DK574685A - Aktive forbindelser - Google Patents
Aktive forbindelser Download PDFInfo
- Publication number
- DK574685A DK574685A DK574685A DK574685A DK574685A DK 574685 A DK574685 A DK 574685A DK 574685 A DK574685 A DK 574685A DK 574685 A DK574685 A DK 574685A DK 574685 A DK574685 A DK 574685A
- Authority
- DK
- Denmark
- Prior art keywords
- active relationships
- relationships
- active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848431478A GB8431478D0 (en) | 1984-12-13 | 1984-12-13 | Compounds |
| GB858520619A GB8520619D0 (en) | 1985-08-16 | 1985-08-16 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK574685D0 DK574685D0 (da) | 1985-12-11 |
| DK574685A true DK574685A (da) | 1986-06-14 |
Family
ID=26288569
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK574685A DK574685A (da) | 1984-12-13 | 1985-12-11 | Aktive forbindelser |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0190496A3 (da) |
| AU (1) | AU5111485A (da) |
| DK (1) | DK574685A (da) |
| GR (1) | GR853000B (da) |
| PT (1) | PT81662B (da) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0223403B1 (en) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
| DK231088D0 (da) * | 1988-04-28 | 1988-04-28 | Ferrosan As | Piperidinforbindelser, deres fremstilling og anvendelse |
| GB8714707D0 (en) * | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
| DK588289D0 (da) * | 1989-11-22 | 1989-11-22 | Ferrosan As | Ny heterocyklisk kemi |
| US5169855A (en) * | 1990-03-28 | 1992-12-08 | Du Pont Merck Pharmaceutical Company | Piperidine ether derivatives as psychotropic drugs or plant fungicides |
| IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
| ES2102295B1 (es) * | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
| US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
| GB9526645D0 (en) * | 1995-12-28 | 1996-02-28 | Chiroscience Ltd | Stereoselective synthesis |
| ES2121684B1 (es) * | 1996-03-15 | 1999-08-16 | Vita Invest Sa | Procedimiento para la obtencion de (+)-cis / (+)-trans-4-(4-fluorofenil)-1-metilpiperidina-3-carboxilato de etilo. |
| ES2121685B1 (es) * | 1996-04-10 | 1999-09-16 | Vita Invest Sa | Procedimiento para la obtencion de (+)-trans-4(4-fluoro-fenil)-3-hidroximetil-1-metilpiperidina. |
| JP3446468B2 (ja) | 1996-04-15 | 2003-09-16 | 旭硝子株式会社 | ピペリジンカルビノール類の製造方法 |
| JP3882224B2 (ja) | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
| EP1384711A1 (en) * | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Optical resolution of a piperidine derivative |
| HU221921B1 (hu) | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
| GB9623359D0 (en) * | 1996-11-09 | 1997-01-08 | Smithkline Beecham Plc | Novel process |
| PL337513A1 (en) | 1997-05-29 | 2000-08-28 | Smithkline Beecham Corp | Novel method of obtaining pharmaceutically active compounds and their associated intermediate products |
| AU2002301956B2 (en) * | 1997-06-10 | 2006-02-09 | Synthon B.V. | 4-phenylpiperidine compounds |
| HUP0003141A3 (en) * | 1997-06-10 | 2001-04-28 | Synthon Bv | 4-phenylpiperidine derivatives, process for producing them and pharmaceutical compositions containing them |
| ES2149687B1 (es) * | 1998-04-08 | 2001-05-16 | Medichem Sa | Procedimiento de obtencion de (+-)-trans-4-(4-fluorofenil)-3-hidroximetilpiperidinas e intermedios de sintesis para las mismas. |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| WO2000037443A1 (en) * | 1998-12-22 | 2000-06-29 | Pentech Pharmaceuticals, Inc. | Process for preparing arylpiperidine carbinol intermediates and derivatives |
| GB9914583D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel process |
| GB9916187D0 (en) * | 1999-07-09 | 1999-09-08 | Smithkline Beecham Plc | Novel process |
| IT1313702B1 (it) * | 1999-08-02 | 2002-09-09 | Chemi Spa | Processo per la preparazione di derivati 3-sostituiti di 4-fenil-piperidine. |
| CZ20023694A3 (cs) * | 2000-05-12 | 2003-05-14 | Synthon B. V. | Tosylátové soli 4-(p-fluorfenyl)-piperidin-3-methanolů |
| DE60007782T2 (de) * | 2000-05-12 | 2004-12-09 | Synthon B.V. | Piperidinverbindungen und verfahren zu deren herstellung |
| JP2004509103A (ja) * | 2000-09-11 | 2004-03-25 | セプレイコー インコーポレイテッド | モノアミン受容体及び輸送体のリガンドならびにその使用方法 |
| NL1017421C2 (nl) | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| US20030032809A1 (en) * | 2001-04-25 | 2003-02-13 | Subhash P. Upadhyaya | Optimized procedures for the manufacture of paroxetine salts |
| US6956121B2 (en) * | 2002-03-01 | 2005-10-18 | Teva Pharmaceutical Industries Ltd. | Preparation of paroxetine involving novel intermediates |
| CA2502704A1 (en) * | 2002-11-01 | 2004-05-13 | Neurosearch A/S | Novel piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| WO2004043921A1 (en) * | 2002-11-11 | 2004-05-27 | Natco Pharma Limited | Novel process for the preparation of 4-aryl-3-hydroxymethyl-1-methylpiperidines. |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| MX2008012566A (es) * | 2006-04-03 | 2008-10-10 | Hoffmann La Roche | Proceso para preparar acidos beta-aril o heteroaril-carboxilicos ciclicos enantiomericamente enriquecidos. |
| JP5598798B2 (ja) | 2008-11-14 | 2014-10-01 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | ４−［２−（２−フルオロフェノキシメチル）フェニル］ピペリジン化合物を調製するためのプロセス |
| US8778949B2 (en) | 2010-01-11 | 2014-07-15 | Theravance Biopharma R&D Ip, Llc | 1-(2-phenoxymethylphenyl)piperazine compounds |
| ES2543064T3 (es) | 2010-03-22 | 2015-08-14 | Theravance Biopharma R&D Ip, Llc | Compuestos de 1-(2-fenoximetilheteroaril)piperidina y piperazina |
| CN111533682B (zh) * | 2020-05-29 | 2022-03-01 | 清华大学 | 帕罗西汀及其类似物的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
-
1985
- 1985-12-09 EP EP85308936A patent/EP0190496A3/en not_active Withdrawn
- 1985-12-11 DK DK574685A patent/DK574685A/da not_active Application Discontinuation
- 1985-12-11 AU AU51114/85A patent/AU5111485A/en not_active Abandoned
- 1985-12-12 PT PT8166285A patent/PT81662B/pt unknown
- 1985-12-12 GR GR853000A patent/GR853000B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR853000B (da) | 1986-04-16 |
| DK574685D0 (da) | 1985-12-11 |
| EP0190496A3 (en) | 1987-05-27 |
| EP0190496A2 (en) | 1986-08-13 |
| PT81662A (en) | 1986-01-01 |
| PT81662B (en) | 1987-10-09 |
| AU5111485A (en) | 1986-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |