DK580077A - Fremgangsmaade til stabilisering koncentrering og rensning af insulin - Google Patents
Fremgangsmaade til stabilisering koncentrering og rensning af insulinInfo
- Publication number
- DK580077A DK580077A DK580077A DK580077A DK580077A DK 580077 A DK580077 A DK 580077A DK 580077 A DK580077 A DK 580077A DK 580077 A DK580077 A DK 580077A DK 580077 A DK580077 A DK 580077A
- Authority
- DK
- Denmark
- Prior art keywords
- cleaning
- insulin concentration
- stabilization procedure
- stabilization
- procedure
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 238000004140 cleaning Methods 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C07K14/625—Extraction from natural sources
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75411276A | 1976-12-27 | 1976-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK580077A true DK580077A (da) | 1978-06-28 |
Family
ID=25033538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK580077A DK580077A (da) | 1976-12-27 | 1977-12-23 | Fremgangsmaade til stabilisering koncentrering og rensning af insulin |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS53115809A (da) |
| AR (1) | AR221693A1 (da) |
| AU (1) | AU3172477A (da) |
| DE (1) | DE2757377A1 (da) |
| DK (1) | DK580077A (da) |
| FR (1) | FR2375193A1 (da) |
| GB (1) | GB1587769A (da) |
| NL (1) | NL7713966A (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5397579A (en) * | 1978-12-26 | 1980-07-03 | Eli Lilly And Company | Purifying insulin |
| DK374579A (da) * | 1979-09-07 | 1981-03-08 | Nordisk Insulinlab | Fremgangsmaade til fremstilling af et injucerbart insulinpraeparat |
| DE3726655A1 (de) * | 1987-08-11 | 1989-02-23 | Hoechst Ag | Verfahren zur isolierung basischer proteine aus proteingemischen, welche solche basischen proteine enthalten |
| RU2603752C2 (ru) | 2011-02-01 | 2016-11-27 | Ново Нордиск А/С | Очистка инсулина |
| WO2014099577A1 (en) * | 2012-12-17 | 2014-06-26 | Merck Sharp & Dohme Corp. | Process for purifying insulin and analogues thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1186144A (fr) * | 1955-02-09 | 1959-08-14 | Procédé de préparation de l'insuline à partir du pancréas | |
| US3069323A (en) * | 1959-09-14 | 1962-12-18 | Armour Pharma | Insulin recovery process |
| FR1267495A (fr) * | 1960-09-13 | 1961-07-21 | Armour & Co | Procédé de récupération d'insuline cristallisée |
| GB1054523A (da) * | 1965-11-17 | 1900-01-01 | ||
| GB1285023A (en) * | 1968-08-09 | 1972-08-09 | Novo Terapeutisk Labor As | Improvements in or relating to injectable insulin preparations |
| AT304760B (de) * | 1969-08-08 | 1973-01-25 | Novo Terapeutisk Labor As | Verfahren zur Reinigung von Insulin |
-
1977
- 1977-12-16 NL NL7713966A patent/NL7713966A/xx not_active Application Discontinuation
- 1977-12-19 AU AU31724/77A patent/AU3172477A/en active Pending
- 1977-12-22 DE DE19772757377 patent/DE2757377A1/de not_active Withdrawn
- 1977-12-22 GB GB5352777A patent/GB1587769A/en not_active Expired
- 1977-12-23 DK DK580077A patent/DK580077A/da not_active Application Discontinuation
- 1977-12-26 AR AR27051077A patent/AR221693A1/es active
- 1977-12-26 FR FR7739176A patent/FR2375193A1/fr not_active Withdrawn
- 1977-12-27 JP JP15857577A patent/JPS53115809A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS53115809A (en) | 1978-10-09 |
| DE2757377A1 (de) | 1978-06-29 |
| FR2375193A1 (fr) | 1978-07-21 |
| AR221693A1 (es) | 1981-03-13 |
| AU3172477A (en) | 1979-06-28 |
| GB1587769A (en) | 1981-04-08 |
| NL7713966A (nl) | 1978-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |