DK584489D0 - PROCEDURE FOR THE PREPARATION OF TRIPEPTIDES - Google Patents
PROCEDURE FOR THE PREPARATION OF TRIPEPTIDESInfo
- Publication number
- DK584489D0 DK584489D0 DK584489A DK584489A DK584489D0 DK 584489 D0 DK584489 D0 DK 584489D0 DK 584489 A DK584489 A DK 584489A DK 584489 A DK584489 A DK 584489A DK 584489 D0 DK584489 D0 DK 584489D0
- Authority
- DK
- Denmark
- Prior art keywords
- general formula
- compound
- tripeptides
- procedure
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910014033 C-OH Inorganic materials 0.000 abstract 1
- 229910014570 C—OH Inorganic materials 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
- C07K1/082—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents containing phosphorus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Process for preparing tripeptides of the general formula I U-A-B-C-OH I in which U is hydrogen or a urethane protective group and A, B and C are amino acids, by reacting a compound of the general formula II U'-B-OH II in which U' is a urethane protective group which can be eliminated by hydrogenolysis, with a compound of the general formula III H-C-OR III in which R is alkyl, by the PPA method, eliminating U', reacting the compound obtained in this way with a compound of the general formula IV H-B-C-OR IV by the PPA method and subsequently eliminating R enzymatically.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3839379A DE3839379A1 (en) | 1988-11-22 | 1988-11-22 | METHOD FOR PRODUCING TRIPEPTIDES |
| DE3839379 | 1988-11-22 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK584489D0 true DK584489D0 (en) | 1989-11-21 |
| DK584489A DK584489A (en) | 1990-05-23 |
| DK173690B1 DK173690B1 (en) | 2001-06-25 |
Family
ID=6367619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198905844A DK173690B1 (en) | 1988-11-22 | 1989-11-21 | Process for the preparation of tripeptides |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0370399B1 (en) |
| JP (1) | JP2843618B2 (en) |
| AT (1) | ATE124053T1 (en) |
| AU (1) | AU626608B2 (en) |
| CA (1) | CA1335493C (en) |
| DE (2) | DE3839379A1 (en) |
| DK (1) | DK173690B1 (en) |
| ES (1) | ES2075028T3 (en) |
| IE (1) | IE67293B1 (en) |
| IL (1) | IL92368A0 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004029812A1 (en) * | 2004-06-19 | 2006-05-24 | Clariant Gmbh | Process for the preparation of nitriles from aldehyde oximes by reaction with alkylphosphonic anhydrides |
| DE102004029811A1 (en) * | 2004-06-19 | 2006-01-12 | Clariant Gmbh | Process for the preparation of alkenes by elimination of water from alcohols with alkylphosphonic anhydrides |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7801373L (en) * | 1978-02-07 | 1979-08-08 | Kabi Ab | EASY SPLABLE SUBSTRATE FOR QUANTIFIATION OF PROTEASES |
| US4293648A (en) * | 1979-12-12 | 1981-10-06 | G. D. Searle & Co. | Process for esterification of α-L-aspartyl-L-phenylalanine |
| DE3411224A1 (en) * | 1984-03-27 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | METHOD FOR THE RACEMATAR PRODUCTION OF INTERMEDIATE PEPTIDE PRODUCTS OF THE GONADORELIN AND GONADORELINANALOGA SYNTHESIS AND NEW INTERMEDIATE PRODUCTS IN THIS METHOD |
| DE3438189A1 (en) * | 1984-10-18 | 1986-04-24 | Hoechst Ag, 6230 Frankfurt | METHOD FOR PRODUCING AROMATICALLY SUBSTITUTED L-AMINO ACIDS |
| US4888385A (en) * | 1987-04-30 | 1989-12-19 | Millipore Corporation | BOP reagent for solid phase peptide synthesis |
| US4946942A (en) * | 1988-03-11 | 1990-08-07 | Bioresearch, Inc. | Urethane-protected amino acid-N-carboxyanhydrides |
-
1988
- 1988-11-22 DE DE3839379A patent/DE3839379A1/en not_active Withdrawn
-
1989
- 1989-09-29 CA CA000614545A patent/CA1335493C/en not_active Expired - Lifetime
- 1989-11-17 EP EP89121277A patent/EP0370399B1/en not_active Expired - Lifetime
- 1989-11-17 AT AT89121277T patent/ATE124053T1/en not_active IP Right Cessation
- 1989-11-17 DE DE58909308T patent/DE58909308D1/en not_active Expired - Lifetime
- 1989-11-17 ES ES89121277T patent/ES2075028T3/en not_active Expired - Lifetime
- 1989-11-20 IL IL92368A patent/IL92368A0/en not_active IP Right Cessation
- 1989-11-21 DK DK198905844A patent/DK173690B1/en not_active IP Right Cessation
- 1989-11-21 JP JP1300960A patent/JP2843618B2/en not_active Expired - Lifetime
- 1989-11-21 IE IE371789A patent/IE67293B1/en not_active IP Right Cessation
- 1989-11-21 AU AU45328/89A patent/AU626608B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0370399A3 (en) | 1991-09-18 |
| DE3839379A1 (en) | 1990-05-23 |
| AU626608B2 (en) | 1992-08-06 |
| JPH02219587A (en) | 1990-09-03 |
| CA1335493C (en) | 1995-05-09 |
| DE58909308D1 (en) | 1995-07-27 |
| ES2075028T3 (en) | 1995-10-01 |
| ATE124053T1 (en) | 1995-07-15 |
| DK173690B1 (en) | 2001-06-25 |
| IE67293B1 (en) | 1996-03-20 |
| IE893717L (en) | 1990-05-22 |
| DK584489A (en) | 1990-05-23 |
| IL92368A0 (en) | 1990-07-26 |
| JP2843618B2 (en) | 1999-01-06 |
| EP0370399B1 (en) | 1995-06-21 |
| AU4532889A (en) | 1990-05-31 |
| EP0370399A2 (en) | 1990-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |