DK599486A - 1,4-dihydropyridiner, deres fremstilling af anvendelse som laegemidler - Google Patents
1,4-dihydropyridiner, deres fremstilling af anvendelse som laegemidlerInfo
- Publication number
- DK599486A DK599486A DK599486A DK599486A DK599486A DK 599486 A DK599486 A DK 599486A DK 599486 A DK599486 A DK 599486A DK 599486 A DK599486 A DK 599486A DK 599486 A DK599486 A DK 599486A
- Authority
- DK
- Denmark
- Prior art keywords
- dihydropyridines
- preparation
- medicinal products
- atom
- group
- Prior art date
Links
- 229940126601 medicinal product Drugs 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853544211 DE3544211A1 (de) | 1985-12-13 | 1985-12-13 | Neue, fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK599486D0 DK599486D0 (da) | 1986-12-12 |
| DK599486A true DK599486A (da) | 1987-06-14 |
Family
ID=6288416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK599486A DK599486A (da) | 1985-12-13 | 1986-12-12 | 1,4-dihydropyridiner, deres fremstilling af anvendelse som laegemidler |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4798840A (da) |
| EP (1) | EP0225574B1 (da) |
| JP (1) | JPS62145064A (da) |
| KR (1) | KR870005993A (da) |
| CN (1) | CN86108499A (da) |
| AT (1) | ATE52773T1 (da) |
| AU (1) | AU588656B2 (da) |
| DE (2) | DE3544211A1 (da) |
| DK (1) | DK599486A (da) |
| ES (1) | ES2014975B3 (da) |
| FI (1) | FI865057A7 (da) |
| GR (1) | GR3000488T3 (da) |
| HU (1) | HU197304B (da) |
| IL (1) | IL80931A0 (da) |
| NO (1) | NO864760D0 (da) |
| PT (1) | PT83897B (da) |
| ZA (1) | ZA869376B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59410255D1 (de) * | 1993-12-10 | 2003-04-17 | Bayer Ag | Phenyl-substituierte 1,4-Dihydropyridine mit cerebraler Aktivität |
| CZ20031779A3 (cs) * | 2000-12-29 | 2004-10-13 | Bioorganicsáb@V | Způsob přípravy amlodipinuŹ jeho derivátů a jejich prekurzorů |
| KR101294702B1 (ko) * | 2006-10-18 | 2013-08-08 | (주)유케이케미팜 | Ｓ-(-)-암로디핀입체이성질체의 제조방법 |
| DE102009049137A1 (de) | 2009-10-12 | 2011-04-14 | Rhenotherm Kunststoffbeschichtungs Gmbh | Beschichtungsaufbau |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1409865A (en) * | 1973-02-13 | 1975-10-15 | Science Union & Cie | Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them |
| GB1552911A (en) * | 1975-07-02 | 1979-09-19 | Fujisawa Pharmaceutical Co | 1,4 dihydropyridine derivatives and the preparation thereof |
| GB1591089A (en) * | 1976-12-17 | 1981-06-10 | Fujisawa Pharmaceutical Co | 1,4-dihydropyridine derivatives and process for preparation thereof |
| DE2658183A1 (de) * | 1976-12-22 | 1978-07-06 | Bayer Ag | In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| JPS5395976A (en) * | 1977-02-02 | 1978-08-22 | Sankyo Co Ltd | Cyclopropyl-substituted-dihydropyridine derivatives |
| US4177278A (en) * | 1977-04-05 | 1979-12-04 | Bayer Aktiengesellschaft | 2-Alkyleneaminodihydropyridines compounds, their production and their medicinal use |
| DE2841667A1 (de) * | 1978-09-25 | 1980-04-10 | Bayer Ag | Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| US4258042A (en) * | 1980-04-11 | 1981-03-24 | Usv Pharmaceutical Corporation | Antihypertensive pyridines and compositions |
| DE3208628A1 (de) * | 1982-03-10 | 1983-09-22 | Bayer Ag, 5090 Leverkusen | Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
| EP0125803A3 (en) * | 1983-04-27 | 1987-01-21 | FISONS plc | Pharmaceutically active dihydropyridines |
-
1985
- 1985-12-13 DE DE19853544211 patent/DE3544211A1/de not_active Withdrawn
-
1986
- 1986-11-26 NO NO864760A patent/NO864760D0/no unknown
- 1986-12-01 ES ES86116657T patent/ES2014975B3/es not_active Expired - Lifetime
- 1986-12-01 DE DE8686116657T patent/DE3671221D1/de not_active Expired - Lifetime
- 1986-12-01 EP EP86116657A patent/EP0225574B1/de not_active Expired - Lifetime
- 1986-12-01 AT AT86116657T patent/ATE52773T1/de not_active IP Right Cessation
- 1986-12-04 US US06/937,764 patent/US4798840A/en not_active Expired - Fee Related
- 1986-12-10 IL IL80931A patent/IL80931A0/xx unknown
- 1986-12-10 PT PT83897A patent/PT83897B/pt unknown
- 1986-12-10 AU AU66396/86A patent/AU588656B2/en not_active Ceased
- 1986-12-11 FI FI865057A patent/FI865057A7/fi not_active Application Discontinuation
- 1986-12-12 JP JP61295054A patent/JPS62145064A/ja active Pending
- 1986-12-12 DK DK599486A patent/DK599486A/da not_active Application Discontinuation
- 1986-12-12 KR KR860010630A patent/KR870005993A/ko not_active Withdrawn
- 1986-12-12 HU HU865199A patent/HU197304B/hu not_active IP Right Cessation
- 1986-12-12 ZA ZA869376A patent/ZA869376B/xx unknown
- 1986-12-13 CN CN198686108499A patent/CN86108499A/zh active Pending
-
1990
- 1990-05-17 GR GR90400245T patent/GR3000488T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU588656B2 (en) | 1989-09-21 |
| NO864760D0 (no) | 1986-11-26 |
| CN86108499A (zh) | 1987-07-15 |
| FI865057A0 (fi) | 1986-12-11 |
| GR3000488T3 (en) | 1991-06-28 |
| EP0225574A1 (de) | 1987-06-16 |
| ATE52773T1 (de) | 1990-06-15 |
| DE3544211A1 (de) | 1987-06-19 |
| HU197304B (en) | 1989-03-28 |
| PT83897B (en) | 1988-12-14 |
| ZA869376B (en) | 1987-09-30 |
| DK599486D0 (da) | 1986-12-12 |
| IL80931A0 (en) | 1987-03-31 |
| AU6639686A (en) | 1987-06-18 |
| JPS62145064A (ja) | 1987-06-29 |
| FI865057A7 (fi) | 1987-06-14 |
| PT83897A (en) | 1987-01-01 |
| EP0225574B1 (de) | 1990-05-16 |
| DE3671221D1 (de) | 1990-06-21 |
| ES2014975B3 (es) | 1990-08-01 |
| US4798840A (en) | 1989-01-17 |
| KR870005993A (ko) | 1987-07-08 |
| HUT45013A (en) | 1988-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |