A (da)
NO (1) NO173653C (da)
NZ (1) NZ222843A (da)
PH (1) PH24498A (da)
PT (1) PT86453B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3934436A1 (de) * 1989-06-01 1991-04-18 Thomae Gmbh Dr K 2-hydroxy-n-propylamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
TW224941B (da) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd
US5221742A (en) * 1990-12-21 1993-06-22 Ortho Pharmaceutical Corporation Process for the preparation of 6-(3,4-dihydro-3-oxo-1,4(2h)-benzoxazin-7-yl)-2,3,4,5-tetrahydropyridazin-3-ones
AU1493092A (en) * 1991-04-18 1992-10-22 Ortho Pharmaceutical Corporation (+) and (-) enantiomers of 5-aliphatic-6-(benzoxazinyl- or benzothiazinyl)-2,3,4,5-tetrahydropyridazin-3-ones
WO1997011060A1 (en) * 1995-09-22 1997-03-27 Sumitomo Chemical Company, Limited Pyrazin-2-one derivatives, their use, and intermediates for their production
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2562244A1 (en) 2004-04-07 2005-10-27 Takeda Pharmaceutical Company Limited Cyclic compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2218442A1 (en) 2005-11-09 2010-08-18 CombinatoRx, Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
KR102034748B1 (ko) 2011-03-01 2019-10-21 시너지 파마슈티컬즈 인코포레이티드 구아닐레이트 사이클라제 c 작용제의 제조 방법
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use
US9545446B2 (en) 2013-02-25 2017-01-17 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
WO2015021358A2 (en) 2013-08-09 2015-02-12 Dominique Charmot Compounds and methods for inhibiting phosphate transport
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (da) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
FR2588868B1 (fr) * 1985-10-21 1988-11-10 Negma Laboratoires Acyl-7 benzoxazinones et leurs derives, procede pour les obtenir et compositions pharmaceutiques les contenant
TW224941B (da) * 1989-11-08 1994-06-11 Yamanouchi Pharma Co Ltd

Also Published As

Publication number Publication date
FI86425C (fi) 1992-08-25
AU6808690A (en) 1991-04-26
FI86425B (fi) 1992-05-15
NZ222843A (en) 1989-10-27
EP0272914A2 (en) 1988-06-29
MY102280A (en) 1992-05-15
IL84832A (en) 1993-01-14
NO173653B (no) 1993-10-04
HUT48624A (en) 1989-06-28
PH24498A (en) 1990-07-18
FI875619A0 (fi) 1987-12-21
NO173653C (no) 1994-01-12
AU8293287A (en) 1988-06-23
IL84832A0 (en) 1988-06-30
EP0272914A3 (en) 1990-04-04
FI875619A7 (fi) 1988-06-23
NO875358D0 (no) 1987-12-21
AU607731B2 (en) 1991-03-14
PT86453A (en) 1988-01-01
PT86453B (pt) 1990-11-20
DK673087A (da) 1988-06-23
KR880007527A (ko) 1988-08-27
AU633666B2 (en) 1993-02-04
MY106781A (en) 1995-07-31
HU207314B (en) 1993-03-29
NO875358L (no) 1988-06-23

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment