DK58291D0 - Krystalinsk stof og dets fremstilling - Google Patents
Krystalinsk stof og dets fremstillingInfo
- Publication number
- DK58291D0 DK58291D0 DK91582A DK58291A DK58291D0 DK 58291 D0 DK58291 D0 DK 58291D0 DK 91582 A DK91582 A DK 91582A DK 58291 A DK58291 A DK 58291A DK 58291 D0 DK58291 D0 DK 58291D0
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- crystaline material
- crystaline
- compositions containing
- same
- Prior art date
Links
- KOZCGZMZXXVHCF-GGMCWBHBSA-N (3R)-1-[4,4-bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid hydrate hydrochloride Chemical compound O.Cl.C1=CSC(C(=CCCN2C[C@@H](CCC2)C(O)=O)C2=C(C=CS2)C)=C1C KOZCGZMZXXVHCF-GGMCWBHBSA-N 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Mobile Radio Communication Systems (AREA)
- Transceivers (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Photoreceptors In Electrophotography (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK91582A DK58291D0 (da) | 1991-04-02 | 1991-04-02 | Krystalinsk stof og dets fremstilling |
| DK92908325T DK0579681T3 (da) | 1991-04-02 | 1992-03-23 | Krystallinsk tiagabin-hydrochlorid-monohydrat, dets fremstilling og dets anvendelse |
| CA002107223A CA2107223C (en) | 1991-04-02 | 1992-03-23 | Crystalline tiagabine hydrochloride monohydrate, its preparation and use |
| EP92908325A EP0579681B1 (en) | 1991-04-02 | 1992-03-23 | Crystalline tiagabine hydrochloride monohydrate, its preparation and use |
| PCT/DK1992/000093 WO1992017473A1 (en) | 1991-04-02 | 1992-03-23 | Crystalline tiagabine hydrochloride monohydrate, its preparation and use |
| AU16415/92A AU661483B2 (en) | 1991-04-02 | 1992-03-23 | Crystalline tiagabine hydrochloride monohydrate, its preparation and use |
| DE69229339T DE69229339T2 (de) | 1991-04-02 | 1992-03-23 | Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung |
| JP4-507965A JP3001975B2 (ja) | 1991-04-02 | 1992-03-23 | 結晶性チアガビン塩酸塩−水和物、その製造方法および用途 |
| ES92908325T ES2134801T3 (es) | 1991-04-02 | 1992-03-23 | Monohidrato de hidrocloruro de tiagabina cristalina, su preparacion y su uso. |
| AT92908325T ATE180781T1 (de) | 1991-04-02 | 1992-03-23 | Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung |
| IL10135892A IL101358A (en) | 1991-04-02 | 1992-03-24 | Crystalline tiagabine hydrochloride monohydrate its preparation and pharmaceutical composition containing it |
| US07/857,038 US5354760A (en) | 1991-04-02 | 1992-03-24 | Crystalline Tiagabine monohydrate, its preparation and use |
| ZA922297A ZA922297B (en) | 1991-04-02 | 1992-03-30 | Crystalline tiababine monohydrate,its preparation and use |
| NZ24219192A NZ242191A (en) | 1991-04-02 | 1992-04-01 | Crystalline tiagabine hydrochloride monohydrate, preparation and pharmaceutical compositions thereof |
| FI934298A FI110096B (fi) | 1991-04-02 | 1993-09-30 | Menetelmä terapeuttisesti käyttökelpoisen kiteisen Tiagabine-hydrokloridimonohydraatin valmistamiseksi |
| NO933524A NO304113B1 (no) | 1991-04-02 | 1993-10-01 | Krystallinsk tiagabinhydrokloridmonohydrat, farmas°ytisk preparat som omfatter det, og anvendelse derav for fremstilling av et medikament |
| GR990402003T GR3030919T3 (en) | 1991-04-02 | 1999-08-04 | Selective system scan for multizone radiotelephone subscriber units. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK91582A DK58291D0 (da) | 1991-04-02 | 1991-04-02 | Krystalinsk stof og dets fremstilling |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK58291D0 true DK58291D0 (da) | 1991-04-02 |
Family
ID=8095193
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91582A DK58291D0 (da) | 1991-04-02 | 1991-04-02 | Krystalinsk stof og dets fremstilling |
| DK92908325T DK0579681T3 (da) | 1991-04-02 | 1992-03-23 | Krystallinsk tiagabin-hydrochlorid-monohydrat, dets fremstilling og dets anvendelse |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92908325T DK0579681T3 (da) | 1991-04-02 | 1992-03-23 | Krystallinsk tiagabin-hydrochlorid-monohydrat, dets fremstilling og dets anvendelse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5354760A (da) |
| EP (1) | EP0579681B1 (da) |
| AT (1) | ATE180781T1 (da) |
| AU (1) | AU661483B2 (da) |
| CA (1) | CA2107223C (da) |
| DE (1) | DE69229339T2 (da) |
| DK (2) | DK58291D0 (da) |
| ES (1) | ES2134801T3 (da) |
| FI (1) | FI110096B (da) |
| GR (1) | GR3030919T3 (da) |
| IL (1) | IL101358A (da) |
| NO (1) | NO304113B1 (da) |
| NZ (1) | NZ242191A (da) |
| WO (1) | WO1992017473A1 (da) |
| ZA (1) | ZA922297B (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750140A (en) * | 1994-05-20 | 1998-05-12 | Novo Nordisk A/S | Transdermal delivery of tiagabine |
| US5866590A (en) * | 1995-05-05 | 1999-02-02 | Novo Nordisk A/S | Pharmaceutical composition containing tiagabine hydrochloride and the process for its preparation |
| DE19525598C2 (de) * | 1995-07-13 | 1997-09-25 | Max Planck Gesellschaft | Schlafmittel |
| AU736514B2 (en) * | 1995-07-13 | 2001-07-26 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Non-allosteric gabaa agonists for treating sleep disorders |
| UA52661C2 (uk) * | 1996-06-14 | 2003-01-15 | Ново Нордіск А/С | Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти |
| US5914333A (en) * | 1996-07-31 | 1999-06-22 | Novo Nordisk A/S | Treatment of psychotic disorders |
| IE970588A1 (en) | 1997-08-01 | 2000-08-23 | Elan Corp Plc | Controlled release pharmaceutical compositions containing tiagabine |
| FR2771292B1 (fr) * | 1997-11-21 | 2000-02-18 | Ethypharm Lab Prod Ethiques | Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques |
| PE20011061A1 (es) | 2000-02-01 | 2001-11-20 | Procter & Gamble | Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato |
| US6562974B2 (en) | 2000-02-01 | 2003-05-13 | The Procter & Gamble Company | Process for making geminal bisphosphonates |
| CA2477088A1 (en) | 2002-02-22 | 2003-10-02 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| WO2005122698A2 (en) * | 2003-12-24 | 2005-12-29 | Sun Pharmaceutical Industries Limited | Novel stable polymorphic forms of tiagabine hydrochloride |
| CN1314684C (zh) * | 2003-12-24 | 2007-05-09 | 中国科学院上海有机化学研究所 | 噻加宾及其消旋体和s-构型的合成方法及其无定形粉末的制法 |
| WO2005092886A1 (en) * | 2004-03-29 | 2005-10-06 | Ranbaxy Laboratories Limited | Process for the preparation of amorphous form of tiagabine |
| US20080269495A1 (en) * | 2004-08-04 | 2008-10-30 | Prosenjit Bose | Process for Preparation of Piperidine Carboxylic Acid |
| US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
| US20080051435A1 (en) * | 2006-08-18 | 2008-02-28 | Cephalon, Inc. | Crystalline and amorphous forms of tiagabine |
| US20080064727A1 (en) * | 2006-08-18 | 2008-03-13 | Cephalon, Inc. | Crystalline forms of tiagabine hydrochloride |
| CN101857591B (zh) * | 2009-04-09 | 2013-06-05 | 北京京卫燕康药物研究所有限公司 | 盐酸噻加宾晶型及其制备方法 |
| CN103554093B (zh) * | 2013-11-12 | 2015-10-21 | 四川科瑞德凯华制药有限公司 | 噻加宾乙酯盐酸盐及其制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK288385D0 (da) * | 1985-06-26 | 1985-06-26 | Novo Industri As | Aminosyrederivater |
| ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
| US4910312A (en) * | 1985-11-08 | 1990-03-20 | Warner-Lambert Company | Various N-substituted 3-piperidine carboxylic acids or N-substituted 3-pyridinecarboxylic acids and derivatives thereof |
-
1991
- 1991-04-02 DK DK91582A patent/DK58291D0/da not_active Application Discontinuation
-
1992
- 1992-03-23 DK DK92908325T patent/DK0579681T3/da active
- 1992-03-23 AT AT92908325T patent/ATE180781T1/de active
- 1992-03-23 CA CA002107223A patent/CA2107223C/en not_active Expired - Lifetime
- 1992-03-23 AU AU16415/92A patent/AU661483B2/en not_active Expired
- 1992-03-23 WO PCT/DK1992/000093 patent/WO1992017473A1/en not_active Ceased
- 1992-03-23 ES ES92908325T patent/ES2134801T3/es not_active Expired - Lifetime
- 1992-03-23 EP EP92908325A patent/EP0579681B1/en not_active Expired - Lifetime
- 1992-03-23 DE DE69229339T patent/DE69229339T2/de not_active Expired - Lifetime
- 1992-03-24 IL IL10135892A patent/IL101358A/en not_active IP Right Cessation
- 1992-03-24 US US07/857,038 patent/US5354760A/en not_active Expired - Lifetime
- 1992-03-30 ZA ZA922297A patent/ZA922297B/xx unknown
- 1992-04-01 NZ NZ24219192A patent/NZ242191A/en not_active IP Right Cessation
-
1993
- 1993-09-30 FI FI934298A patent/FI110096B/fi not_active IP Right Cessation
- 1993-10-01 NO NO933524A patent/NO304113B1/no not_active IP Right Cessation
-
1999
- 1999-08-04 GR GR990402003T patent/GR3030919T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2134801T3 (es) | 1999-10-16 |
| WO1992017473A1 (en) | 1992-10-15 |
| FI934298A0 (fi) | 1993-09-30 |
| DE69229339T2 (de) | 1999-12-30 |
| CA2107223C (en) | 2005-02-15 |
| NZ242191A (en) | 1994-07-26 |
| FI110096B (fi) | 2002-11-29 |
| CA2107223A1 (en) | 1992-10-03 |
| ATE180781T1 (de) | 1999-06-15 |
| EP0579681A1 (en) | 1994-01-26 |
| US5354760A (en) | 1994-10-11 |
| IL101358A0 (en) | 1992-11-15 |
| EP0579681B1 (en) | 1999-06-02 |
| DK0579681T3 (da) | 1999-11-15 |
| NO933524D0 (no) | 1993-10-01 |
| DE69229339D1 (de) | 1999-07-08 |
| JPH06506209A (ja) | 1994-07-14 |
| GR3030919T3 (en) | 1999-11-30 |
| AU661483B2 (en) | 1995-07-27 |
| FI934298L (fi) | 1993-09-30 |
| AU1641592A (en) | 1992-11-02 |
| ZA922297B (en) | 1992-12-30 |
| IL101358A (en) | 1996-08-04 |
| NO304113B1 (no) | 1998-10-26 |
| NO933524L (no) | 1993-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |