DK633189D0 - USE OF PEPTIDISOSTERS AS RETROVIRAL PROTEASE INHIBITORS - Google Patents

USE OF PEPTIDISOSTERS AS RETROVIRAL PROTEASE INHIBITORS

Info

Publication number: DK633189D0
Authority: DK; Denmark
Prior art keywords: peptidisosters; protease inhibitors; retroviral protease; retroviral; inhibitors
Prior art date: 1988-12-15

Application number

DK633189A

Other languages

Danish (da)

Other versions

DK633189A (en

Inventor

Alexander Faessler

Ernst Hungerbuehler

Johannes Roesel

Heinrich Rueeger

Peter Schneider

Jeanette Wood

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-15

Filing date

1989-12-14

Publication date

1989-12-14

1989-12-14 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1989-12-14 Publication of DK633189D0 publication Critical patent/DK633189D0/en

1990-06-16 Publication of DK633189A publication Critical patent/DK633189A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/553—Renin inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Crystallography & Structural Chemistry (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DK633189A 1988-12-15 1989-12-14 USE OF PEPTIDISOSTERS AS RETROVIRAL PROTEASE INHIBITORS DK633189A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH464188		1988-12-15

Publications (2)

Publication Number	Publication Date
DK633189D0 true DK633189D0 (en)	1989-12-14
DK633189A DK633189A (en)	1990-06-16

Family

ID=4279922

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK633189A DK633189A (en)	1988-12-15	1989-12-14	USE OF PEPTIDISOSTERS AS RETROVIRAL PROTEASE INHIBITORS

Country Status (7)

Country	Link
EP (1)	EP0374097A3 (en)
JP (1)	JPH02212434A (en)
AU (1)	AU4678589A (en)
CA (1)	CA2005337A1 (en)
DK (1)	DK633189A (en)
IL (1)	IL92671A0 (en)
ZA (1)	ZA899559B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1340682C (en) *	1989-07-07	1999-07-27	Pierre Lavallee	Antiviral peptides having a 2-oxoalkyl amino acid side chain
DE4001236A1 (en) *	1990-01-18	1991-07-25	Bayer Ag	New oligopeptide(s) contg. 2-amino-2-methyl propionic acid residue - are antiviral agents for human or veterinary therapy including treatment of AIDS and ARC
CA2036397C (en) *	1990-02-23	2000-12-12	Paul Cates Anderson	Hiv protease inhibitors containing derived amino acid units
CA2036398C (en) *	1990-02-23	2000-06-13	Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee	Hiv protease inhibiting agents
CA2036413C (en) *	1990-02-23	2000-12-12	Paul Cates Anderson	Hiv protease inhibitors
AU7732691A (en) *	1990-06-01	1991-12-05	Ciba-Geigy Ag	Hiv protease inhibitors and processes for their preparation
WO1993023388A1 (en) *	1992-05-20	1993-11-25	G.D. Searle & Co.	Method for making intermediates useful in synthesis of retroviral protease inhibitors
DE69221309T2 (en)	1991-10-11	1997-12-11	The Du Pont Merck Pharmaceutical Co., Wilmington, Del.	CYCLIC UREAUTIES AND ANALOGA USED AS RETROVIRAL PROTEASE INHIBITORS
AU3240493A (en) *	1991-12-12	1993-07-19	Schering Corporation	Compounds and compositions for treating HIV infections
CA2091151A1 (en) *	1992-03-13	1993-09-14	Kwan Y. Hui	Retroviral protease inhibitors
TW217410B (en) *	1992-04-01	1993-12-11	Ciba Geigy
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
US5385918A (en) *	1993-02-09	1995-01-31	Miles Inc.	Aminomethylene-peptides as immunosuppressants
ATE172985T1 (en) *	1993-02-09	1998-11-15	Bayer Ag	SULFONAMIDAMINOMETHYLENE DERIVATIVES AS IMMUNOSUPPRESSANTS
EP0610745A3 (en) *	1993-02-09	1994-09-28	Miles Inc	Novel aminomethylene derivatives as immunosuppressants.
US5686469A (en) *	1993-02-09	1997-11-11	Miles Inc.	Aminomethylene derivaties as immunosuppressants
AU6491294A (en) *	1993-03-26	1994-10-24	Warner-Lambert Company	Inhibitors of endothelin converting enzyme
DE4332395A1 (en) *	1993-09-23	1995-04-13	Horst Dr Lindhofer	Inhibitors for the zymogen-like liberation cleavage of HIV-1 protease
ES2180600T3 (en) *	1994-10-19	2003-02-16	Novartis Ag	ETERES OF ISOSTEROS SUBSTRATO DE ASPARTATO PROTEASA ANTIVIRALES.
CA2191924A1 (en) *	1995-12-05	1997-06-06	Kevin Felsenstein	5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of .beta.-amyloid protein production
US5703129A (en) *	1996-09-30	1997-12-30	Bristol-Myers Squibb Company	5-amino-6-cyclohexyl-4-hydroxy-hexanamide derivatives as inhibitors of β-amyloid protein production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI843837L (en) *	1983-02-07	1984-09-28	Ferring Ab	ENZYMINHIBITORER.
US4727060A (en) *	1984-11-13	1988-02-23	Ciba-Geigy Corporation	Novel 5-amino-4-hydroxyvaleryl derivatives
BE1002213A5 (en) *	1987-04-23	1990-10-16	Sandoz Sa	NOVEL PEPTIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS.

1989
- 1989-12-06 EP EP19890810922 patent/EP0374097A3/en not_active Withdrawn
- 1989-12-13 IL IL92671A patent/IL92671A0/en unknown
- 1989-12-13 CA CA002005337A patent/CA2005337A1/en not_active Abandoned
- 1989-12-14 AU AU46785/89A patent/AU4678589A/en not_active Abandoned
- 1989-12-14 ZA ZA899559A patent/ZA899559B/en unknown
- 1989-12-14 DK DK633189A patent/DK633189A/en not_active Application Discontinuation
- 1989-12-15 JP JP1324110A patent/JPH02212434A/en active Pending

Also Published As

Publication number	Publication date
JPH02212434A (en)	1990-08-23
CA2005337A1 (en)	1990-06-15
EP0374097A2 (en)	1990-06-20
DK633189A (en)	1990-06-16
ZA899559B (en)	1990-08-29
AU4678589A (en)	1990-06-21
IL92671A0 (en)	1990-09-17
EP0374097A3 (en)	1991-06-12

Publication	Publication Date	Title
DK633189D0 (en)	1989-12-14	USE OF PEPTIDISOSTERS AS RETROVIRAL PROTEASE INHIBITORS
FI20012317L (en)	2001-11-27	Hydroxyethylaminosulfonamides useful as retroviral protease inhibitors
FI950651L (en)	1995-02-14	Sulfonylalkanoylaminohydroxyethylaminosulfonamides useful as retroviral protease inhibitors
DK674387A (en)	1988-06-23	protease inhibitors
MX9100119A (en)	1992-02-28	RETROVIRAL PROTEASE INHIBITORS
FI950841L (en)	1995-02-23	N-(alkanoylamino-2-hydroxypropyl)-sulfonamides useful as retroviral protease inhibitors
ATE241602T1 (en)	2003-06-15	SULFONAMIDE INHIBITERS OF HIV-ASPARTYL PROTEASE
DK486686A (en)	1987-04-13	USE OF BENZAMIDE DERIVATIVES
DK363887A (en)	1988-01-15	USE OF BROMCRUPTIN
FI935644A7 (en)	1994-06-17	Retroviral protease inhibitors
DK633289D0 (en)	1989-12-14	RETROVIRAL PROTEASE INHIBITORS
DK0391171T3 (en)	1993-07-12	Use of di-styryl-phenyl-triglycol ether as crystallization inhibitor
DK273089A (en)	1989-12-07	USE OF PEPTIDE DERIVATIVES
DK4687D0 (en)	1987-01-06	USE OF ESTER COMPOUNDS AS TEMPORATED MICROBICID
DK301585A (en)	1986-01-04	USE OF ACTINONIN AS IMMUNPOTENTIATOR
DK316289D0 (en)	1989-06-26	USE OF DIFLUORMETHYL-THIADIAZOLYL OXYEDIC ACID AMAMIDS AS SELECTIVE HERBICIDES
DK80990A (en)	1990-10-01	SULPHONYL DERIVATIVES OF THIEN-TRIAZOL-DIAZEPIN
FI906140A7 (en)	1991-06-17	Retroviral protease inhibitors
DK104389A (en)	1989-09-05	USE OF IMIDAZOLD DERIVATIVES
DK130390A (en)	1990-05-25	PREPARATION OF PLASMINOGEN ACTIVATOR EXPRESSED
DK369686D0 (en)	1986-08-01	PROCEDURE FOR CLEANING Tissue PLASMINOGEN ACTIVATOR
DK562289A (en)	1990-05-12	USE OF SOMATO STATINES
DK602288D0 (en)	1988-10-28	INTERMEDIATES FOR THE PREPARATION OF HALOGENED PROTEASE INHIBITORS
DK101686D0 (en)	1986-03-06	USE OF (-) - 15-DEOXYSPERGUALIN AS IMMUNOSUPPRESSIVE AGENT
DK130992D0 (en)	1992-10-27	PROCEDURE FOR THE PREPARATION OF ANGIOTENXINE-CREATING ENZYMINE INHIBITORS

Legal Events

Date	Code	Title	Description
1992-08-24	AHB	Application shelved due to non-payment
1994-12-12	AHS	Application shelved for other reasons than non-payment