DK562783D0 - Pyrrolidinderivater og deres fremstilling samt laegemidler indeholdende saadanne derivater - Google Patents
Pyrrolidinderivater og deres fremstilling samt laegemidler indeholdende saadanne derivaterInfo
- Publication number
- DK562783D0 DK562783D0 DK5627/83A DK562783A DK562783D0 DK 562783 D0 DK562783 D0 DK 562783D0 DK 5627/83 A DK5627/83 A DK 5627/83A DK 562783 A DK562783 A DK 562783A DK 562783 D0 DK562783 D0 DK 562783D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- radical
- alkoxy
- atom
- alkylthio
- Prior art date
Links
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1
- 239000004615 ingredient Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- -1 nitro, amino Chemical group 0.000 abstract 3
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003235 pyrrolidines Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8220492A FR2537133A1 (fr) | 1982-12-07 | 1982-12-07 | Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK562783D0 true DK562783D0 (da) | 1983-12-06 |
| DK562783A DK562783A (da) | 1984-06-08 |
Family
ID=9279863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK562783A DK562783A (da) | 1982-12-07 | 1983-12-06 | Pyrrolidinderivater og deres fremstilling samt laegemidler indeholdende saadanne derivater |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4547504A (da) |
| EP (1) | EP0110795B1 (da) |
| JP (1) | JPS59110670A (da) |
| AT (1) | ATE18548T1 (da) |
| AU (1) | AU560075B2 (da) |
| BG (1) | BG40808A3 (da) |
| CA (1) | CA1208645A (da) |
| CS (1) | CS240982B2 (da) |
| DD (1) | DD213216A5 (da) |
| DE (1) | DE3362566D1 (da) |
| DK (1) | DK562783A (da) |
| ES (1) | ES527897A0 (da) |
| FI (1) | FI76320C (da) |
| FR (1) | FR2537133A1 (da) |
| GR (1) | GR72855B (da) |
| HU (1) | HU191903B (da) |
| IE (1) | IE56453B1 (da) |
| IL (1) | IL70396A (da) |
| MA (1) | MA19966A1 (da) |
| NO (1) | NO158218C (da) |
| NZ (1) | NZ206498A (da) |
| PL (1) | PL141385B1 (da) |
| PT (1) | PT77774B (da) |
| SU (1) | SU1240359A3 (da) |
| ZA (1) | ZA839070B (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0241053B1 (en) * | 1986-02-27 | 1992-11-11 | Duphar International Research B.V | Aryl-substituted (n-piperidinyl)-methyl- and (n-piperazinyl) methylazoles having antipsychotic properties |
| DK0402644T3 (da) * | 1989-05-19 | 1996-01-02 | Hoechst Roussel Pharma | N-(Aryloxyalkyl)-heteroarylpiperidiner og -heteroarylpiperaziner, fremgangsmåde til deres fremstilli ng samt deres anvendelse som medikamenter |
| US5066663A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors |
| DE19540027A1 (de) * | 1995-10-27 | 1997-04-30 | Gruenenthal Gmbh | Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe |
| US6897213B1 (en) | 1995-11-21 | 2005-05-24 | Warner-Lambert Company | Heterocycles as cholecystokinin (CCK) ligands |
| US5969138A (en) * | 1996-11-01 | 1999-10-19 | Mitsui Chemicals, Inc. | Pyrrolidinone derivatives |
| ES2237850T3 (es) * | 1997-10-14 | 2005-08-01 | Mitsubishi Pharma Corporation | Compuestos de piperazina y su uso medicinal. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
-
1982
- 1982-12-07 FR FR8220492A patent/FR2537133A1/fr active Granted
-
1983
- 1983-12-02 CS CS839041A patent/CS240982B2/cs unknown
- 1983-12-05 GR GR73154A patent/GR72855B/el unknown
- 1983-12-05 PL PL1983244921A patent/PL141385B1/pl unknown
- 1983-12-05 DD DD83257518A patent/DD213216A5/de unknown
- 1983-12-05 FI FI834453A patent/FI76320C/fi not_active IP Right Cessation
- 1983-12-06 US US06/558,775 patent/US4547504A/en not_active Expired - Fee Related
- 1983-12-06 HU HU834166A patent/HU191903B/hu unknown
- 1983-12-06 MA MA20187A patent/MA19966A1/fr unknown
- 1983-12-06 DK DK562783A patent/DK562783A/da not_active Application Discontinuation
- 1983-12-06 AT AT83402354T patent/ATE18548T1/de not_active IP Right Cessation
- 1983-12-06 NZ NZ206498A patent/NZ206498A/en unknown
- 1983-12-06 SU SU833673511A patent/SU1240359A3/ru active
- 1983-12-06 AU AU22108/83A patent/AU560075B2/en not_active Ceased
- 1983-12-06 PT PT77774A patent/PT77774B/pt unknown
- 1983-12-06 DE DE8383402354T patent/DE3362566D1/de not_active Expired
- 1983-12-06 ZA ZA839070A patent/ZA839070B/xx unknown
- 1983-12-06 IE IE2867/83A patent/IE56453B1/xx unknown
- 1983-12-06 EP EP83402354A patent/EP0110795B1/fr not_active Expired
- 1983-12-06 CA CA000442681A patent/CA1208645A/fr not_active Expired
- 1983-12-06 NO NO834481A patent/NO158218C/no unknown
- 1983-12-06 IL IL70396A patent/IL70396A/xx not_active IP Right Cessation
- 1983-12-06 JP JP58229251A patent/JPS59110670A/ja active Pending
- 1983-12-07 ES ES527897A patent/ES527897A0/es active Granted
- 1983-12-07 BG BG063371A patent/BG40808A3/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |